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1hoe
From Proteopedia
(Difference between revisions)
(New page: 200px<br /><applet load="1hoe" size="450" color="white" frame="true" align="right" spinBox="true" caption="1hoe, resolution 2.0Å" /> '''CRYSTAL STRUCTURE DET...) |
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| - | [[Image:1hoe.gif|left|200px]]<br /><applet load="1hoe" size="450" color="white" frame="true" align="right" spinBox="true" | ||
| - | caption="1hoe, resolution 2.0Å" /> | ||
| - | '''CRYSTAL STRUCTURE DETERMINATION, REFINEMENT AND THE MOLECULAR MODEL OF THE ALPHA-AMYLASE INHIBITOR HOE-467A'''<br /> | ||
| - | == | + | ==CRYSTAL STRUCTURE DETERMINATION, REFINEMENT AND THE MOLECULAR MODEL OF THE ALPHA-AMYLASE INHIBITOR HOE-467A== |
| - | + | <StructureSection load='1hoe' size='340' side='right'caption='[[1hoe]], [[Resolution|resolution]] 2.00Å' scene=''> | |
| - | + | == Structural highlights == | |
| - | == | + | <table><tr><td colspan='2'>[[1hoe]] is a 1 chain structure with sequence from [https://en.wikipedia.org/wiki/Streptomyces_tendae Streptomyces tendae]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=1HOE OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=1HOE FirstGlance]. <br> |
| - | + | </td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models|Method:]]</b></td><td class="sblockDat" id="methodDat">X-ray diffraction, [[Resolution|Resolution]] 2Å</td></tr> | |
| - | + | <tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=1hoe FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=1hoe OCA], [https://pdbe.org/1hoe PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=1hoe RCSB], [https://www.ebi.ac.uk/pdbsum/1hoe PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=1hoe ProSAT]</span></td></tr> | |
| - | == | + | </table> |
| - | + | == Function == | |
| - | [[Category: | + | [https://www.uniprot.org/uniprot/IAA_STRTE IAA_STRTE] Inhibits mammalian alpha-amylases specifically but has no action on plant and microbial alpha-amylases. Forms a tight stoichiometric 1:1 complex with alpha-amylase. |
| + | == Evolutionary Conservation == | ||
| + | [[Image:Consurf_key_small.gif|200px|right]] | ||
| + | Check<jmol> | ||
| + | <jmolCheckbox> | ||
| + | <scriptWhenChecked>; select protein; define ~consurf_to_do selected; consurf_initial_scene = true; script "/wiki/ConSurf/ho/1hoe_consurf.spt"</scriptWhenChecked> | ||
| + | <scriptWhenUnchecked>script /wiki/extensions/Proteopedia/spt/initialview01.spt</scriptWhenUnchecked> | ||
| + | <text>to colour the structure by Evolutionary Conservation</text> | ||
| + | </jmolCheckbox> | ||
| + | </jmol>, as determined by [http://consurfdb.tau.ac.il/ ConSurfDB]. You may read the [[Conservation%2C_Evolutionary|explanation]] of the method and the full data available from [http://bental.tau.ac.il/new_ConSurfDB/main_output.php?pdb_ID=1hoe ConSurf]. | ||
| + | <div style="clear:both"></div> | ||
| + | __TOC__ | ||
| + | </StructureSection> | ||
| + | [[Category: Large Structures]] | ||
[[Category: Streptomyces tendae]] | [[Category: Streptomyces tendae]] | ||
| - | [[Category: Huber | + | [[Category: Huber R]] |
| - | [[Category: Pflugrath | + | [[Category: Pflugrath JW]] |
| - | [[Category: Wiegand | + | [[Category: Wiegand G]] |
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Current revision
CRYSTAL STRUCTURE DETERMINATION, REFINEMENT AND THE MOLECULAR MODEL OF THE ALPHA-AMYLASE INHIBITOR HOE-467A
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