3c7n

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{{Seed}}
 
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[[Image:3c7n.png|left|200px]]
 
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==Structure of the Hsp110:Hsc70 Nucleotide Exchange Complex==
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The line below this paragraph, containing "STRUCTURE_3c7n", creates the "Structure Box" on the page.
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<StructureSection load='3c7n' size='340' side='right'caption='[[3c7n]], [[Resolution|resolution]] 3.12&Aring;' scene=''>
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== Structural highlights ==
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or the SCENE parameter (which sets the initial scene displayed when the page is loaded),
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<table><tr><td colspan='2'>[[3c7n]] is a 2 chain structure with sequence from [https://en.wikipedia.org/wiki/Bos_taurus Bos taurus] and [https://en.wikipedia.org/wiki/Saccharomyces_cerevisiae Saccharomyces cerevisiae]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=3C7N OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=3C7N FirstGlance]. <br>
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</td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models|Method:]]</b></td><td class="sblockDat" id="methodDat">X-ray diffraction, [[Resolution|Resolution]] 3.115&#8491;</td></tr>
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<tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=ADP:ADENOSINE-5-DIPHOSPHATE'>ADP</scene>, <scene name='pdbligand=BEF:BERYLLIUM+TRIFLUORIDE+ION'>BEF</scene>, <scene name='pdbligand=CL:CHLORIDE+ION'>CL</scene>, <scene name='pdbligand=MG:MAGNESIUM+ION'>MG</scene>, <scene name='pdbligand=SO4:SULFATE+ION'>SO4</scene></td></tr>
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{{STRUCTURE_3c7n| PDB=3c7n | SCENE= }}
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<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=3c7n FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=3c7n OCA], [https://pdbe.org/3c7n PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=3c7n RCSB], [https://www.ebi.ac.uk/pdbsum/3c7n PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=3c7n ProSAT]</span></td></tr>
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</table>
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== Function ==
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[https://www.uniprot.org/uniprot/HSP7F_YEAST HSP7F_YEAST] Has a calcium-dependent calmodulin-binding activity. Required for normal growth at various temperatures.
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== Evolutionary Conservation ==
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[[Image:Consurf_key_small.gif|200px|right]]
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Check<jmol>
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<jmolCheckbox>
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<scriptWhenChecked>; select protein; define ~consurf_to_do selected; consurf_initial_scene = true; script "/wiki/ConSurf/c7/3c7n_consurf.spt"</scriptWhenChecked>
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<scriptWhenUnchecked>script /wiki/extensions/Proteopedia/spt/initialview01.spt</scriptWhenUnchecked>
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<text>to colour the structure by Evolutionary Conservation</text>
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</jmolCheckbox>
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</jmol>, as determined by [http://consurfdb.tau.ac.il/ ConSurfDB]. You may read the [[Conservation%2C_Evolutionary|explanation]] of the method and the full data available from [http://bental.tau.ac.il/new_ConSurfDB/main_output.php?pdb_ID=3c7n ConSurf].
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<div style="clear:both"></div>
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===Structure of the Hsp110:Hsc70 Nucleotide Exchange Complex===
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==See Also==
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*[[Heat Shock Protein structures|Heat Shock Protein structures]]
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*[[Heat Shock Proteins|Heat Shock Proteins]]
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</StructureSection>
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(as it appears on PubMed at http://www.pubmed.gov), where 18550409 is the PubMed ID number.
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{{ABSTRACT_PUBMED_18550409}}
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==About this Structure==
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3C7N is a [[Protein complex]] structure of sequences from [http://en.wikipedia.org/wiki/Bos_taurus Bos taurus] and [http://en.wikipedia.org/wiki/Saccharomyces_cerevisiae Saccharomyces cerevisiae]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=3C7N OCA].
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==Reference==
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Structure of the Hsp110:Hsc70 Nucleotide Exchange Machine., Schuermann JP, Jiang J, Cuellar J, Llorca O, Wang L, Gimenez LE, Jin S, Taylor AB, Demeler B, Morano KA, Hart PJ, Valpuesta JM, Lafer EM, Sousa R, Mol Cell. 2008 Jun 10;. PMID:[http://www.ncbi.nlm.nih.gov/pubmed/18550409 18550409]
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[[Category: Bos taurus]]
[[Category: Bos taurus]]
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[[Category: Protein complex]]
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[[Category: Large Structures]]
[[Category: Saccharomyces cerevisiae]]
[[Category: Saccharomyces cerevisiae]]
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[[Category: Hart, P J.]]
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[[Category: Hart PJ]]
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[[Category: Jiang, J.]]
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[[Category: Jiang J]]
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[[Category: Schuermann, J P.]]
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[[Category: Schuermann JP]]
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[[Category: Sousa, R.]]
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[[Category: Sousa R]]
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[[Category: Acetylation]]
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[[Category: Adp]]
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[[Category: Atp state]]
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[[Category: Atp-binding]]
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[[Category: Calmodulin binding]]
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[[Category: Calmodulin-binding]]
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[[Category: Chaperone]]
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[[Category: Chaperone/chaperone complex]]
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[[Category: Cytoplasm]]
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[[Category: Hsc70]]
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[[Category: Hsp110]]
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[[Category: Hsp70]]
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[[Category: Molecular chaperone]]
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[[Category: Mucleotide binding]]
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[[Category: Nucleotide-binding]]
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[[Category: Nucleus]]
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[[Category: Phosphoprotein]]
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[[Category: Phosphorylation]]
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[[Category: Stress response]]
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[[Category: Transcription]]
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''Page seeded by [http://oca.weizmann.ac.il/oca OCA ] on Wed Jul 2 22:05:48 2008''
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Current revision

Structure of the Hsp110:Hsc70 Nucleotide Exchange Complex

PDB ID 3c7n

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OCA

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