1lbg

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{{Seed}}
 
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[[Image:1lbg.png|left|200px]]
 
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==LACTOSE OPERON REPRESSOR BOUND TO 21-BASE PAIR SYMMETRIC OPERATOR DNA, ALPHA CARBONS ONLY==
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The line below this paragraph, containing "STRUCTURE_1lbg", creates the "Structure Box" on the page.
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<StructureSection load='1lbg' size='340' side='right'caption='[[1lbg]], [[Resolution|resolution]] 4.80&Aring;' scene=''>
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You may change the PDB parameter (which sets the PDB file loaded into the applet)
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== Structural highlights ==
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or the SCENE parameter (which sets the initial scene displayed when the page is loaded),
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<table><tr><td colspan='2'>[[1lbg]] is a 8 chain structure with sequence from [https://en.wikipedia.org/wiki/Escherichia_coli Escherichia coli]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=1LBG OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=1LBG FirstGlance]. <br>
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or leave the SCENE parameter empty for the default display.
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</td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models|Method:]]</b></td><td class="sblockDat" id="methodDat">X-ray diffraction, [[Resolution|Resolution]] 4.8&#8491;</td></tr>
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<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=1lbg FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=1lbg OCA], [https://pdbe.org/1lbg PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=1lbg RCSB], [https://www.ebi.ac.uk/pdbsum/1lbg PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=1lbg ProSAT]</span></td></tr>
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{{STRUCTURE_1lbg| PDB=1lbg | SCENE= }}
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</table>
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== Function ==
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[https://www.uniprot.org/uniprot/LACI_ECOLI LACI_ECOLI] Repressor of the lactose operon. Binds allolactose as an inducer.
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== Evolutionary Conservation ==
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[[Image:Consurf_key_small.gif|200px|right]]
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Check<jmol>
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<jmolCheckbox>
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<scriptWhenChecked>; select protein; define ~consurf_to_do selected; consurf_initial_scene = true; script "/wiki/ConSurf/lb/1lbg_consurf.spt"</scriptWhenChecked>
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<scriptWhenUnchecked>script /wiki/extensions/Proteopedia/spt/initialview01.spt</scriptWhenUnchecked>
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<text>to colour the structure by Evolutionary Conservation</text>
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</jmolCheckbox>
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</jmol>, as determined by [http://consurfdb.tau.ac.il/ ConSurfDB]. You may read the [[Conservation%2C_Evolutionary|explanation]] of the method and the full data available from [http://bental.tau.ac.il/new_ConSurfDB/main_output.php?pdb_ID=1lbg ConSurf].
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<div style="clear:both"></div>
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===LACTOSE OPERON REPRESSOR BOUND TO 21-BASE PAIR SYMMETRIC OPERATOR DNA, ALPHA CARBONS ONLY===
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==See Also==
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*[[Lac repressor|Lac repressor]]
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__TOC__
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</StructureSection>
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The line below this paragraph, {{ABSTRACT_PUBMED_8638105}}, adds the Publication Abstract to the page
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(as it appears on PubMed at http://www.pubmed.gov), where 8638105 is the PubMed ID number.
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{{ABSTRACT_PUBMED_8638105}}
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==About this Structure==
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1LBG is a [[Single protein]] structure of sequence from [http://en.wikipedia.org/wiki/Escherichia_coli Escherichia coli]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=1LBG OCA].
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==Reference==
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Crystal structure of the lactose operon repressor and its complexes with DNA and inducer., Lewis M, Chang G, Horton NC, Kercher MA, Pace HC, Schumacher MA, Brennan RG, Lu P, Science. 1996 Mar 1;271(5253):1247-54. PMID:[http://www.ncbi.nlm.nih.gov/pubmed/8638105 8638105]
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[[Category: Escherichia coli]]
[[Category: Escherichia coli]]
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[[Category: Single protein]]
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[[Category: Large Structures]]
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[[Category: Chang, G.]]
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[[Category: Chang G]]
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[[Category: Horton, N C.]]
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[[Category: Horton NC]]
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[[Category: Kercher, M A.]]
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[[Category: Kercher MA]]
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[[Category: Lewis, M.]]
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[[Category: Lewis M]]
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[[Category: Lu, P.]]
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[[Category: Lu P]]
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[[Category: Pace, H C.]]
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[[Category: Pace HC]]
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[[Category: Dna-binding]]
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[[Category: Repressor]]
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[[Category: Transcription regulation]]
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''Page seeded by [http://oca.weizmann.ac.il/oca OCA ] on Wed Jul 2 12:14:32 2008''
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Current revision

LACTOSE OPERON REPRESSOR BOUND TO 21-BASE PAIR SYMMETRIC OPERATOR DNA, ALPHA CARBONS ONLY

PDB ID 1lbg

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