This old version of Proteopedia is provided for student assignments while the new version is undergoing repairs. Content and edits done in this old version of Proteopedia after March 1, 2026 will eventually be lost when it is retired in about June of 2026.

Apply for new accounts at the new Proteopedia. Your logins will work in both the old and new versions.


1lc0

From Proteopedia

(Difference between revisions)
Jump to: navigation, search
Current revision (07:31, 14 February 2024) (edit) (undo)
 
(10 intermediate revisions not shown.)
Line 1: Line 1:
-
{{Seed}}
 
-
[[Image:1lc0.png|left|200px]]
 
-
<!--
+
==Structure of Biliverdin Reductase and the Enzyme-NADH Complex==
-
The line below this paragraph, containing "STRUCTURE_1lc0", creates the "Structure Box" on the page.
+
<StructureSection load='1lc0' size='340' side='right'caption='[[1lc0]], [[Resolution|resolution]] 1.20&Aring;' scene=''>
-
You may change the PDB parameter (which sets the PDB file loaded into the applet)
+
== Structural highlights ==
-
or the SCENE parameter (which sets the initial scene displayed when the page is loaded),
+
<table><tr><td colspan='2'>[[1lc0]] is a 1 chain structure with sequence from [https://en.wikipedia.org/wiki/Rattus_norvegicus Rattus norvegicus]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=1LC0 OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=1LC0 FirstGlance]. <br>
-
or leave the SCENE parameter empty for the default display.
+
</td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models|Method:]]</b></td><td class="sblockDat" id="methodDat">X-ray diffraction, [[Resolution|Resolution]] 1.2&#8491;</td></tr>
-
-->
+
<tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=PO4:PHOSPHATE+ION'>PO4</scene></td></tr>
-
{{STRUCTURE_1lc0| PDB=1lc0 | SCENE= }}
+
<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=1lc0 FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=1lc0 OCA], [https://pdbe.org/1lc0 PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=1lc0 RCSB], [https://www.ebi.ac.uk/pdbsum/1lc0 PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=1lc0 ProSAT]</span></td></tr>
-
 
+
</table>
-
===Structure of Biliverdin Reductase and the Enzyme-NADH Complex===
+
== Function ==
-
 
+
[https://www.uniprot.org/uniprot/BIEA_RAT BIEA_RAT] Reduces the gamma-methene bridge of the open tetrapyrrole, biliverdin IX alpha, to bilirubin with the concomitant oxidation of a NADH or NADPH cofactor.
-
 
+
== Evolutionary Conservation ==
-
<!--
+
[[Image:Consurf_key_small.gif|200px|right]]
-
The line below this paragraph, {{ABSTRACT_PUBMED_12079357}}, adds the Publication Abstract to the page
+
Check<jmol>
-
(as it appears on PubMed at http://www.pubmed.gov), where 12079357 is the PubMed ID number.
+
<jmolCheckbox>
-
-->
+
<scriptWhenChecked>; select protein; define ~consurf_to_do selected; consurf_initial_scene = true; script "/wiki/ConSurf/lc/1lc0_consurf.spt"</scriptWhenChecked>
-
{{ABSTRACT_PUBMED_12079357}}
+
<scriptWhenUnchecked>script /wiki/extensions/Proteopedia/spt/initialview01.spt</scriptWhenUnchecked>
-
 
+
<text>to colour the structure by Evolutionary Conservation</text>
-
==About this Structure==
+
</jmolCheckbox>
-
1LC0 is a [[Single protein]] structure of sequence from [http://en.wikipedia.org/wiki/Rattus_norvegicus Rattus norvegicus]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=1LC0 OCA].
+
</jmol>, as determined by [http://consurfdb.tau.ac.il/ ConSurfDB]. You may read the [[Conservation%2C_Evolutionary|explanation]] of the method and the full data available from [http://bental.tau.ac.il/new_ConSurfDB/main_output.php?pdb_ID=1lc0 ConSurf].
-
 
+
<div style="clear:both"></div>
-
==Reference==
+
__TOC__
-
Crystal structure of a biliverdin IXalpha reductase enzyme-cofactor complex., Whitby FG, Phillips JD, Hill CP, McCoubrey W, Maines MD, J Mol Biol. 2002 Jun 21;319(5):1199-210. PMID:[http://www.ncbi.nlm.nih.gov/pubmed/12079357 12079357]
+
</StructureSection>
-
[[Category: Biliverdin reductase]]
+
[[Category: Large Structures]]
[[Category: Rattus norvegicus]]
[[Category: Rattus norvegicus]]
-
[[Category: Single protein]]
+
[[Category: Hill CP]]
-
[[Category: Hill, C P.]]
+
[[Category: Maines MD]]
-
[[Category: Maines, M D.]]
+
[[Category: McCoubrey W]]
-
[[Category: McCoubrey, W.]]
+
[[Category: Phillips JD]]
-
[[Category: Phillips, J D.]]
+
[[Category: Whitby FG]]
-
[[Category: Whitby, F G.]]
+
-
[[Category: Bile pigment]]
+
-
[[Category: Bilirubin]]
+
-
[[Category: Biliverdin reductase]]
+
-
[[Category: Heme]]
+
-
[[Category: Nadh]]
+
-
[[Category: Oxidoreductase]]
+
-
[[Category: Tetrapyrrole]]
+
-
 
+
-
''Page seeded by [http://oca.weizmann.ac.il/oca OCA ] on Wed Jul 2 12:18:10 2008''
+

Current revision

Structure of Biliverdin Reductase and the Enzyme-NADH Complex

PDB ID 1lc0

Drag the structure with the mouse to rotate

Proteopedia Page Contributors and Editors (what is this?)

OCA

Retrieved from "http://52.214.119.220/wiki/index.php/1lc0"
Personal tools