1m4r

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{{Seed}}
 
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[[Image:1m4r.png|left|200px]]
 
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==CRYSTAL STRUCTURE OF RECOMBINANT HUMAN INTERLEUKIN-22==
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The line below this paragraph, containing "STRUCTURE_1m4r", creates the "Structure Box" on the page.
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<StructureSection load='1m4r' size='340' side='right'caption='[[1m4r]], [[Resolution|resolution]] 2.00&Aring;' scene=''>
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You may change the PDB parameter (which sets the PDB file loaded into the applet)
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== Structural highlights ==
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or the SCENE parameter (which sets the initial scene displayed when the page is loaded),
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<table><tr><td colspan='2'>[[1m4r]] is a 2 chain structure with sequence from [https://en.wikipedia.org/wiki/Homo_sapiens Homo sapiens]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=1M4R OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=1M4R FirstGlance]. <br>
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or leave the SCENE parameter empty for the default display.
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</td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models|Method:]]</b></td><td class="sblockDat" id="methodDat">X-ray diffraction, [[Resolution|Resolution]] 2&#8491;</td></tr>
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<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=1m4r FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=1m4r OCA], [https://pdbe.org/1m4r PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=1m4r RCSB], [https://www.ebi.ac.uk/pdbsum/1m4r PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=1m4r ProSAT]</span></td></tr>
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{{STRUCTURE_1m4r| PDB=1m4r | SCENE= }}
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</table>
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== Function ==
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[https://www.uniprot.org/uniprot/IL22_HUMAN IL22_HUMAN] Cytokine that contributes to the inflammatory response in vivo.
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== Evolutionary Conservation ==
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[[Image:Consurf_key_small.gif|200px|right]]
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Check<jmol>
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<jmolCheckbox>
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<scriptWhenChecked>; select protein; define ~consurf_to_do selected; consurf_initial_scene = true; script "/wiki/ConSurf/m4/1m4r_consurf.spt"</scriptWhenChecked>
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<scriptWhenUnchecked>script /wiki/extensions/Proteopedia/spt/initialview01.spt</scriptWhenUnchecked>
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<text>to colour the structure by Evolutionary Conservation</text>
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</jmolCheckbox>
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</jmol>, as determined by [http://consurfdb.tau.ac.il/ ConSurfDB]. You may read the [[Conservation%2C_Evolutionary|explanation]] of the method and the full data available from [http://bental.tau.ac.il/new_ConSurfDB/main_output.php?pdb_ID=1m4r ConSurf].
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<div style="clear:both"></div>
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===CRYSTAL STRUCTURE OF RECOMBINANT HUMAN INTERLEUKIN-22===
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==See Also==
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*[[Interleukin 3D structures|Interleukin 3D structures]]
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__TOC__
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</StructureSection>
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The line below this paragraph, {{ABSTRACT_PUBMED_12176383}}, adds the Publication Abstract to the page
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(as it appears on PubMed at http://www.pubmed.gov), where 12176383 is the PubMed ID number.
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{{ABSTRACT_PUBMED_12176383}}
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==About this Structure==
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1M4R is a [[Single protein]] structure of sequence from [http://en.wikipedia.org/wiki/Homo_sapiens Homo sapiens]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=1M4R OCA].
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==Reference==
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Crystal structure of recombinant human interleukin-22., Nagem RA, Colau D, Dumoutier L, Renauld JC, Ogata C, Polikarpov I, Structure. 2002 Aug;10(8):1051-62. PMID:[http://www.ncbi.nlm.nih.gov/pubmed/12176383 12176383]
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[[Category: Homo sapiens]]
[[Category: Homo sapiens]]
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[[Category: Single protein]]
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[[Category: Large Structures]]
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[[Category: Colau, D.]]
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[[Category: Colau D]]
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[[Category: Dumoutier, L.]]
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[[Category: Dumoutier L]]
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[[Category: Nagem, R A.P.]]
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[[Category: Nagem RAP]]
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[[Category: Ogata, C.]]
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[[Category: Ogata C]]
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[[Category: Polikarpov, I.]]
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[[Category: Polikarpov I]]
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[[Category: Renauld, J C.]]
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[[Category: Renauld J-C]]
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[[Category: Crystal structure]]
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[[Category: Cytokine]]
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[[Category: Interferon-gamma]]
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''Page seeded by [http://oca.weizmann.ac.il/oca OCA ] on Wed Jul 2 23:12:21 2008''
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Current revision

CRYSTAL STRUCTURE OF RECOMBINANT HUMAN INTERLEUKIN-22

PDB ID 1m4r

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