This old version of Proteopedia is provided for student assignments while the new version is undergoing repairs. Content and edits done in this old version of Proteopedia after March 1, 2026 will eventually be lost when it is retired in about June of 2026.


Apply for new accounts at the new Proteopedia. Your logins will work in both the old and new versions.


1kk0

From Proteopedia

(Difference between revisions)
Jump to: navigation, search
Current revision (08:00, 3 April 2024) (edit) (undo)
 
(10 intermediate revisions not shown.)
Line 1: Line 1:
-
{{Seed}}
 
-
[[Image:1kk0.png|left|200px]]
 
-
<!--
+
==Structure of the large gamma subunit of initiation factor eIF2 from Pyrococcus abyssi==
-
The line below this paragraph, containing "STRUCTURE_1kk0", creates the "Structure Box" on the page.
+
<StructureSection load='1kk0' size='340' side='right'caption='[[1kk0]], [[Resolution|resolution]] 1.95&Aring;' scene=''>
-
You may change the PDB parameter (which sets the PDB file loaded into the applet)
+
== Structural highlights ==
-
or the SCENE parameter (which sets the initial scene displayed when the page is loaded),
+
<table><tr><td colspan='2'>[[1kk0]] is a 1 chain structure with sequence from [https://en.wikipedia.org/wiki/Pyrococcus_abyssi Pyrococcus abyssi]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=1KK0 OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=1KK0 FirstGlance]. <br>
-
or leave the SCENE parameter empty for the default display.
+
</td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models|Method:]]</b></td><td class="sblockDat" id="methodDat">X-ray diffraction, [[Resolution|Resolution]] 1.95&#8491;</td></tr>
-
-->
+
<tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=MSE:SELENOMETHIONINE'>MSE</scene>, <scene name='pdbligand=ZN:ZINC+ION'>ZN</scene></td></tr>
-
{{STRUCTURE_1kk0| PDB=1kk0 | SCENE= }}
+
<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=1kk0 FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=1kk0 OCA], [https://pdbe.org/1kk0 PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=1kk0 RCSB], [https://www.ebi.ac.uk/pdbsum/1kk0 PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=1kk0 ProSAT]</span></td></tr>
-
 
+
</table>
-
===Structure of the large gamma subunit of initiation factor eIF2 from Pyrococcus abyssi===
+
== Function ==
-
 
+
[https://www.uniprot.org/uniprot/IF2G_PYRAB IF2G_PYRAB] eIF-2 functions in the early steps of protein synthesis by forming a ternary complex with GTP and initiator tRNA (By similarity).
-
 
+
== Evolutionary Conservation ==
-
<!--
+
[[Image:Consurf_key_small.gif|200px|right]]
-
The line below this paragraph, {{ABSTRACT_PUBMED_11927566}}, adds the Publication Abstract to the page
+
Check<jmol>
-
(as it appears on PubMed at http://www.pubmed.gov), where 11927566 is the PubMed ID number.
+
<jmolCheckbox>
-
-->
+
<scriptWhenChecked>; select protein; define ~consurf_to_do selected; consurf_initial_scene = true; script "/wiki/ConSurf/kk/1kk0_consurf.spt"</scriptWhenChecked>
-
{{ABSTRACT_PUBMED_11927566}}
+
<scriptWhenUnchecked>script /wiki/extensions/Proteopedia/spt/initialview01.spt</scriptWhenUnchecked>
-
 
+
<text>to colour the structure by Evolutionary Conservation</text>
-
==About this Structure==
+
</jmolCheckbox>
-
1KK0 is a [[Single protein]] structure of sequence from [http://en.wikipedia.org/wiki/Pyrococcus_abyssi Pyrococcus abyssi]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=1KK0 OCA].
+
</jmol>, as determined by [http://consurfdb.tau.ac.il/ ConSurfDB]. You may read the [[Conservation%2C_Evolutionary|explanation]] of the method and the full data available from [http://bental.tau.ac.il/new_ConSurfDB/main_output.php?pdb_ID=1kk0 ConSurf].
-
 
+
<div style="clear:both"></div>
-
==Reference==
+
__TOC__
-
The large subunit of initiation factor aIF2 is a close structural homologue of elongation factors., Schmitt E, Blanquet S, Mechulam Y, EMBO J. 2002 Apr 2;21(7):1821-32. PMID:[http://www.ncbi.nlm.nih.gov/pubmed/11927566 11927566]
+
</StructureSection>
 +
[[Category: Large Structures]]
[[Category: Pyrococcus abyssi]]
[[Category: Pyrococcus abyssi]]
-
[[Category: Single protein]]
+
[[Category: Blanquet S]]
-
[[Category: Blanquet, S.]]
+
[[Category: Mechulam Y]]
-
[[Category: Mechulam, Y.]]
+
[[Category: Schmitt E]]
-
[[Category: Schmitt, E.]]
+
-
[[Category: Initiation of translation]]
+
-
 
+
-
''Page seeded by [http://oca.weizmann.ac.il/oca OCA ] on Wed Jul 2 10:27:19 2008''
+

Current revision

Structure of the large gamma subunit of initiation factor eIF2 from Pyrococcus abyssi

PDB ID 1kk0

Drag the structure with the mouse to rotate

Proteopedia Page Contributors and Editors (what is this?)

OCA

Personal tools