1mj3

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{{Seed}}
 
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[[Image:1mj3.png|left|200px]]
 
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==Crystal Structure Analysis of rat enoyl-CoA hydratase in complex with hexadienoyl-CoA==
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The line below this paragraph, containing "STRUCTURE_1mj3", creates the "Structure Box" on the page.
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<StructureSection load='1mj3' size='340' side='right'caption='[[1mj3]], [[Resolution|resolution]] 2.10&Aring;' scene=''>
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You may change the PDB parameter (which sets the PDB file loaded into the applet)
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== Structural highlights ==
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or the SCENE parameter (which sets the initial scene displayed when the page is loaded),
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<table><tr><td colspan='2'>[[1mj3]] is a 6 chain structure with sequence from [https://en.wikipedia.org/wiki/Rattus_norvegicus Rattus norvegicus]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=1MJ3 OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=1MJ3 FirstGlance]. <br>
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or leave the SCENE parameter empty for the default display.
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</td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models|Method:]]</b></td><td class="sblockDat" id="methodDat">X-ray diffraction, [[Resolution|Resolution]] 2.1&#8491;</td></tr>
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<tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=HXC:HEXANOYL-COENZYME+A'>HXC</scene></td></tr>
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{{STRUCTURE_1mj3| PDB=1mj3 | SCENE= }}
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<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=1mj3 FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=1mj3 OCA], [https://pdbe.org/1mj3 PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=1mj3 RCSB], [https://www.ebi.ac.uk/pdbsum/1mj3 PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=1mj3 ProSAT]</span></td></tr>
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</table>
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== Function ==
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[https://www.uniprot.org/uniprot/ECHM_RAT ECHM_RAT] Straight-chain enoyl-CoA thioesters from C4 up to at least C16 are processed, although with decreasing catalytic rate.
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== Evolutionary Conservation ==
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[[Image:Consurf_key_small.gif|200px|right]]
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Check<jmol>
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<jmolCheckbox>
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<scriptWhenChecked>; select protein; define ~consurf_to_do selected; consurf_initial_scene = true; script "/wiki/ConSurf/mj/1mj3_consurf.spt"</scriptWhenChecked>
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<scriptWhenUnchecked>script /wiki/extensions/Proteopedia/spt/initialview01.spt</scriptWhenUnchecked>
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<text>to colour the structure by Evolutionary Conservation</text>
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</jmolCheckbox>
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</jmol>, as determined by [http://consurfdb.tau.ac.il/ ConSurfDB]. You may read the [[Conservation%2C_Evolutionary|explanation]] of the method and the full data available from [http://bental.tau.ac.il/new_ConSurfDB/main_output.php?pdb_ID=1mj3 ConSurf].
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<div style="clear:both"></div>
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===Crystal Structure Analysis of rat enoyl-CoA hydratase in complex with hexadienoyl-CoA===
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==See Also==
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*[[Enoyl-CoA hydratase|Enoyl-CoA hydratase]]
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*[[Enoyl-CoA hydratase 3D structures|Enoyl-CoA hydratase 3D structures]]
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__TOC__
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The line below this paragraph, {{ABSTRACT_PUBMED_12445775}}, adds the Publication Abstract to the page
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</StructureSection>
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(as it appears on PubMed at http://www.pubmed.gov), where 12445775 is the PubMed ID number.
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[[Category: Large Structures]]
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{{ABSTRACT_PUBMED_12445775}}
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==About this Structure==
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1MJ3 is a [[Single protein]] structure of sequence from [http://en.wikipedia.org/wiki/Rattus_norvegicus Rattus norvegicus]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=1MJ3 OCA].
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==Reference==
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Stereoselectivity of enoyl-CoA hydratase results from preferential activation of one of two bound substrate conformers., Bell AF, Feng Y, Hofstein HA, Parikh S, Wu J, Rudolph MJ, Kisker C, Whitty A, Tonge PJ, Chem Biol. 2002 Nov;9(11):1247-55. PMID:[http://www.ncbi.nlm.nih.gov/pubmed/12445775 12445775]
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[[Category: Enoyl-CoA hydratase]]
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[[Category: Rattus norvegicus]]
[[Category: Rattus norvegicus]]
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[[Category: Single protein]]
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[[Category: Bell AF]]
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[[Category: Bell, A F.]]
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[[Category: Feng Y]]
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[[Category: Feng, Y.]]
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[[Category: Hofstein HA]]
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[[Category: Hofstein, H A.]]
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[[Category: Kisker C]]
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[[Category: Kisker, C.]]
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[[Category: Parikh S]]
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[[Category: Parikh, S.]]
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[[Category: Rudolph MJ]]
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[[Category: Rudolph, M J.]]
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[[Category: Tonge PJ]]
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[[Category: Tonge, P J.]]
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[[Category: Wu J]]
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[[Category: Wu, J.]]
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[[Category: Homohexamer]]
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''Page seeded by [http://oca.weizmann.ac.il/oca OCA ] on Thu Jul 3 00:05:13 2008''
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Current revision

Crystal Structure Analysis of rat enoyl-CoA hydratase in complex with hexadienoyl-CoA

PDB ID 1mj3

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