1ml5

From Proteopedia

(Difference between revisions)
Jump to: navigation, search
Current revision (07:45, 14 February 2024) (edit) (undo)
 
(14 intermediate revisions not shown.)
Line 1: Line 1:
-
{{Seed}}
 
-
[[Image:1ml5.png|left|200px]]
 
-
<!--
+
==Structure of the E. coli ribosomal termination complex with release factor 2==
-
The line below this paragraph, containing "STRUCTURE_1ml5", creates the "Structure Box" on the page.
+
<SX load='1ml5' size='340' side='right' viewer='molstar' caption='[[1ml5]], [[Resolution|resolution]] 14.00&Aring;' scene=''>
-
You may change the PDB parameter (which sets the PDB file loaded into the applet)
+
== Structural highlights ==
-
or the SCENE parameter (which sets the initial scene displayed when the page is loaded),
+
<table><tr><td colspan='2'>[[1ml5]] is a 10 chain structure with sequence from [https://en.wikipedia.org/wiki/Escherichia_coli Escherichia coli]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=1ML5 OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=1ML5 FirstGlance]. <br>
-
or leave the SCENE parameter empty for the default display.
+
</td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models|Method:]]</b></td><td class="sblockDat" id="methodDat">Electron Microscopy, [[Resolution|Resolution]] 14&#8491;</td></tr>
-
-->
+
<tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=1MA:6-HYDRO-1-METHYLADENOSINE-5-MONOPHOSPHATE'>1MA</scene>, <scene name='pdbligand=2MG:2N-METHYLGUANOSINE-5-MONOPHOSPHATE'>2MG</scene>, <scene name='pdbligand=5MC:5-METHYLCYTIDINE-5-MONOPHOSPHATE'>5MC</scene>, <scene name='pdbligand=5MU:5-METHYLURIDINE+5-MONOPHOSPHATE'>5MU</scene>, <scene name='pdbligand=7MG:7N-METHYL-8-HYDROGUANOSINE-5-MONOPHOSPHATE'>7MG</scene>, <scene name='pdbligand=H2U:5,6-DIHYDROURIDINE-5-MONOPHOSPHATE'>H2U</scene>, <scene name='pdbligand=M2G:N2-DIMETHYLGUANOSINE-5-MONOPHOSPHATE'>M2G</scene>, <scene name='pdbligand=OMC:O2-METHYLYCYTIDINE-5-MONOPHOSPHATE'>OMC</scene>, <scene name='pdbligand=OMG:O2-METHYLGUANOSINE-5-MONOPHOSPHATE'>OMG</scene>, <scene name='pdbligand=PSU:PSEUDOURIDINE-5-MONOPHOSPHATE'>PSU</scene>, <scene name='pdbligand=YG:WYBUTOSINE'>YG</scene></td></tr>
-
{{STRUCTURE_1ml5| PDB=1ml5 | SCENE= }}
+
<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=1ml5 FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=1ml5 OCA], [https://pdbe.org/1ml5 PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=1ml5 RCSB], [https://www.ebi.ac.uk/pdbsum/1ml5 PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=1ml5 ProSAT]</span></td></tr>
 +
</table>
 +
== Function ==
 +
[https://www.uniprot.org/uniprot/RF2_ECOLI RF2_ECOLI] Peptide chain release factor 2 directs the termination of translation in response to the peptide chain termination codons UGA and UAA.[HAMAP-Rule:MF_00094]
 +
== Evolutionary Conservation ==
 +
[[Image:Consurf_key_small.gif|200px|right]]
 +
Check<jmol>
 +
<jmolCheckbox>
 +
<scriptWhenChecked>; select protein; define ~consurf_to_do selected; consurf_initial_scene = true; script "/wiki/ConSurf/ml/1ml5_consurf.spt"</scriptWhenChecked>
 +
<scriptWhenUnchecked>script /wiki/extensions/Proteopedia/spt/initialview01.spt</scriptWhenUnchecked>
 +
<text>to colour the structure by Evolutionary Conservation</text>
 +
</jmolCheckbox>
 +
</jmol>, as determined by [http://consurfdb.tau.ac.il/ ConSurfDB]. You may read the [[Conservation%2C_Evolutionary|explanation]] of the method and the full data available from [http://bental.tau.ac.il/new_ConSurfDB/main_output.php?pdb_ID=1ml5 ConSurf].
 +
<div style="clear:both"></div>
-
===Structure of the E. coli ribosomal termination complex with release factor 2===
+
==See Also==
-
 
+
*[[MHC 3D structures|MHC 3D structures]]
-
 
+
*[[MHC I 3D structures|MHC I 3D structures]]
-
<!--
+
*[[Ribosomal protein THX 3D structures|Ribosomal protein THX 3D structures]]
-
The line below this paragraph, {{ABSTRACT_PUBMED_12511961}}, adds the Publication Abstract to the page
+
*[[Transfer RNA (tRNA)|Transfer RNA (tRNA)]]
-
(as it appears on PubMed at http://www.pubmed.gov), where 12511961 is the PubMed ID number.
+
__TOC__
-
-->
+
</SX>
-
{{ABSTRACT_PUBMED_12511961}}
+
-
 
+
-
==About this Structure==
+
-
1ML5 is a [[Single protein]] structure of sequence from [http://en.wikipedia.org/wiki/Escherichia_coli Escherichia coli]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=1ML5 OCA].
+
-
 
+
-
==Reference==
+
-
Structure of the Escherichia coli ribosomal termination complex with release factor 2., Klaholz BP, Pape T, Zavialov AV, Myasnikov AG, Orlova EV, Vestergaard B, Ehrenberg M, van Heel M, Nature. 2003 Jan 2;421(6918):90-4. PMID:[http://www.ncbi.nlm.nih.gov/pubmed/12511961 12511961]
+
[[Category: Escherichia coli]]
[[Category: Escherichia coli]]
-
[[Category: Single protein]]
+
[[Category: Large Structures]]
-
[[Category: Ehrenberg, M.]]
+
[[Category: Ehrenberg M]]
-
[[Category: Heel, M van.]]
+
[[Category: Klaholz BP]]
-
[[Category: Klaholz, B P.]]
+
[[Category: Myasnikov AG]]
-
[[Category: Myasnikov, A G.]]
+
[[Category: Orlova EV]]
-
[[Category: Orlova, E V.]]
+
[[Category: Pape T]]
-
[[Category: Pape, T.]]
+
[[Category: Vestergaard B]]
-
[[Category: Vestergaard, B.]]
+
[[Category: Zavialov AV]]
-
[[Category: Zavialov, A V.]]
+
[[Category: Van Heel M]]
-
[[Category: Angular reconstitution]]
+
-
[[Category: Cryo-eletron microscopy]]
+
-
[[Category: E. coli]]
+
-
[[Category: Release factor]]
+
-
[[Category: Ribosome]]
+
-
[[Category: Termination of protein synthesis]]
+
-
 
+
-
''Page seeded by [http://oca.weizmann.ac.il/oca OCA ] on Thu Jul 3 00:14:30 2008''
+

Current revision

Structure of the E. coli ribosomal termination complex with release factor 2

1ml5, resolution 14.00Å

Proteopedia Page Contributors and Editors (what is this?)

OCA

Retrieved from "http://52.214.119.220/wiki/index.php/1ml5"
Personal tools