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1m0p

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{{Seed}}
 
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[[Image:1m0p.png|left|200px]]
 
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<!--
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==Structure of Dialkylglycine Decarboxylase Complexed with 1-Amino-1-phenylethanephosphonate==
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The line below this paragraph, containing "STRUCTURE_1m0p", creates the "Structure Box" on the page.
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<StructureSection load='1m0p' size='340' side='right'caption='[[1m0p]], [[Resolution|resolution]] 2.60&Aring;' scene=''>
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You may change the PDB parameter (which sets the PDB file loaded into the applet)
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== Structural highlights ==
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or the SCENE parameter (which sets the initial scene displayed when the page is loaded),
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<table><tr><td colspan='2'>[[1m0p]] is a 1 chain structure with sequence from [https://en.wikipedia.org/wiki/Burkholderia_cepacia Burkholderia cepacia]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=1M0P OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=1M0P FirstGlance]. <br>
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or leave the SCENE parameter empty for the default display.
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</td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models|Method:]]</b></td><td class="sblockDat" id="methodDat">X-ray diffraction, [[Resolution|Resolution]] 2.6&#8491;</td></tr>
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<tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=ELP:(1R)-1-[((1E)-{3-HYDROXY-2-METHYL-5-[(PHOSPHONOOXY)METHYL]PYRIDIN-4-YL}METHYLENE)AMINO]-1-PHENYLETHYLPHOSPHONIC+ACID'>ELP</scene>, <scene name='pdbligand=K:POTASSIUM+ION'>K</scene>, <scene name='pdbligand=NA:SODIUM+ION'>NA</scene></td></tr>
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{{STRUCTURE_1m0p| PDB=1m0p | SCENE= }}
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<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=1m0p FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=1m0p OCA], [https://pdbe.org/1m0p PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=1m0p RCSB], [https://www.ebi.ac.uk/pdbsum/1m0p PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=1m0p ProSAT]</span></td></tr>
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</table>
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===Structure of Dialkylglycine Decarboxylase Complexed with 1-Amino-1-phenylethanephosphonate===
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== Function ==
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[https://www.uniprot.org/uniprot/DGDA_BURCE DGDA_BURCE] The dialkylglycine decarboxylase is of interest because it normally catalyzes both decarboxylation and amino transfer. It may be more properly described as a decarboxylating aminotransferase rather than an aminotransferring decarboxylase.
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== Evolutionary Conservation ==
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[[Image:Consurf_key_small.gif|200px|right]]
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The line below this paragraph, {{ABSTRACT_PUBMED_12369820}}, adds the Publication Abstract to the page
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Check<jmol>
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(as it appears on PubMed at http://www.pubmed.gov), where 12369820 is the PubMed ID number.
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<jmolCheckbox>
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<scriptWhenChecked>; select protein; define ~consurf_to_do selected; consurf_initial_scene = true; script "/wiki/ConSurf/m0/1m0p_consurf.spt"</scriptWhenChecked>
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{{ABSTRACT_PUBMED_12369820}}
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<scriptWhenUnchecked>script /wiki/extensions/Proteopedia/spt/initialview01.spt</scriptWhenUnchecked>
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<text>to colour the structure by Evolutionary Conservation</text>
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==About this Structure==
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</jmolCheckbox>
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1M0P is a [[Single protein]] structure of sequence from [http://en.wikipedia.org/wiki/Burkholderia_cepacia Burkholderia cepacia]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=1M0P OCA].
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</jmol>, as determined by [http://consurfdb.tau.ac.il/ ConSurfDB]. You may read the [[Conservation%2C_Evolutionary|explanation]] of the method and the full data available from [http://bental.tau.ac.il/new_ConSurfDB/main_output.php?pdb_ID=1m0p ConSurf].
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<div style="clear:both"></div>
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==Reference==
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__TOC__
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Aminophosphonate inhibitors of dialkylglycine decarboxylase: structural basis for slow binding inhibition., Liu W, Rogers CJ, Fisher AJ, Toney MD, Biochemistry. 2002 Oct 15;41(41):12320-8. PMID:[http://www.ncbi.nlm.nih.gov/pubmed/12369820 12369820]
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</StructureSection>
[[Category: Burkholderia cepacia]]
[[Category: Burkholderia cepacia]]
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[[Category: Single protein]]
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[[Category: Large Structures]]
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[[Category: Fisher, A J.]]
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[[Category: Fisher AJ]]
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[[Category: Liu, W.]]
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[[Category: Liu W]]
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[[Category: Rogers, C J.]]
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[[Category: Rogers CJ]]
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[[Category: Toney, M D.]]
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[[Category: Toney MD]]
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[[Category: 3d-structure]]
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[[Category: Decarboxylase]]
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[[Category: Pyridoxal phosphate]]
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''Page seeded by [http://oca.weizmann.ac.il/oca OCA ] on Wed Jul 2 22:57:40 2008''
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Current revision

Structure of Dialkylglycine Decarboxylase Complexed with 1-Amino-1-phenylethanephosphonate

PDB ID 1m0p

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