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1m26

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{{Seed}}
 
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[[Image:1m26.png|left|200px]]
 
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==Crystal structure of jacalin-T-antigen complex==
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The line below this paragraph, containing "STRUCTURE_1m26", creates the "Structure Box" on the page.
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<StructureSection load='1m26' size='340' side='right'caption='[[1m26]], [[Resolution|resolution]] 1.62&Aring;' scene=''>
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You may change the PDB parameter (which sets the PDB file loaded into the applet)
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== Structural highlights ==
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or the SCENE parameter (which sets the initial scene displayed when the page is loaded),
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<table><tr><td colspan='2'>[[1m26]] is a 8 chain structure with sequence from [https://en.wikipedia.org/wiki/Artocarpus_integer Artocarpus integer]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=1M26 OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=1M26 FirstGlance]. <br>
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or leave the SCENE parameter empty for the default display.
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</td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models|Method:]]</b></td><td class="sblockDat" id="methodDat">X-ray diffraction, [[Resolution|Resolution]] 1.62&#8491;</td></tr>
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<tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=A2G:N-ACETYL-2-DEOXY-2-AMINO-GALACTOSE'>A2G</scene>, <scene name='pdbligand=GAL:BETA-D-GALACTOSE'>GAL</scene>, <scene name='pdbligand=PRD_900084:Thomsen-Friedenreich+antigen'>PRD_900084</scene></td></tr>
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{{STRUCTURE_1m26| PDB=1m26 | SCENE= }}
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<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=1m26 FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=1m26 OCA], [https://pdbe.org/1m26 PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=1m26 RCSB], [https://www.ebi.ac.uk/pdbsum/1m26 PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=1m26 ProSAT]</span></td></tr>
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</table>
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== Function ==
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[https://www.uniprot.org/uniprot/LECA_ARTIN LECA_ARTIN] D-galactose-specific lectin, binds the T-antigen structure Gal-beta1,3-GalNAc (Thomsen-Friedenreich-antigen-specific lectin). Potent and selective stimulant of distinct T- and B-cell functions. Shows a unique ability to specifically recognize IgA-1 from human serum.
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== Evolutionary Conservation ==
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[[Image:Consurf_key_small.gif|200px|right]]
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Check<jmol>
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<jmolCheckbox>
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<scriptWhenChecked>; select protein; define ~consurf_to_do selected; consurf_initial_scene = true; script "/wiki/ConSurf/m2/1m26_consurf.spt"</scriptWhenChecked>
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<scriptWhenUnchecked>script /wiki/extensions/Proteopedia/spt/initialview01.spt</scriptWhenUnchecked>
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<text>to colour the structure by Evolutionary Conservation</text>
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</jmolCheckbox>
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</jmol>, as determined by [http://consurfdb.tau.ac.il/ ConSurfDB]. You may read the [[Conservation%2C_Evolutionary|explanation]] of the method and the full data available from [http://bental.tau.ac.il/new_ConSurfDB/main_output.php?pdb_ID=1m26 ConSurf].
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<div style="clear:both"></div>
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===Crystal structure of jacalin-T-antigen complex===
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==See Also==
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*[[Agglutinin 3D structures|Agglutinin 3D structures]]
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__TOC__
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</StructureSection>
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The line below this paragraph, {{ABSTRACT_PUBMED_12206779}}, adds the Publication Abstract to the page
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[[Category: Artocarpus integer]]
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(as it appears on PubMed at http://www.pubmed.gov), where 12206779 is the PubMed ID number.
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[[Category: Large Structures]]
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[[Category: Banumathi S]]
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{{ABSTRACT_PUBMED_12206779}}
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[[Category: Betzel C]]
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[[Category: Jeyaprakash AA]]
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==About this Structure==
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[[Category: Rani PG]]
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1M26 is a [[Protein complex]] structure of sequences from [http://en.wikipedia.org/wiki/Artocarpus_integrifolia Artocarpus integrifolia]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=1M26 OCA].
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[[Category: Reddy GB]]
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[[Category: Surolia A]]
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==Reference==
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[[Category: Vijayan M]]
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Crystal structure of the jacalin-T-antigen complex and a comparative study of lectin-T-antigen complexes., Jeyaprakash AA, Geetha Rani P, Banuprakash Reddy G, Banumathi S, Betzel C, Sekar K, Surolia A, Vijayan M, J Mol Biol. 2002 Aug 23;321(4):637-45. PMID:[http://www.ncbi.nlm.nih.gov/pubmed/12206779 12206779]
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[[Category: Artocarpus integrifolia]]
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[[Category: Protein complex]]
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[[Category: Banumathi, S.]]
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[[Category: Betzel, C.]]
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[[Category: Jeyaprakash, A A.]]
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[[Category: Rani, P G.]]
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[[Category: Reddy, G B.]]
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[[Category: Surolia, A.]]
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[[Category: Vijayan, M.]]
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[[Category: All beta sheet protein]]
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[[Category: Beta prism i fold]]
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''Page seeded by [http://oca.weizmann.ac.il/oca OCA ] on Wed Jul 2 23:03:39 2008''
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Current revision

Crystal structure of jacalin-T-antigen complex

PDB ID 1m26

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