1l2l

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{{Seed}}
 
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[[Image:1l2l.png|left|200px]]
 
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==Crystal structure of ADP-dependent glucokinase from a Pyrococcus Horikoshii==
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The line below this paragraph, containing "STRUCTURE_1l2l", creates the "Structure Box" on the page.
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<StructureSection load='1l2l' size='340' side='right'caption='[[1l2l]], [[Resolution|resolution]] 2.00&Aring;' scene=''>
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You may change the PDB parameter (which sets the PDB file loaded into the applet)
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== Structural highlights ==
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or the SCENE parameter (which sets the initial scene displayed when the page is loaded),
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<table><tr><td colspan='2'>[[1l2l]] is a 1 chain structure with sequence from [https://en.wikipedia.org/wiki/Pyrococcus_horikoshii Pyrococcus horikoshii]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=1L2L OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=1L2L FirstGlance]. <br>
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or leave the SCENE parameter empty for the default display.
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</td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models|Method:]]</b></td><td class="sblockDat" id="methodDat">X-ray diffraction, [[Resolution|Resolution]] 2&#8491;</td></tr>
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<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=1l2l FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=1l2l OCA], [https://pdbe.org/1l2l PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=1l2l RCSB], [https://www.ebi.ac.uk/pdbsum/1l2l PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=1l2l ProSAT]</span></td></tr>
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{{STRUCTURE_1l2l| PDB=1l2l | SCENE= }}
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</table>
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== Function ==
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[https://www.uniprot.org/uniprot/GLKA_PYRHO GLKA_PYRHO] Catalyzes the phosphorylation of D-glucose to D-glucose 6-phosphate using ADP as the phosphate donor.
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== Evolutionary Conservation ==
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[[Image:Consurf_key_small.gif|200px|right]]
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Check<jmol>
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<jmolCheckbox>
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<scriptWhenChecked>; select protein; define ~consurf_to_do selected; consurf_initial_scene = true; script "/wiki/ConSurf/l2/1l2l_consurf.spt"</scriptWhenChecked>
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<scriptWhenUnchecked>script /wiki/extensions/Proteopedia/spt/initialview01.spt</scriptWhenUnchecked>
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<text>to colour the structure by Evolutionary Conservation</text>
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</jmolCheckbox>
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</jmol>, as determined by [http://consurfdb.tau.ac.il/ ConSurfDB]. You may read the [[Conservation%2C_Evolutionary|explanation]] of the method and the full data available from [http://bental.tau.ac.il/new_ConSurfDB/main_output.php?pdb_ID=1l2l ConSurf].
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<div style="clear:both"></div>
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===Crystal structure of ADP-dependent glucokinase from a Pyrococcus Horikoshii===
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==See Also==
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*[[Hexokinase 3D structures|Hexokinase 3D structures]]
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__TOC__
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</StructureSection>
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The line below this paragraph, {{ABSTRACT_PUBMED_12237466}}, adds the Publication Abstract to the page
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[[Category: Large Structures]]
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(as it appears on PubMed at http://www.pubmed.gov), where 12237466 is the PubMed ID number.
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{{ABSTRACT_PUBMED_12237466}}
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==About this Structure==
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1L2L is a [[Single protein]] structure of sequence from [http://en.wikipedia.org/wiki/Pyrococcus_horikoshii Pyrococcus horikoshii]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=1L2L OCA].
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==Reference==
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Crystal structure of the ADP-dependent glucokinase from Pyrococcus horikoshii at 2.0-A resolution: a large conformational change in ADP-dependent glucokinase., Tsuge H, Sakuraba H, Kobe T, Kujime A, Katunuma N, Ohshima T, Protein Sci. 2002 Oct;11(10):2456-63. PMID:[http://www.ncbi.nlm.nih.gov/pubmed/12237466 12237466]
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[[Category: Glucokinase]]
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[[Category: Pyrococcus horikoshii]]
[[Category: Pyrococcus horikoshii]]
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[[Category: Single protein]]
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[[Category: Katunuma N]]
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[[Category: Katunuma, N.]]
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[[Category: Ohshima T]]
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[[Category: Ohshima, T.]]
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[[Category: Sakuraba H]]
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[[Category: Sakuraba, H.]]
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[[Category: Tsuge H]]
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[[Category: Tsuge, H.]]
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[[Category: Adp glucokinase apo]]
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''Page seeded by [http://oca.weizmann.ac.il/oca OCA ] on Wed Jul 2 11:33:39 2008''
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Current revision

Crystal structure of ADP-dependent glucokinase from a Pyrococcus Horikoshii

PDB ID 1l2l

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