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1ldg

From Proteopedia

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{{Seed}}
 
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[[Image:1ldg.png|left|200px]]
 
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==PLASMODIUM FALCIPARUM L-LACTATE DEHYDROGENASE COMPLEXED WITH NADH AND OXAMATE==
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The line below this paragraph, containing "STRUCTURE_1ldg", creates the "Structure Box" on the page.
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<StructureSection load='1ldg' size='340' side='right'caption='[[1ldg]], [[Resolution|resolution]] 1.74&Aring;' scene=''>
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You may change the PDB parameter (which sets the PDB file loaded into the applet)
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== Structural highlights ==
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or the SCENE parameter (which sets the initial scene displayed when the page is loaded),
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<table><tr><td colspan='2'>[[1ldg]] is a 1 chain structure with sequence from [https://en.wikipedia.org/wiki/Plasmodium_falciparum Plasmodium falciparum]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=1LDG OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=1LDG FirstGlance]. <br>
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or leave the SCENE parameter empty for the default display.
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</td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models|Method:]]</b></td><td class="sblockDat" id="methodDat">X-ray diffraction, [[Resolution|Resolution]] 1.74&#8491;</td></tr>
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<tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=NAI:1,4-DIHYDRONICOTINAMIDE+ADENINE+DINUCLEOTIDE'>NAI</scene>, <scene name='pdbligand=OXM:OXAMIC+ACID'>OXM</scene></td></tr>
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{{STRUCTURE_1ldg| PDB=1ldg | SCENE= }}
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<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=1ldg FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=1ldg OCA], [https://pdbe.org/1ldg PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=1ldg RCSB], [https://www.ebi.ac.uk/pdbsum/1ldg PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=1ldg ProSAT]</span></td></tr>
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</table>
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== Function ==
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[https://www.uniprot.org/uniprot/LDH_PLAFD LDH_PLAFD]
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== Evolutionary Conservation ==
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[[Image:Consurf_key_small.gif|200px|right]]
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Check<jmol>
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<jmolCheckbox>
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<scriptWhenChecked>; select protein; define ~consurf_to_do selected; consurf_initial_scene = true; script "/wiki/ConSurf/ld/1ldg_consurf.spt"</scriptWhenChecked>
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<scriptWhenUnchecked>script /wiki/extensions/Proteopedia/spt/initialview01.spt</scriptWhenUnchecked>
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<text>to colour the structure by Evolutionary Conservation</text>
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</jmolCheckbox>
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</jmol>, as determined by [http://consurfdb.tau.ac.il/ ConSurfDB]. You may read the [[Conservation%2C_Evolutionary|explanation]] of the method and the full data available from [http://bental.tau.ac.il/new_ConSurfDB/main_output.php?pdb_ID=1ldg ConSurf].
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<div style="clear:both"></div>
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===PLASMODIUM FALCIPARUM L-LACTATE DEHYDROGENASE COMPLEXED WITH NADH AND OXAMATE===
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==See Also==
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*[[Lactate dehydrogenase 3D structures|Lactate dehydrogenase 3D structures]]
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__TOC__
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==About this Structure==
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</StructureSection>
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1LDG is a [[Single protein]] structure of sequence from [http://en.wikipedia.org/wiki/Plasmodium_falciparum Plasmodium falciparum]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=1LDG OCA].
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[[Category: Large Structures]]
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==Reference==
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The structure of lactate dehydrogenase from Plasmodium falciparum reveals a new target for anti-malarial design., Dunn CR, Banfield MJ, Barker JJ, Higham CW, Moreton KM, Turgut-Balik D, Brady RL, Holbrook JJ, Nat Struct Biol. 1996 Nov;3(11):912-5. PMID:[http://www.ncbi.nlm.nih.gov/pubmed/8901865 8901865]
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[[Category: L-lactate dehydrogenase]]
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[[Category: Plasmodium falciparum]]
[[Category: Plasmodium falciparum]]
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[[Category: Single protein]]
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[[Category: Banfield M]]
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[[Category: Banfield, M.]]
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[[Category: Barker J]]
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[[Category: Barker, J.]]
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[[Category: Brady L]]
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[[Category: Brady, L.]]
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[[Category: Dunn C]]
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[[Category: Dunn, C.]]
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[[Category: Higham C]]
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[[Category: Higham, C.]]
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[[Category: Holbrook JJ]]
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[[Category: Holbrook, J J.]]
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[[Category: Moreton K]]
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[[Category: Moreton, K.]]
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[[Category: Turgut-Balik D]]
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[[Category: Turgut-Balik, D.]]
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[[Category: Nad]]
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[[Category: Oxidoreductase]]
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[[Category: Tricarboxylic acid cycle]]
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''Page seeded by [http://oca.weizmann.ac.il/oca OCA ] on Wed Jul 2 12:32:36 2008''
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Current revision

PLASMODIUM FALCIPARUM L-LACTATE DEHYDROGENASE COMPLEXED WITH NADH AND OXAMATE

PDB ID 1ldg

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