This old version of Proteopedia is provided for student assignments while the new version is undergoing repairs. Content and edits done in this old version of Proteopedia after March 1, 2026 will eventually be lost when it is retired in about June of 2026.

Apply for new accounts at the new Proteopedia. Your logins will work in both the old and new versions.


1lp8

From Proteopedia

(Difference between revisions)
Jump to: navigation, search
Current revision (07:34, 14 February 2024) (edit) (undo)
 
(10 intermediate revisions not shown.)
Line 1: Line 1:
-
{{Seed}}
 
-
[[Image:1lp8.png|left|200px]]
 
-
<!--
+
==HIGH RESOLUTION STRUCTURE OF RECOMBINANT DIANTHIN ANTIVIRAL PROTEIN-POTENT ANTI-HIV AGENT==
-
The line below this paragraph, containing "STRUCTURE_1lp8", creates the "Structure Box" on the page.
+
<StructureSection load='1lp8' size='340' side='right'caption='[[1lp8]], [[Resolution|resolution]] 1.65&Aring;' scene=''>
-
You may change the PDB parameter (which sets the PDB file loaded into the applet)
+
== Structural highlights ==
-
or the SCENE parameter (which sets the initial scene displayed when the page is loaded),
+
<table><tr><td colspan='2'>[[1lp8]] is a 1 chain structure with sequence from [https://en.wikipedia.org/wiki/Dianthus_caryophyllus Dianthus caryophyllus]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=1LP8 OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=1LP8 FirstGlance]. <br>
-
or leave the SCENE parameter empty for the default display.
+
</td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models|Method:]]</b></td><td class="sblockDat" id="methodDat">X-ray diffraction, [[Resolution|Resolution]] 1.65&#8491;</td></tr>
-
-->
+
<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=1lp8 FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=1lp8 OCA], [https://pdbe.org/1lp8 PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=1lp8 RCSB], [https://www.ebi.ac.uk/pdbsum/1lp8 PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=1lp8 ProSAT]</span></td></tr>
-
{{STRUCTURE_1lp8| PDB=1lp8 | SCENE= }}
+
</table>
 +
== Function ==
 +
[https://www.uniprot.org/uniprot/RIP0_DIACA RIP0_DIACA] Single-chain ribosome-inactivating protein.
 +
== Evolutionary Conservation ==
 +
[[Image:Consurf_key_small.gif|200px|right]]
 +
Check<jmol>
 +
<jmolCheckbox>
 +
<scriptWhenChecked>; select protein; define ~consurf_to_do selected; consurf_initial_scene = true; script "/wiki/ConSurf/lp/1lp8_consurf.spt"</scriptWhenChecked>
 +
<scriptWhenUnchecked>script /wiki/extensions/Proteopedia/spt/initialview01.spt</scriptWhenUnchecked>
 +
<text>to colour the structure by Evolutionary Conservation</text>
 +
</jmolCheckbox>
 +
</jmol>, as determined by [http://consurfdb.tau.ac.il/ ConSurfDB]. You may read the [[Conservation%2C_Evolutionary|explanation]] of the method and the full data available from [http://bental.tau.ac.il/new_ConSurfDB/main_output.php?pdb_ID=1lp8 ConSurf].
 +
<div style="clear:both"></div>
-
===HIGH RESOLUTION STRUCTURE OF RECOMBINANT DIANTHIN ANTIVIRAL PROTEIN-POTENT ANTI-HIV AGENT===
+
==See Also==
-
 
+
*[[Ribosome inactivating protein 3D structures|Ribosome inactivating protein 3D structures]]
-
 
+
__TOC__
-
<!--
+
</StructureSection>
-
The line below this paragraph, {{ABSTRACT_PUBMED_15553110}}, adds the Publication Abstract to the page
+
-
(as it appears on PubMed at http://www.pubmed.gov), where 15553110 is the PubMed ID number.
+
-
-->
+
-
{{ABSTRACT_PUBMED_15553110}}
+
-
 
+
-
==About this Structure==
+
-
1LP8 is a [[Single protein]] structure of sequence from [http://en.wikipedia.org/wiki/Dianthus_caryophyllus Dianthus caryophyllus]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=1LP8 OCA].
+
-
 
+
-
==Reference==
+
-
High resolution X-ray structure and potent anti-HIV activity of recombinant dianthin antiviral protein., Kurinov IV, Rajamohan F, Uckun FM, Arzneimittelforschung. 2004;54(10):692-702. PMID:[http://www.ncbi.nlm.nih.gov/pubmed/15553110 15553110]
+
[[Category: Dianthus caryophyllus]]
[[Category: Dianthus caryophyllus]]
-
[[Category: Single protein]]
+
[[Category: Large Structures]]
-
[[Category: RRNA N-glycosylase]]
+
[[Category: Kurinov IV]]
-
[[Category: Kurinov, I V.]]
+
[[Category: Rajamohan F]]
-
[[Category: Rajamohan, F.]]
+
[[Category: Uckun FM]]
-
[[Category: Uckun, F M.]]
+
-
[[Category: Anti-hiv agent]]
+
-
[[Category: Dianthin antiviral protein]]
+
-
[[Category: Hiv-1 integrase inhibitor]]
+
-
[[Category: Polynucleotide:adenosine glycosidase]]
+
-
[[Category: Ribosome inactivating protein]]
+
-
 
+
-
''Page seeded by [http://oca.weizmann.ac.il/oca OCA ] on Wed Jul 2 21:41:46 2008''
+

Current revision

HIGH RESOLUTION STRUCTURE OF RECOMBINANT DIANTHIN ANTIVIRAL PROTEIN-POTENT ANTI-HIV AGENT

PDB ID 1lp8

Drag the structure with the mouse to rotate

Proteopedia Page Contributors and Editors (what is this?)

OCA

Retrieved from "http://52.214.119.220/wiki/index.php/1lp8"
Personal tools