1md2

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{{Seed}}
 
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[[Image:1md2.png|left|200px]]
 
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==CHOLERA TOXIN B-PENTAMER WITH DECAVALENT LIGAND BMSC-0013==
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The line below this paragraph, containing "STRUCTURE_1md2", creates the "Structure Box" on the page.
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<StructureSection load='1md2' size='340' side='right'caption='[[1md2]], [[Resolution|resolution]] 1.45&Aring;' scene=''>
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== Structural highlights ==
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or the SCENE parameter (which sets the initial scene displayed when the page is loaded),
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<table><tr><td colspan='2'>[[1md2]] is a 5 chain structure with sequence from [https://en.wikipedia.org/wiki/Vibrio_cholerae Vibrio cholerae]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=1MD2 OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=1MD2 FirstGlance]. <br>
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</td></tr><tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=233:[5-(3,4,5-TRIHYDROXY-6-HYDROXYMETHYL-TETRAHYDRO-PYRAN-2-YLCARBAMOYL)-PENTYL]-CARBAMIC+ACID+METHYL+ESTER'>233</scene>, <scene name='pdbligand=CSS:S-MERCAPTOCYSTEINE'>CSS</scene>, <scene name='pdbligand=CYN:CYANIDE+ION'>CYN</scene>, <scene name='pdbligand=SQ:3-ETHYLAMINO-4-METHYLAMINO-CYCLOBUTANE-1,2-DIONE'>SQ</scene></td></tr>
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<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=1md2 FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=1md2 OCA], [https://pdbe.org/1md2 PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=1md2 RCSB], [https://www.ebi.ac.uk/pdbsum/1md2 PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=1md2 ProSAT]</span></td></tr>
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{{STRUCTURE_1md2| PDB=1md2 | SCENE= }}
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</table>
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== Function ==
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[[https://www.uniprot.org/uniprot/CHTB_VIBCH CHTB_VIBCH]] The B subunit pentameric ring directs the A subunit to its target by binding to the GM1 gangliosides present on the surface of the intestinal epithelial cells. It can bind five GM1 gangliosides. It has no toxic activity by itself.
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===CHOLERA TOXIN B-PENTAMER WITH DECAVALENT LIGAND BMSC-0013===
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==See Also==
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*[[Cholera toxin 3D structures|Cholera toxin 3D structures]]
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*[[User:David Solfiell/sandbox 1|User:David Solfiell/sandbox 1]]
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__TOC__
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</StructureSection>
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(as it appears on PubMed at http://www.pubmed.gov), where 12405825 is the PubMed ID number.
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[[Category: Large Structures]]
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{{ABSTRACT_PUBMED_12405825}}
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==About this Structure==
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1MD2 is a [[Single protein]] structure of sequence from [http://en.wikipedia.org/wiki/Vibrio_cholerae Vibrio cholerae]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=1MD2 OCA].
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==Reference==
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Solution and crystallographic studies of branched multivalent ligands that inhibit the receptor-binding of cholera toxin., Zhang Z, Merritt EA, Ahn M, Roach C, Hou Z, Verlinde CL, Hol WG, Fan E, J Am Chem Soc. 2002 Nov 6;124(44):12991-8. PMID:[http://www.ncbi.nlm.nih.gov/pubmed/12405825 12405825]
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[[Category: Single protein]]
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[[Category: Vibrio cholerae]]
[[Category: Vibrio cholerae]]
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[[Category: Ahn, M.]]
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[[Category: Ahn M]]
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[[Category: Fan, E.]]
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[[Category: Fan E]]
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[[Category: Hol, W G.J.]]
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[[Category: Hol WGJ]]
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[[Category: Merritt, E A.]]
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[[Category: Merritt EA]]
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[[Category: Roach, C.]]
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[[Category: Roach C]]
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[[Category: Zhang, Z.]]
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[[Category: Zhang Z]]
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[[Category: Multivalent inhibitor toxin]]
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''Page seeded by [http://oca.weizmann.ac.il/oca OCA ] on Wed Jul 2 23:42:32 2008''
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Current revision

CHOLERA TOXIN B-PENTAMER WITH DECAVALENT LIGAND BMSC-0013

PDB ID 1md2

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