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1mij

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{{Seed}}
 
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[[Image:1mij.png|left|200px]]
 
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==Crystal Structure of the Homeo-prospero Domain of D. melanogaster Prospero==
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The line below this paragraph, containing "STRUCTURE_1mij", creates the "Structure Box" on the page.
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<StructureSection load='1mij' size='340' side='right'caption='[[1mij]], [[Resolution|resolution]] 2.05&Aring;' scene=''>
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You may change the PDB parameter (which sets the PDB file loaded into the applet)
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== Structural highlights ==
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or the SCENE parameter (which sets the initial scene displayed when the page is loaded),
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<table><tr><td colspan='2'>[[1mij]] is a 1 chain structure with sequence from [https://en.wikipedia.org/wiki/Drosophila_melanogaster Drosophila melanogaster]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=1MIJ OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=1MIJ FirstGlance]. <br>
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or leave the SCENE parameter empty for the default display.
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</td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models|Method:]]</b></td><td class="sblockDat" id="methodDat">X-ray diffraction, [[Resolution|Resolution]] 2.05&#8491;</td></tr>
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<tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=MSE:SELENOMETHIONINE'>MSE</scene></td></tr>
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{{STRUCTURE_1mij| PDB=1mij | SCENE= }}
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<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=1mij FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=1mij OCA], [https://pdbe.org/1mij PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=1mij RCSB], [https://www.ebi.ac.uk/pdbsum/1mij PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=1mij ProSAT]</span></td></tr>
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</table>
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===Crystal Structure of the Homeo-prospero Domain of D. melanogaster Prospero===
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== Function ==
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[https://www.uniprot.org/uniprot/PROS_DROME PROS_DROME] Required for proper neuronal differentiation of most or all neurons and their precursors in central and peripheral nervous systems, axonal outgrowth and pathfinding. Not required for the specification of neuronal identity. May regulate transcription by binding to DNA.<ref>PMID:1720353</ref> <ref>PMID:1842358</ref> <ref>PMID:1540176</ref> <ref>PMID:11051550</ref>
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== Evolutionary Conservation ==
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[[Image:Consurf_key_small.gif|200px|right]]
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The line below this paragraph, {{ABSTRACT_PUBMED_12429095}}, adds the Publication Abstract to the page
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Check<jmol>
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(as it appears on PubMed at http://www.pubmed.gov), where 12429095 is the PubMed ID number.
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<jmolCheckbox>
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<scriptWhenChecked>; select protein; define ~consurf_to_do selected; consurf_initial_scene = true; script "/wiki/ConSurf/mi/1mij_consurf.spt"</scriptWhenChecked>
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{{ABSTRACT_PUBMED_12429095}}
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<scriptWhenUnchecked>script /wiki/extensions/Proteopedia/spt/initialview01.spt</scriptWhenUnchecked>
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<text>to colour the structure by Evolutionary Conservation</text>
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==About this Structure==
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</jmolCheckbox>
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1MIJ is a [[Single protein]] structure of sequence from [http://en.wikipedia.org/wiki/Drosophila_melanogaster Drosophila melanogaster]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=1MIJ OCA].
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</jmol>, as determined by [http://consurfdb.tau.ac.il/ ConSurfDB]. You may read the [[Conservation%2C_Evolutionary|explanation]] of the method and the full data available from [http://bental.tau.ac.il/new_ConSurfDB/main_output.php?pdb_ID=1mij ConSurf].
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<div style="clear:both"></div>
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==Reference==
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== References ==
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Structure of the DNA binding region of prospero reveals a novel homeo-prospero domain., Ryter JM, Doe CQ, Matthews BW, Structure. 2002 Nov;10(11):1541-9. PMID:[http://www.ncbi.nlm.nih.gov/pubmed/12429095 12429095]
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<references/>
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__TOC__
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</StructureSection>
[[Category: Drosophila melanogaster]]
[[Category: Drosophila melanogaster]]
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[[Category: Single protein]]
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[[Category: Large Structures]]
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[[Category: Doe, C Q.]]
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[[Category: Doe CQ]]
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[[Category: Matthews, B W.]]
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[[Category: Matthews BW]]
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[[Category: Ryter, J M.]]
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[[Category: Ryter JM]]
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[[Category: 4-helix bundle]]
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[[Category: Dna-binding domain]]
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[[Category: Homeodomain]]
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[[Category: Prospero domain]]
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''Page seeded by [http://oca.weizmann.ac.il/oca OCA ] on Thu Jul 3 00:02:40 2008''
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Current revision

Crystal Structure of the Homeo-prospero Domain of D. melanogaster Prospero

PDB ID 1mij

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