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1kor

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{{Seed}}
 
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[[Image:1kor.png|left|200px]]
 
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<!--
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==Crystal Structure of Thermus thermophilus HB8 Argininosuccinate Synthetase in complex with inhibitors==
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The line below this paragraph, containing "STRUCTURE_1kor", creates the "Structure Box" on the page.
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<StructureSection load='1kor' size='340' side='right'caption='[[1kor]], [[Resolution|resolution]] 1.95&Aring;' scene=''>
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You may change the PDB parameter (which sets the PDB file loaded into the applet)
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== Structural highlights ==
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or the SCENE parameter (which sets the initial scene displayed when the page is loaded),
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<table><tr><td colspan='2'>[[1kor]] is a 4 chain structure with sequence from [https://en.wikipedia.org/wiki/Thermus_thermophilus Thermus thermophilus]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=1KOR OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=1KOR FirstGlance]. <br>
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or leave the SCENE parameter empty for the default display.
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</td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models|Method:]]</b></td><td class="sblockDat" id="methodDat">X-ray diffraction, [[Resolution|Resolution]] 1.95&#8491;</td></tr>
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<tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=ANP:PHOSPHOAMINOPHOSPHONIC+ACID-ADENYLATE+ESTER'>ANP</scene>, <scene name='pdbligand=ARG:ARGININE'>ARG</scene>, <scene name='pdbligand=SIN:SUCCINIC+ACID'>SIN</scene></td></tr>
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{{STRUCTURE_1kor| PDB=1kor | SCENE= }}
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<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=1kor FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=1kor OCA], [https://pdbe.org/1kor PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=1kor RCSB], [https://www.ebi.ac.uk/pdbsum/1kor PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=1kor ProSAT], [https://www.topsan.org/Proteins/RSGI/1kor TOPSAN]</span></td></tr>
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</table>
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===Crystal Structure of Thermus thermophilus HB8 Argininosuccinate Synthetase in complex with inhibitors===
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== Function ==
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[https://www.uniprot.org/uniprot/ASSY_THET8 ASSY_THET8]
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== Evolutionary Conservation ==
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<!--
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[[Image:Consurf_key_small.gif|200px|right]]
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The line below this paragraph, {{ABSTRACT_PUBMED_11844799}}, adds the Publication Abstract to the page
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Check<jmol>
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(as it appears on PubMed at http://www.pubmed.gov), where 11844799 is the PubMed ID number.
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<jmolCheckbox>
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<scriptWhenChecked>; select protein; define ~consurf_to_do selected; consurf_initial_scene = true; script "/wiki/ConSurf/ko/1kor_consurf.spt"</scriptWhenChecked>
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{{ABSTRACT_PUBMED_11844799}}
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<scriptWhenUnchecked>script /wiki/extensions/Proteopedia/spt/initialview01.spt</scriptWhenUnchecked>
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<text>to colour the structure by Evolutionary Conservation</text>
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==About this Structure==
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</jmolCheckbox>
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1KOR is a [[Single protein]] structure of sequence from [http://en.wikipedia.org/wiki/Thermus_thermophilus Thermus thermophilus]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=1KOR OCA].
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</jmol>, as determined by [http://consurfdb.tau.ac.il/ ConSurfDB]. You may read the [[Conservation%2C_Evolutionary|explanation]] of the method and the full data available from [http://bental.tau.ac.il/new_ConSurfDB/main_output.php?pdb_ID=1kor ConSurf].
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<div style="clear:both"></div>
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==Reference==
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__TOC__
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Crystal structure of argininosuccinate synthetase from Thermus thermophilus HB8. Structural basis for the catalytic action., Goto M, Nakajima Y, Hirotsu K, J Biol Chem. 2002 May 3;277(18):15890-6. Epub 2002 Feb 13. PMID:[http://www.ncbi.nlm.nih.gov/pubmed/11844799 11844799]
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</StructureSection>
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[[Category: Argininosuccinate synthase]]
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[[Category: Large Structures]]
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[[Category: Single protein]]
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[[Category: Thermus thermophilus]]
[[Category: Thermus thermophilus]]
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[[Category: Goto, M.]]
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[[Category: Goto M]]
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[[Category: Hirotsu, K.]]
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[[Category: Hirotsu K]]
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[[Category: Nakajima, Y.]]
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[[Category: Nakajima Y]]
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[[Category: RSGI, RIKEN Structural Genomics/Proteomics Initiative.]]
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[[Category: Ligase]]
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[[Category: Riken structural genomics/proteomics initiative]]
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[[Category: Rsgi]]
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[[Category: Structural genomic]]
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''Page seeded by [http://oca.weizmann.ac.il/oca OCA ] on Wed Jul 2 10:40:26 2008''
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Current revision

Crystal Structure of Thermus thermophilus HB8 Argininosuccinate Synthetase in complex with inhibitors

PDB ID 1kor

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