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1m0u

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{{Seed}}
 
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[[Image:1m0u.png|left|200px]]
 
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==Crystal Structure of the Drosophila Glutathione S-transferase-2 in Complex with Glutathione==
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The line below this paragraph, containing "STRUCTURE_1m0u", creates the "Structure Box" on the page.
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<StructureSection load='1m0u' size='340' side='right'caption='[[1m0u]], [[Resolution|resolution]] 1.75&Aring;' scene=''>
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You may change the PDB parameter (which sets the PDB file loaded into the applet)
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== Structural highlights ==
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or the SCENE parameter (which sets the initial scene displayed when the page is loaded),
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<table><tr><td colspan='2'>[[1m0u]] is a 2 chain structure with sequence from [https://en.wikipedia.org/wiki/Drosophila_melanogaster Drosophila melanogaster]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=1M0U OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=1M0U FirstGlance]. <br>
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or leave the SCENE parameter empty for the default display.
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</td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models|Method:]]</b></td><td class="sblockDat" id="methodDat">X-ray diffraction, [[Resolution|Resolution]] 1.75&#8491;</td></tr>
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<tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=GSH:GLUTATHIONE'>GSH</scene>, <scene name='pdbligand=SO4:SULFATE+ION'>SO4</scene></td></tr>
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{{STRUCTURE_1m0u| PDB=1m0u | SCENE= }}
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<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=1m0u FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=1m0u OCA], [https://pdbe.org/1m0u PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=1m0u RCSB], [https://www.ebi.ac.uk/pdbsum/1m0u PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=1m0u ProSAT]</span></td></tr>
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</table>
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== Function ==
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[https://www.uniprot.org/uniprot/GSTS1_DROME GSTS1_DROME] Conjugation of reduced glutathione to a wide number of exogenous and endogenous hydrophobic electrophiles (PubMed:22082028). May be involved in the detoxification of metabolites produced during cellular division and morphogenesis (PubMed:1445191, PubMed:12547198).<ref>PMID:12547198</ref> <ref>PMID:1445191</ref> <ref>PMID:22082028</ref>
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== Evolutionary Conservation ==
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[[Image:Consurf_key_small.gif|200px|right]]
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Check<jmol>
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<jmolCheckbox>
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<scriptWhenChecked>; select protein; define ~consurf_to_do selected; consurf_initial_scene = true; script "/wiki/ConSurf/m0/1m0u_consurf.spt"</scriptWhenChecked>
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<scriptWhenUnchecked>script /wiki/extensions/Proteopedia/spt/initialview01.spt</scriptWhenUnchecked>
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<text>to colour the structure by Evolutionary Conservation</text>
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</jmolCheckbox>
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</jmol>, as determined by [http://consurfdb.tau.ac.il/ ConSurfDB]. You may read the [[Conservation%2C_Evolutionary|explanation]] of the method and the full data available from [http://bental.tau.ac.il/new_ConSurfDB/main_output.php?pdb_ID=1m0u ConSurf].
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<div style="clear:both"></div>
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===Crystal Structure of the Drosophila Glutathione S-transferase-2 in Complex with Glutathione===
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==See Also==
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*[[Glutathione S-transferase 3D structures|Glutathione S-transferase 3D structures]]
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== References ==
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<references/>
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The line below this paragraph, {{ABSTRACT_PUBMED_12547198}}, adds the Publication Abstract to the page
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__TOC__
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(as it appears on PubMed at http://www.pubmed.gov), where 12547198 is the PubMed ID number.
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</StructureSection>
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{{ABSTRACT_PUBMED_12547198}}
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==About this Structure==
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1M0U is a [[Single protein]] structure of sequence from [http://en.wikipedia.org/wiki/Drosophila_melanogaster Drosophila melanogaster]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=1M0U OCA].
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==Reference==
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Structure of a Drosophila sigma class glutathione S-transferase reveals a novel active site topography suited for lipid peroxidation products., Agianian B, Tucker PA, Schouten A, Leonard K, Bullard B, Gros P, J Mol Biol. 2003 Feb 7;326(1):151-65. PMID:[http://www.ncbi.nlm.nih.gov/pubmed/12547198 12547198]
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[[Category: Drosophila melanogaster]]
[[Category: Drosophila melanogaster]]
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[[Category: Glutathione transferase]]
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[[Category: Large Structures]]
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[[Category: Single protein]]
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[[Category: Agianian B]]
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[[Category: Agianian, B.]]
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[[Category: Bullard B]]
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[[Category: Bullard, B.]]
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[[Category: Gros P]]
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[[Category: Gros, P.]]
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[[Category: Leonard K]]
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[[Category: Leonard, K.]]
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[[Category: Schouten A]]
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[[Category: Schouten, A.]]
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[[Category: Tucker PA]]
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[[Category: Tucker, P A.]]
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[[Category: Flight muscle protein]]
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[[Category: Gst]]
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[[Category: Sigma]]
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''Page seeded by [http://oca.weizmann.ac.il/oca OCA ] on Wed Jul 2 22:58:08 2008''
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Current revision

Crystal Structure of the Drosophila Glutathione S-transferase-2 in Complex with Glutathione

PDB ID 1m0u

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