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1kqc

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{{Seed}}
 
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[[Image:1kqc.png|left|200px]]
 
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==Structure of Nitroreductase from E. cloacae Complex with Inhibitor Acetate==
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The line below this paragraph, containing "STRUCTURE_1kqc", creates the "Structure Box" on the page.
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<StructureSection load='1kqc' size='340' side='right'caption='[[1kqc]], [[Resolution|resolution]] 1.80&Aring;' scene=''>
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You may change the PDB parameter (which sets the PDB file loaded into the applet)
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== Structural highlights ==
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or the SCENE parameter (which sets the initial scene displayed when the page is loaded),
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<table><tr><td colspan='2'>[[1kqc]] is a 4 chain structure with sequence from [https://en.wikipedia.org/wiki/Enterobacter_cloacae Enterobacter cloacae]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=1KQC OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=1KQC FirstGlance]. <br>
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or leave the SCENE parameter empty for the default display.
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</td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models|Method:]]</b></td><td class="sblockDat" id="methodDat">X-ray diffraction, [[Resolution|Resolution]] 1.8&#8491;</td></tr>
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<tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=ACT:ACETATE+ION'>ACT</scene>, <scene name='pdbligand=FMN:FLAVIN+MONONUCLEOTIDE'>FMN</scene></td></tr>
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{{STRUCTURE_1kqc| PDB=1kqc | SCENE= }}
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<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=1kqc FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=1kqc OCA], [https://pdbe.org/1kqc PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=1kqc RCSB], [https://www.ebi.ac.uk/pdbsum/1kqc PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=1kqc ProSAT]</span></td></tr>
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</table>
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== Function ==
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[https://www.uniprot.org/uniprot/NFSB_ENTCL NFSB_ENTCL] Reduction of a variety of nitroaromatic compounds using NADH (and to lesser extent NADPH) as source of reducing equivalents; two electrons are transferred.
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== Evolutionary Conservation ==
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[[Image:Consurf_key_small.gif|200px|right]]
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Check<jmol>
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<jmolCheckbox>
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<scriptWhenChecked>; select protein; define ~consurf_to_do selected; consurf_initial_scene = true; script "/wiki/ConSurf/kq/1kqc_consurf.spt"</scriptWhenChecked>
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<scriptWhenUnchecked>script /wiki/extensions/Proteopedia/spt/initialview01.spt</scriptWhenUnchecked>
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<text>to colour the structure by Evolutionary Conservation</text>
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</jmolCheckbox>
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</jmol>, as determined by [http://consurfdb.tau.ac.il/ ConSurfDB]. You may read the [[Conservation%2C_Evolutionary|explanation]] of the method and the full data available from [http://bental.tau.ac.il/new_ConSurfDB/main_output.php?pdb_ID=1kqc ConSurf].
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<div style="clear:both"></div>
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===Structure of Nitroreductase from E. cloacae Complex with Inhibitor Acetate===
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==See Also==
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*[[Nitroreductase 3D structures|Nitroreductase 3D structures]]
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__TOC__
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</StructureSection>
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The line below this paragraph, {{ABSTRACT_PUBMED_11805110}}, adds the Publication Abstract to the page
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(as it appears on PubMed at http://www.pubmed.gov), where 11805110 is the PubMed ID number.
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{{ABSTRACT_PUBMED_11805110}}
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==About this Structure==
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1KQC is a [[Single protein]] structure of sequence from [http://en.wikipedia.org/wiki/Enterobacter_cloacae Enterobacter cloacae]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=1KQC OCA].
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==Reference==
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Structures of nitroreductase in three states: effects of inhibitor binding and reduction., Haynes CA, Koder RL, Miller AF, Rodgers DW, J Biol Chem. 2002 Mar 29;277(13):11513-20. Epub 2002 Jan 22. PMID:[http://www.ncbi.nlm.nih.gov/pubmed/11805110 11805110]
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[[Category: Enterobacter cloacae]]
[[Category: Enterobacter cloacae]]
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[[Category: Single protein]]
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[[Category: Large Structures]]
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[[Category: Haynes, C A.]]
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[[Category: Haynes CA]]
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[[Category: Koder, R L.]]
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[[Category: Koder RL]]
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[[Category: Miller, A F.]]
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[[Category: Miller AF]]
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[[Category: Rodgers, D W.]]
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[[Category: Rodgers DW]]
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[[Category: Acetate]]
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[[Category: Flavin]]
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[[Category: Nitroreductase]]
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''Page seeded by [http://oca.weizmann.ac.il/oca OCA ] on Wed Jul 2 10:45:43 2008''
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Current revision

Structure of Nitroreductase from E. cloacae Complex with Inhibitor Acetate

PDB ID 1kqc

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