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1m9e

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{{Seed}}
 
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[[Image:1m9e.png|left|200px]]
 
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==X-ray crystal structure of Cyclophilin A/HIV-1 CA N-terminal domain (1-146) M-type H87A Complex.==
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The line below this paragraph, containing "STRUCTURE_1m9e", creates the "Structure Box" on the page.
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<StructureSection load='1m9e' size='340' side='right'caption='[[1m9e]], [[Resolution|resolution]] 1.72&Aring;' scene=''>
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You may change the PDB parameter (which sets the PDB file loaded into the applet)
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== Structural highlights ==
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or the SCENE parameter (which sets the initial scene displayed when the page is loaded),
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<table><tr><td colspan='2'>[[1m9e]] is a 4 chain structure with sequence from [https://en.wikipedia.org/wiki/Homo_sapiens Homo sapiens] and [https://en.wikipedia.org/wiki/Human_immunodeficiency_virus_1 Human immunodeficiency virus 1]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=1M9E OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=1M9E FirstGlance]. <br>
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</td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models|Method:]]</b></td><td class="sblockDat" id="methodDat">X-ray diffraction, [[Resolution|Resolution]] 1.72&#8491;</td></tr>
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<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=1m9e FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=1m9e OCA], [https://pdbe.org/1m9e PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=1m9e RCSB], [https://www.ebi.ac.uk/pdbsum/1m9e PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=1m9e ProSAT]</span></td></tr>
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{{STRUCTURE_1m9e| PDB=1m9e | SCENE= }}
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</table>
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== Function ==
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[https://www.uniprot.org/uniprot/PPIA_HUMAN PPIA_HUMAN] PPIases accelerate the folding of proteins. It catalyzes the cis-trans isomerization of proline imidic peptide bonds in oligopeptides.
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== Evolutionary Conservation ==
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[[Image:Consurf_key_small.gif|200px|right]]
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Check<jmol>
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<jmolCheckbox>
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<scriptWhenChecked>; select protein; define ~consurf_to_do selected; consurf_initial_scene = true; script "/wiki/ConSurf/m9/1m9e_consurf.spt"</scriptWhenChecked>
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<scriptWhenUnchecked>script /wiki/extensions/Proteopedia/spt/initialview01.spt</scriptWhenUnchecked>
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<text>to colour the structure by Evolutionary Conservation</text>
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</jmolCheckbox>
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</jmol>, as determined by [http://consurfdb.tau.ac.il/ ConSurfDB]. You may read the [[Conservation%2C_Evolutionary|explanation]] of the method and the full data available from [http://bental.tau.ac.il/new_ConSurfDB/main_output.php?pdb_ID=1m9e ConSurf].
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<div style="clear:both"></div>
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===X-ray crystal structure of Cyclophilin A/HIV-1 CA N-terminal domain (1-146) M-type H87A Complex.===
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==See Also==
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*[[Cyclophilin 3D structures|Cyclophilin 3D structures]]
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*[[Virus coat proteins 3D structures|Virus coat proteins 3D structures]]
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__TOC__
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The line below this paragraph, {{ABSTRACT_PUBMED_12730686}}, adds the Publication Abstract to the page
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</StructureSection>
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(as it appears on PubMed at http://www.pubmed.gov), where 12730686 is the PubMed ID number.
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{{ABSTRACT_PUBMED_12730686}}
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==About this Structure==
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1M9E is a [[Protein complex]] structure of sequences from [http://en.wikipedia.org/wiki/Homo_sapiens Homo sapiens] and [http://en.wikipedia.org/wiki/Human_immunodeficiency_virus_1 Human immunodeficiency virus 1]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=1M9E OCA].
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==Reference==
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Structural insights into the catalytic mechanism of cyclophilin A., Howard BR, Vajdos FF, Li S, Sundquist WI, Hill CP, Nat Struct Biol. 2003 Jun;10(6):475-81. PMID:[http://www.ncbi.nlm.nih.gov/pubmed/12730686 12730686]
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[[Category: Homo sapiens]]
[[Category: Homo sapiens]]
[[Category: Human immunodeficiency virus 1]]
[[Category: Human immunodeficiency virus 1]]
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[[Category: Peptidylprolyl isomerase]]
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[[Category: Large Structures]]
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[[Category: Protein complex]]
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[[Category: Hill CP]]
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[[Category: Hill, C P.]]
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[[Category: Howard BR]]
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[[Category: Howard, B R.]]
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[[Category: Li S]]
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[[Category: Li, S.]]
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[[Category: Sundquist WI]]
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[[Category: Sundquist, W I.]]
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[[Category: Vajdos FF]]
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[[Category: Vajdos, F F.]]
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[[Category: Capsid]]
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[[Category: Cyclophilin some]]
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[[Category: Hiv-1]]
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[[Category: Isomerase]]
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[[Category: Rotamase]]
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''Page seeded by [http://oca.weizmann.ac.il/oca OCA ] on Wed Jul 2 23:29:07 2008''
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Current revision

X-ray crystal structure of Cyclophilin A/HIV-1 CA N-terminal domain (1-146) M-type H87A Complex.

PDB ID 1m9e

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