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1lyl

From Proteopedia

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{{Seed}}
 
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[[Image:1lyl.png|left|200px]]
 
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==LYSYL-TRNA SYNTHETASE (LYSU) (E.C.6.1.1.6) COMPLEXED WITH LYSINE==
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The line below this paragraph, containing "STRUCTURE_1lyl", creates the "Structure Box" on the page.
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<StructureSection load='1lyl' size='340' side='right'caption='[[1lyl]], [[Resolution|resolution]] 2.80&Aring;' scene=''>
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You may change the PDB parameter (which sets the PDB file loaded into the applet)
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== Structural highlights ==
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or the SCENE parameter (which sets the initial scene displayed when the page is loaded),
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<table><tr><td colspan='2'>[[1lyl]] is a 3 chain structure with sequence from [https://en.wikipedia.org/wiki/Escherichia_coli Escherichia coli]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=1LYL OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=1LYL FirstGlance]. <br>
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or leave the SCENE parameter empty for the default display.
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</td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models|Method:]]</b></td><td class="sblockDat" id="methodDat">X-ray diffraction, [[Resolution|Resolution]] 2.8&#8491;</td></tr>
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<tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=LYS:LYSINE'>LYS</scene></td></tr>
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{{STRUCTURE_1lyl| PDB=1lyl | SCENE= }}
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<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=1lyl FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=1lyl OCA], [https://pdbe.org/1lyl PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=1lyl RCSB], [https://www.ebi.ac.uk/pdbsum/1lyl PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=1lyl ProSAT]</span></td></tr>
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</table>
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== Function ==
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[https://www.uniprot.org/uniprot/SYK2_ECOLI SYK2_ECOLI] Also can synthesize a number of adenyl dinucleotides (in particular AppppA). These dinucleotides have been proposed to act as modulators of the heat-shock response and stress response.[HAMAP-Rule:MF_00252]
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== Evolutionary Conservation ==
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[[Image:Consurf_key_small.gif|200px|right]]
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Check<jmol>
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<jmolCheckbox>
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<scriptWhenChecked>; select protein; define ~consurf_to_do selected; consurf_initial_scene = true; script "/wiki/ConSurf/ly/1lyl_consurf.spt"</scriptWhenChecked>
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<scriptWhenUnchecked>script /wiki/extensions/Proteopedia/spt/initialview01.spt</scriptWhenUnchecked>
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<text>to colour the structure by Evolutionary Conservation</text>
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</jmolCheckbox>
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</jmol>, as determined by [http://consurfdb.tau.ac.il/ ConSurfDB]. You may read the [[Conservation%2C_Evolutionary|explanation]] of the method and the full data available from [http://bental.tau.ac.il/new_ConSurfDB/main_output.php?pdb_ID=1lyl ConSurf].
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<div style="clear:both"></div>
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===LYSYL-TRNA SYNTHETASE (LYSU) (E.C.6.1.1.6) COMPLEXED WITH LYSINE===
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==See Also==
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*[[Aminoacyl tRNA synthetase 3D structures|Aminoacyl tRNA synthetase 3D structures]]
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__TOC__
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</StructureSection>
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The line below this paragraph, {{ABSTRACT_PUBMED_7735833}}, adds the Publication Abstract to the page
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(as it appears on PubMed at http://www.pubmed.gov), where 7735833 is the PubMed ID number.
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{{ABSTRACT_PUBMED_7735833}}
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==About this Structure==
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1LYL is a [[Single protein]] structure of sequence from [http://en.wikipedia.org/wiki/Escherichia_coli Escherichia coli]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=1LYL OCA].
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==Reference==
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The crystal structure of the lysyl-tRNA synthetase (LysU) from Escherichia coli., Onesti S, Miller AD, Brick P, Structure. 1995 Feb 15;3(2):163-76. PMID:[http://www.ncbi.nlm.nih.gov/pubmed/7735833 7735833]
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[[Category: Escherichia coli]]
[[Category: Escherichia coli]]
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[[Category: Lysine--tRNA ligase]]
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[[Category: Large Structures]]
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[[Category: Single protein]]
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[[Category: Brick P]]
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[[Category: Brick, P.]]
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[[Category: Onesti S]]
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[[Category: Onesti, S.]]
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''Page seeded by [http://oca.weizmann.ac.il/oca OCA ] on Wed Jul 2 22:49:51 2008''
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Current revision

LYSYL-TRNA SYNTHETASE (LYSU) (E.C.6.1.1.6) COMPLEXED WITH LYSINE

PDB ID 1lyl

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