1kzl

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{{Seed}}
 
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[[Image:1kzl.png|left|200px]]
 
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<!--
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==Riboflavin Synthase from S.pombe bound to Carboxyethyllumazine==
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The line below this paragraph, containing "STRUCTURE_1kzl", creates the "Structure Box" on the page.
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<StructureSection load='1kzl' size='340' side='right'caption='[[1kzl]], [[Resolution|resolution]] 2.10&Aring;' scene=''>
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You may change the PDB parameter (which sets the PDB file loaded into the applet)
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== Structural highlights ==
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or the SCENE parameter (which sets the initial scene displayed when the page is loaded),
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<table><tr><td colspan='2'>[[1kzl]] is a 1 chain structure with sequence from [https://en.wikipedia.org/wiki/Schizosaccharomyces_pombe Schizosaccharomyces pombe]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=1KZL OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=1KZL FirstGlance]. <br>
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or leave the SCENE parameter empty for the default display.
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</td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models|Method:]]</b></td><td class="sblockDat" id="methodDat">X-ray diffraction, [[Resolution|Resolution]] 2.1&#8491;</td></tr>
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<tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=CRM:3-[8-((2S,3S,4R)-2,3,4,5-TETRAHYDROXYPENTYL)-2,4,7-TRIOXO-1,3,8-TRIHYDROPTERIDIN-6-YL]PROPANOIC+ACID'>CRM</scene>, <scene name='pdbligand=HG:MERCURY+(II)+ION'>HG</scene></td></tr>
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{{STRUCTURE_1kzl| PDB=1kzl | SCENE= }}
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<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=1kzl FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=1kzl OCA], [https://pdbe.org/1kzl PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=1kzl RCSB], [https://www.ebi.ac.uk/pdbsum/1kzl PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=1kzl ProSAT]</span></td></tr>
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</table>
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===Riboflavin Synthase from S.pombe bound to Carboxyethyllumazine===
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== Function ==
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[https://www.uniprot.org/uniprot/RISA_SCHPO RISA_SCHPO] Catalyzes the dismutation of two molecules of 6,7-dimethyl-8-ribityllumazine, resulting in the formation of riboflavin and 5-amino-6-(D-ribitylamino)uracil.
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== Evolutionary Conservation ==
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[[Image:Consurf_key_small.gif|200px|right]]
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The line below this paragraph, {{ABSTRACT_PUBMED_12377123}}, adds the Publication Abstract to the page
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Check<jmol>
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(as it appears on PubMed at http://www.pubmed.gov), where 12377123 is the PubMed ID number.
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<jmolCheckbox>
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<scriptWhenChecked>; select protein; define ~consurf_to_do selected; consurf_initial_scene = true; script "/wiki/ConSurf/kz/1kzl_consurf.spt"</scriptWhenChecked>
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{{ABSTRACT_PUBMED_12377123}}
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<scriptWhenUnchecked>script /wiki/extensions/Proteopedia/spt/initialview01.spt</scriptWhenUnchecked>
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<text>to colour the structure by Evolutionary Conservation</text>
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==About this Structure==
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</jmolCheckbox>
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1KZL is a [[Single protein]] structure of sequence from [http://en.wikipedia.org/wiki/Schizosaccharomyces_pombe Schizosaccharomyces pombe]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=1KZL OCA].
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</jmol>, as determined by [http://consurfdb.tau.ac.il/ ConSurfDB]. You may read the [[Conservation%2C_Evolutionary|explanation]] of the method and the full data available from [http://bental.tau.ac.il/new_ConSurfDB/main_output.php?pdb_ID=1kzl ConSurf].
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<div style="clear:both"></div>
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==Reference==
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__TOC__
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Studies on the reaction mechanism of riboflavin synthase: X-ray crystal structure of a complex with 6-carboxyethyl-7-oxo-8-ribityllumazine., Gerhardt S, Schott AK, Kairies N, Cushman M, Illarionov B, Eisenreich W, Bacher A, Huber R, Steinbacher S, Fischer M, Structure. 2002 Oct;10(10):1371-81. PMID:[http://www.ncbi.nlm.nih.gov/pubmed/12377123 12377123]
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</StructureSection>
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[[Category: Riboflavin synthase]]
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[[Category: Large Structures]]
[[Category: Schizosaccharomyces pombe]]
[[Category: Schizosaccharomyces pombe]]
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[[Category: Single protein]]
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[[Category: Bacher A]]
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[[Category: Bacher, A.]]
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[[Category: Cushman M]]
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[[Category: Cushman, M.]]
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[[Category: Eisenreich W]]
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[[Category: Eisenreich, W.]]
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[[Category: Fischer M]]
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[[Category: Fischer, M.]]
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[[Category: Gerhardt S]]
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[[Category: Gerhardt, S.]]
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[[Category: Huber R]]
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[[Category: Huber, R.]]
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[[Category: Illarionov B]]
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[[Category: Illarionov, B.]]
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[[Category: Kairies N]]
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[[Category: Kairies, N.]]
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[[Category: Schott AK]]
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[[Category: Schott, A K.]]
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[[Category: Steinbacher S]]
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[[Category: Steinbacher, S.]]
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[[Category: Biosynthesis of riboflavin]]
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[[Category: Ligand binding]]
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[[Category: Riboflavin synthase]]
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[[Category: Schizosaccharomyces pombe]]
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[[Category: X-ray structure]]
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''Page seeded by [http://oca.weizmann.ac.il/oca OCA ] on Wed Jul 2 11:22:13 2008''
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Current revision

Riboflavin Synthase from S.pombe bound to Carboxyethyllumazine

PDB ID 1kzl

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