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1lqo

From Proteopedia

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{{Seed}}
 
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[[Image:1lqo.png|left|200px]]
 
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<!--
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==Crystal Strutcure of the Fosfomycin Resistance Protein A (FosA) Containing Bound Thallium Cations==
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The line below this paragraph, containing "STRUCTURE_1lqo", creates the "Structure Box" on the page.
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<StructureSection load='1lqo' size='340' side='right'caption='[[1lqo]], [[Resolution|resolution]] 2.00&Aring;' scene=''>
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You may change the PDB parameter (which sets the PDB file loaded into the applet)
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== Structural highlights ==
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or the SCENE parameter (which sets the initial scene displayed when the page is loaded),
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<table><tr><td colspan='2'>[[1lqo]] is a 2 chain structure with sequence from [https://en.wikipedia.org/wiki/Pseudomonas_aeruginosa Pseudomonas aeruginosa]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=1LQO OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=1LQO FirstGlance]. <br>
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or leave the SCENE parameter empty for the default display.
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</td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models|Method:]]</b></td><td class="sblockDat" id="methodDat">X-ray diffraction, [[Resolution|Resolution]] 2&#8491;</td></tr>
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<tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=MN:MANGANESE+(II)+ION'>MN</scene>, <scene name='pdbligand=PO4:PHOSPHATE+ION'>PO4</scene>, <scene name='pdbligand=TL:THALLIUM+(I)+ION'>TL</scene></td></tr>
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{{STRUCTURE_1lqo| PDB=1lqo | SCENE= }}
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<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=1lqo FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=1lqo OCA], [https://pdbe.org/1lqo PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=1lqo RCSB], [https://www.ebi.ac.uk/pdbsum/1lqo PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=1lqo ProSAT]</span></td></tr>
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</table>
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===Crystal Strutcure of the Fosfomycin Resistance Protein A (FosA) Containing Bound Thallium Cations===
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== Function ==
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[https://www.uniprot.org/uniprot/FOSA_PSEAE FOSA_PSEAE] Metalloglutathione transferase which confers resistance to fosfomycin by catalyzing the addition of glutathione to fosfomycin.
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== Evolutionary Conservation ==
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[[Image:Consurf_key_small.gif|200px|right]]
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The line below this paragraph, {{ABSTRACT_PUBMED_12224946}}, adds the Publication Abstract to the page
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Check<jmol>
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(as it appears on PubMed at http://www.pubmed.gov), where 12224946 is the PubMed ID number.
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<jmolCheckbox>
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<scriptWhenChecked>; select protein; define ~consurf_to_do selected; consurf_initial_scene = true; script "/wiki/ConSurf/lq/1lqo_consurf.spt"</scriptWhenChecked>
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{{ABSTRACT_PUBMED_12224946}}
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<scriptWhenUnchecked>script /wiki/extensions/Proteopedia/spt/initialview01.spt</scriptWhenUnchecked>
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<text>to colour the structure by Evolutionary Conservation</text>
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==About this Structure==
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</jmolCheckbox>
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1LQO is a [[Single protein]] structure of sequence from [http://en.wikipedia.org/wiki/Pseudomonas_aeruginosa Pseudomonas aeruginosa]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=1LQO OCA].
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</jmol>, as determined by [http://consurfdb.tau.ac.il/ ConSurfDB]. You may read the [[Conservation%2C_Evolutionary|explanation]] of the method and the full data available from [http://bental.tau.ac.il/new_ConSurfDB/main_output.php?pdb_ID=1lqo ConSurf].
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<div style="clear:both"></div>
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==Reference==
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__TOC__
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Crystal structure of a genomically encoded fosfomycin resistance protein (FosA) at 1.19 A resolution by MAD phasing off the L-III edge of Tl(+)., Rife CL, Pharris RE, Newcomer ME, Armstrong RN, J Am Chem Soc. 2002 Sep 18;124(37):11001-3. PMID:[http://www.ncbi.nlm.nih.gov/pubmed/12224946 12224946]
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</StructureSection>
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[[Category: Glutathione transferase]]
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[[Category: Large Structures]]
[[Category: Pseudomonas aeruginosa]]
[[Category: Pseudomonas aeruginosa]]
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[[Category: Single protein]]
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[[Category: Armstrong RN]]
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[[Category: Armstrong, R N.]]
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[[Category: Newcomer ME]]
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[[Category: Newcomer, M E.]]
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[[Category: Pharris RE]]
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[[Category: Pharris, R E.]]
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[[Category: Rife CL]]
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[[Category: Rife, C L.]]
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[[Category: Manganese binding]]
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[[Category: Thallium binding loop]]
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''Page seeded by [http://oca.weizmann.ac.il/oca OCA ] on Wed Jul 2 21:48:45 2008''
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Current revision

Crystal Strutcure of the Fosfomycin Resistance Protein A (FosA) Containing Bound Thallium Cations

PDB ID 1lqo

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