1m3u

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{{Seed}}
 
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[[Image:1m3u.png|left|200px]]
 
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==Crystal Structure of Ketopantoate Hydroxymethyltransferase complexed the Product Ketopantoate==
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The line below this paragraph, containing "STRUCTURE_1m3u", creates the "Structure Box" on the page.
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<StructureSection load='1m3u' size='340' side='right'caption='[[1m3u]], [[Resolution|resolution]] 1.80&Aring;' scene=''>
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You may change the PDB parameter (which sets the PDB file loaded into the applet)
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== Structural highlights ==
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or the SCENE parameter (which sets the initial scene displayed when the page is loaded),
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<table><tr><td colspan='2'>[[1m3u]] is a 10 chain structure with sequence from [https://en.wikipedia.org/wiki/Escherichia_coli Escherichia coli]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=1M3U OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=1M3U FirstGlance]. <br>
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or leave the SCENE parameter empty for the default display.
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</td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models|Method:]]</b></td><td class="sblockDat" id="methodDat">X-ray diffraction, [[Resolution|Resolution]] 1.8&#8491;</td></tr>
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<tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=KPL:KETOPANTOATE'>KPL</scene>, <scene name='pdbligand=MG:MAGNESIUM+ION'>MG</scene></td></tr>
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{{STRUCTURE_1m3u| PDB=1m3u | SCENE= }}
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<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=1m3u FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=1m3u OCA], [https://pdbe.org/1m3u PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=1m3u RCSB], [https://www.ebi.ac.uk/pdbsum/1m3u PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=1m3u ProSAT]</span></td></tr>
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</table>
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===Crystal Structure of Ketopantoate Hydroxymethyltransferase complexed the Product Ketopantoate===
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== Function ==
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[https://www.uniprot.org/uniprot/PANB_ECOLI PANB_ECOLI] Catalyzes the reversible reaction in which hydroxymethyl group from 5,10-methylenetetrahydrofolate is tranferred onto alpha-ketoisovalerate to form ketopantoate.<ref>PMID:776976</ref>
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== Evolutionary Conservation ==
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[[Image:Consurf_key_small.gif|200px|right]]
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Check<jmol>
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(as it appears on PubMed at http://www.pubmed.gov), where 12906829 is the PubMed ID number.
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<jmolCheckbox>
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<scriptWhenChecked>; select protein; define ~consurf_to_do selected; consurf_initial_scene = true; script "/wiki/ConSurf/m3/1m3u_consurf.spt"</scriptWhenChecked>
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{{ABSTRACT_PUBMED_12906829}}
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<scriptWhenUnchecked>script /wiki/extensions/Proteopedia/spt/initialview01.spt</scriptWhenUnchecked>
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<text>to colour the structure by Evolutionary Conservation</text>
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==About this Structure==
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</jmolCheckbox>
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1M3U is a [[Single protein]] structure of sequence from [http://en.wikipedia.org/wiki/Escherichia_coli Escherichia coli]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=1M3U OCA].
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</jmol>, as determined by [http://consurfdb.tau.ac.il/ ConSurfDB]. You may read the [[Conservation%2C_Evolutionary|explanation]] of the method and the full data available from [http://bental.tau.ac.il/new_ConSurfDB/main_output.php?pdb_ID=1m3u ConSurf].
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<div style="clear:both"></div>
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==Reference==
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== References ==
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Structure of E. coli ketopantoate hydroxymethyl transferase complexed with ketopantoate and Mg2+, solved by locating 160 selenomethionine sites., von Delft F, Inoue T, Saldanha SA, Ottenhof HH, Schmitzberger F, Birch LM, Dhanaraj V, Witty M, Smith AG, Blundell TL, Abell C, Structure. 2003 Aug;11(8):985-96. PMID:[http://www.ncbi.nlm.nih.gov/pubmed/12906829 12906829]
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<references/>
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[[Category: 3-methyl-2-oxobutanoate hydroxymethyltransferase]]
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__TOC__
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</StructureSection>
[[Category: Escherichia coli]]
[[Category: Escherichia coli]]
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[[Category: Single protein]]
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[[Category: Large Structures]]
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[[Category: Abell, C.]]
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[[Category: Abell C]]
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[[Category: Blundell, T L.]]
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[[Category: Blundell TL]]
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[[Category: Delft, F von.]]
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[[Category: Dhanaraj V]]
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[[Category: Dhanaraj, V.]]
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[[Category: Inoue T]]
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[[Category: Inoue, T.]]
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[[Category: Ottenhof HH]]
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[[Category: Ottenhof, H H.]]
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[[Category: Saldanha SA]]
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[[Category: Saldanha, S A.]]
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[[Category: Smith AG]]
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[[Category: Smith, A G.]]
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[[Category: Witty M]]
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[[Category: Witty, M.]]
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[[Category: Von Delft F]]
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[[Category: Beta-alpha-barrel]]
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[[Category: Decamer]]
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[[Category: Ketopantoate]]
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[[Category: Selenomethionine mad]]
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[[Category: Tim-barrel]]
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''Page seeded by [http://oca.weizmann.ac.il/oca OCA ] on Wed Jul 2 23:08:46 2008''
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Current revision

Crystal Structure of Ketopantoate Hydroxymethyltransferase complexed the Product Ketopantoate

PDB ID 1m3u

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