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1ku6

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{{Seed}}
 
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[[Image:1ku6.png|left|200px]]
 
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==Fasciculin 2-Mouse Acetylcholinesterase Complex==
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The line below this paragraph, containing "STRUCTURE_1ku6", creates the "Structure Box" on the page.
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<StructureSection load='1ku6' size='340' side='right'caption='[[1ku6]], [[Resolution|resolution]] 2.50&Aring;' scene=''>
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You may change the PDB parameter (which sets the PDB file loaded into the applet)
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== Structural highlights ==
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or the SCENE parameter (which sets the initial scene displayed when the page is loaded),
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<table><tr><td colspan='2'>[[1ku6]] is a 2 chain structure with sequence from [https://en.wikipedia.org/wiki/Dendroaspis_angusticeps Dendroaspis angusticeps] and [https://en.wikipedia.org/wiki/Mus_musculus Mus musculus]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=1KU6 OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=1KU6 FirstGlance]. <br>
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</td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models|Method:]]</b></td><td class="sblockDat" id="methodDat">X-ray diffraction, [[Resolution|Resolution]] 2.5&#8491;</td></tr>
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<tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=EDO:1,2-ETHANEDIOL'>EDO</scene>, <scene name='pdbligand=NAG:N-ACETYL-D-GLUCOSAMINE'>NAG</scene></td></tr>
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{{STRUCTURE_1ku6| PDB=1ku6 | SCENE= }}
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<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=1ku6 FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=1ku6 OCA], [https://pdbe.org/1ku6 PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=1ku6 RCSB], [https://www.ebi.ac.uk/pdbsum/1ku6 PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=1ku6 ProSAT]</span></td></tr>
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</table>
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== Function ==
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[https://www.uniprot.org/uniprot/ACES_MOUSE ACES_MOUSE] Terminates signal transduction at the neuromuscular junction by rapid hydrolysis of the acetylcholine released into the synaptic cleft.
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== Evolutionary Conservation ==
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[[Image:Consurf_key_small.gif|200px|right]]
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Check<jmol>
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<jmolCheckbox>
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<scriptWhenChecked>; select protein; define ~consurf_to_do selected; consurf_initial_scene = true; script "/wiki/ConSurf/ku/1ku6_consurf.spt"</scriptWhenChecked>
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<scriptWhenUnchecked>script /wiki/extensions/Proteopedia/spt/initialview01.spt</scriptWhenUnchecked>
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<text>to colour the structure by Evolutionary Conservation</text>
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</jmolCheckbox>
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</jmol>, as determined by [http://consurfdb.tau.ac.il/ ConSurfDB]. You may read the [[Conservation%2C_Evolutionary|explanation]] of the method and the full data available from [http://bental.tau.ac.il/new_ConSurfDB/main_output.php?pdb_ID=1ku6 ConSurf].
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<div style="clear:both"></div>
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===Fasciculin 2-Mouse Acetylcholinesterase Complex===
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==See Also==
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*[[Acetylcholinesterase 3D structures|Acetylcholinesterase 3D structures]]
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*[[Fasciculin|Fasciculin]]
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__TOC__
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The line below this paragraph, {{ABSTRACT_PUBMED_12505979}}, adds the Publication Abstract to the page
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</StructureSection>
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(as it appears on PubMed at http://www.pubmed.gov), where 12505979 is the PubMed ID number.
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{{ABSTRACT_PUBMED_12505979}}
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==About this Structure==
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1KU6 is a [[Protein complex]] structure of sequences from [http://en.wikipedia.org/wiki/Dendroaspis_angusticeps Dendroaspis angusticeps] and [http://en.wikipedia.org/wiki/Mus_musculus Mus musculus]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=1KU6 OCA].
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==Reference==
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Structural insights into ligand interactions at the acetylcholinesterase peripheral anionic site., Bourne Y, Taylor P, Radic Z, Marchot P, EMBO J. 2003 Jan 2;22(1):1-12. PMID:[http://www.ncbi.nlm.nih.gov/pubmed/12505979 12505979]
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[[Category: Dendroaspis angusticeps]]
[[Category: Dendroaspis angusticeps]]
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[[Category: Large Structures]]
[[Category: Mus musculus]]
[[Category: Mus musculus]]
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[[Category: Protein complex]]
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[[Category: Bourne Y]]
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[[Category: Bourne, Y.]]
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[[Category: Burmeister W]]
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[[Category: Burmeister, W.]]
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[[Category: Marchot P]]
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[[Category: Marchot, P.]]
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[[Category: Taylor P]]
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[[Category: Taylor, P.]]
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[[Category: Hydrolase]]
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[[Category: Serine esterase]]
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[[Category: Synapse]]
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[[Category: Toxin]]
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[[Category: Venom]]
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''Page seeded by [http://oca.weizmann.ac.il/oca OCA ] on Wed Jul 2 11:00:42 2008''
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Current revision

Fasciculin 2-Mouse Acetylcholinesterase Complex

PDB ID 1ku6

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