2q18

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{{Seed}}
 
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[[Image:2q18.png|left|200px]]
 
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==2-keto-3-deoxy-D-arabinonate dehydratase==
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The line below this paragraph, containing "STRUCTURE_2q18", creates the "Structure Box" on the page.
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<StructureSection load='2q18' size='340' side='right'caption='[[2q18]], [[Resolution|resolution]] 2.10&Aring;' scene=''>
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You may change the PDB parameter (which sets the PDB file loaded into the applet)
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== Structural highlights ==
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or the SCENE parameter (which sets the initial scene displayed when the page is loaded),
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<table><tr><td colspan='2'>[[2q18]] is a 1 chain structure with sequence from [https://en.wikipedia.org/wiki/Saccharolobus_solfataricus_P2 Saccharolobus solfataricus P2]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=2Q18 OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=2Q18 FirstGlance]. <br>
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or leave the SCENE parameter empty for the default display.
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</td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models|Method:]]</b></td><td class="sblockDat" id="methodDat">X-ray diffraction, [[Resolution|Resolution]] 2.1&#8491;</td></tr>
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<tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=PO4:PHOSPHATE+ION'>PO4</scene></td></tr>
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{{STRUCTURE_2q18| PDB=2q18 | SCENE= }}
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<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=2q18 FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=2q18 OCA], [https://pdbe.org/2q18 PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=2q18 RCSB], [https://www.ebi.ac.uk/pdbsum/2q18 PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=2q18 ProSAT]</span></td></tr>
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</table>
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===2-keto-3-deoxy-D-arabinonate dehydratase===
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== Function ==
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[https://www.uniprot.org/uniprot/KDAD_SACS2 KDAD_SACS2] Participates in a pentose oxidation pathway that converts D-arabinonate to 2-oxoglutarate.<ref>PMID:16849334</ref>
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== Evolutionary Conservation ==
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[[Image:Consurf_key_small.gif|200px|right]]
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Check<jmol>
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(as it appears on PubMed at http://www.pubmed.gov), where 18448118 is the PubMed ID number.
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<jmolCheckbox>
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<scriptWhenChecked>; select protein; define ~consurf_to_do selected; consurf_initial_scene = true; script "/wiki/ConSurf/q1/2q18_consurf.spt"</scriptWhenChecked>
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{{ABSTRACT_PUBMED_18448118}}
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<scriptWhenUnchecked>script /wiki/extensions/Proteopedia/spt/initialview01.spt</scriptWhenUnchecked>
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<text>to colour the structure by Evolutionary Conservation</text>
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==About this Structure==
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</jmolCheckbox>
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2Q18 is a [[Single protein]] structure of sequence from [http://en.wikipedia.org/wiki/Sulfolobus_solfataricus_p2 Sulfolobus solfataricus p2]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=2Q18 OCA].
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</jmol>, as determined by [http://consurfdb.tau.ac.il/ ConSurfDB]. You may read the [[Conservation%2C_Evolutionary|explanation]] of the method and the full data available from [http://bental.tau.ac.il/new_ConSurfDB/main_output.php?pdb_ID=2q18 ConSurf].
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<div style="clear:both"></div>
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==Reference==
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== References ==
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Structural insight into substrate binding and catalysis of a novel 2-keto-3-deoxy-D-arabinonate dehydratase illustrates common mechanistic features of the FAH superfamily., Brouns SJ, Barends TR, Worm P, Akerboom J, Turnbull AP, Salmon L, van der Oost J, J Mol Biol. 2008 May 30;379(2):357-71. Epub 2008 Apr 8. PMID:[http://www.ncbi.nlm.nih.gov/pubmed/18448118 18448118]
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<references/>
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[[Category: Single protein]]
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__TOC__
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[[Category: Sulfolobus solfataricus p2]]
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</StructureSection>
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[[Category: Akerboom, J]]
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[[Category: Large Structures]]
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[[Category: Barends, T.]]
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[[Category: Saccharolobus solfataricus P2]]
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[[Category: Brouns, S.]]
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[[Category: Akerboom J]]
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[[Category: Salmon, L.]]
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[[Category: Barends T]]
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[[Category: Turnbull, A.]]
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[[Category: Brouns S]]
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[[Category: Worm, P.]]
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[[Category: Salmon L]]
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[[Category: Fah-family fold]]
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[[Category: Turnbull A]]
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[[Category: Lyase]]
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[[Category: Worm P]]
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''Page seeded by [http://oca.weizmann.ac.il/oca OCA ] on Wed Jul 2 21:25:00 2008''
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Current revision

2-keto-3-deoxy-D-arabinonate dehydratase

PDB ID 2q18

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