1lxm

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{{Seed}}
 
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[[Image:1lxm.png|left|200px]]
 
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==Crystal Structure of Streptococcus agalactiae Hyaluronate Lyase Complexed with Hexasaccharide Unit of Hyaluronan==
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The line below this paragraph, containing "STRUCTURE_1lxm", creates the "Structure Box" on the page.
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<StructureSection load='1lxm' size='340' side='right'caption='[[1lxm]], [[Resolution|resolution]] 2.20&Aring;' scene=''>
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You may change the PDB parameter (which sets the PDB file loaded into the applet)
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== Structural highlights ==
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or the SCENE parameter (which sets the initial scene displayed when the page is loaded),
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<table><tr><td colspan='2'>[[1lxm]] is a 1 chain structure with sequence from [https://en.wikipedia.org/wiki/Streptococcus_agalactiae Streptococcus agalactiae]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=1LXM OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=1LXM FirstGlance]. <br>
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or leave the SCENE parameter empty for the default display.
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</td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models|Method:]]</b></td><td class="sblockDat" id="methodDat">X-ray diffraction, [[Resolution|Resolution]] 2.2&#8491;</td></tr>
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<tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=BDP:BETA-D-GLUCOPYRANURONIC+ACID'>BDP</scene>, <scene name='pdbligand=NAG:N-ACETYL-D-GLUCOSAMINE'>NAG</scene></td></tr>
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{{STRUCTURE_1lxm| PDB=1lxm | SCENE= }}
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<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=1lxm FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=1lxm OCA], [https://pdbe.org/1lxm PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=1lxm RCSB], [https://www.ebi.ac.uk/pdbsum/1lxm PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=1lxm ProSAT]</span></td></tr>
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</table>
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== Function ==
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[https://www.uniprot.org/uniprot/HYSA_STRA3 HYSA_STRA3]
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== Evolutionary Conservation ==
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[[Image:Consurf_key_small.gif|200px|right]]
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Check<jmol>
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<jmolCheckbox>
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<scriptWhenChecked>; select protein; define ~consurf_to_do selected; consurf_initial_scene = true; script "/wiki/ConSurf/lx/1lxm_consurf.spt"</scriptWhenChecked>
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<scriptWhenUnchecked>script /wiki/extensions/Proteopedia/spt/initialview01.spt</scriptWhenUnchecked>
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<text>to colour the structure by Evolutionary Conservation</text>
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</jmolCheckbox>
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</jmol>, as determined by [http://consurfdb.tau.ac.il/ ConSurfDB]. You may read the [[Conservation%2C_Evolutionary|explanation]] of the method and the full data available from [http://bental.tau.ac.il/new_ConSurfDB/main_output.php?pdb_ID=1lxm ConSurf].
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<div style="clear:both"></div>
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===Crystal Structure of Streptococcus agalactiae Hyaluronate Lyase Complexed with Hexasaccharide Unit of Hyaluronan===
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==See Also==
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*[[Hyaluronidase 3D structures|Hyaluronidase 3D structures]]
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__TOC__
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</StructureSection>
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The line below this paragraph, {{ABSTRACT_PUBMED_12130645}}, adds the Publication Abstract to the page
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[[Category: Large Structures]]
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(as it appears on PubMed at http://www.pubmed.gov), where 12130645 is the PubMed ID number.
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{{ABSTRACT_PUBMED_12130645}}
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==About this Structure==
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1LXM is a [[Single protein]] structure of sequence from [http://en.wikipedia.org/wiki/Streptococcus_agalactiae Streptococcus agalactiae]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=1LXM OCA].
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==Reference==
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Structure and flexibility of Streptococcus agalactiae hyaluronate lyase complex with its substrate. Insights into the mechanism of processive degradation of hyaluronan., Mello LV, De Groot BL, Li S, Jedrzejas MJ, J Biol Chem. 2002 Sep 27;277(39):36678-88. Epub 2002 Jul 18. PMID:[http://www.ncbi.nlm.nih.gov/pubmed/12130645 12130645]
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[[Category: Hyaluronate lyase]]
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[[Category: Single protein]]
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[[Category: Streptococcus agalactiae]]
[[Category: Streptococcus agalactiae]]
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[[Category: Groot, B L.de.]]
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[[Category: Jedrzejas MJ]]
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[[Category: Jedrzejas, M J.]]
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[[Category: Li S]]
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[[Category: Li, S.]]
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[[Category: Mello LV]]
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[[Category: Mello, L V.]]
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[[Category: De Groot BL]]
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[[Category: Hyaluronan]]
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[[Category: Protein-carbohydrate complex]]
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[[Category: Streptococcus agalactiae]]
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''Page seeded by [http://oca.weizmann.ac.il/oca OCA ] on Wed Jul 2 22:46:45 2008''
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Current revision

Crystal Structure of Streptococcus agalactiae Hyaluronate Lyase Complexed with Hexasaccharide Unit of Hyaluronan

PDB ID 1lxm

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