1mmi

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{{Seed}}
 
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[[Image:1mmi.png|left|200px]]
 
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==E. COLI DNA POLYMERASE BETA SUBUNIT==
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The line below this paragraph, containing "STRUCTURE_1mmi", creates the "Structure Box" on the page.
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<StructureSection load='1mmi' size='340' side='right'caption='[[1mmi]], [[Resolution|resolution]] 1.85&Aring;' scene=''>
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You may change the PDB parameter (which sets the PDB file loaded into the applet)
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== Structural highlights ==
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or the SCENE parameter (which sets the initial scene displayed when the page is loaded),
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<table><tr><td colspan='2'>[[1mmi]] is a 2 chain structure with sequence from [https://en.wikipedia.org/wiki/Escherichia_coli Escherichia coli]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=1MMI OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=1MMI FirstGlance]. <br>
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or leave the SCENE parameter empty for the default display.
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</td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models|Method:]]</b></td><td class="sblockDat" id="methodDat">X-ray diffraction, [[Resolution|Resolution]] 1.848&#8491;</td></tr>
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<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=1mmi FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=1mmi OCA], [https://pdbe.org/1mmi PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=1mmi RCSB], [https://www.ebi.ac.uk/pdbsum/1mmi PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=1mmi ProSAT]</span></td></tr>
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{{STRUCTURE_1mmi| PDB=1mmi | SCENE= }}
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</table>
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== Function ==
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[https://www.uniprot.org/uniprot/DPO3B_ECOLI DPO3B_ECOLI] DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. This DNA polymerase also exhibits 3' to 5' exonuclease activity. The beta chain is required for initiation of replication once it is clamped onto DNA, it slides freely (bidirectional and ATP-independent) along duplex DNA.
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== Evolutionary Conservation ==
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[[Image:Consurf_key_small.gif|200px|right]]
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Check<jmol>
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<jmolCheckbox>
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<scriptWhenChecked>; select protein; define ~consurf_to_do selected; consurf_initial_scene = true; script "/wiki/ConSurf/mm/1mmi_consurf.spt"</scriptWhenChecked>
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<scriptWhenUnchecked>script /wiki/extensions/Proteopedia/spt/initialview01.spt</scriptWhenUnchecked>
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<text>to colour the structure by Evolutionary Conservation</text>
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</jmolCheckbox>
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</jmol>, as determined by [http://consurfdb.tau.ac.il/ ConSurfDB]. You may read the [[Conservation%2C_Evolutionary|explanation]] of the method and the full data available from [http://bental.tau.ac.il/new_ConSurfDB/main_output.php?pdb_ID=1mmi ConSurf].
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<div style="clear:both"></div>
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===E. COLI DNA POLYMERASE BETA SUBUNIT===
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==See Also==
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*[[DNA polymerase 3D structures|DNA polymerase 3D structures]]
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__TOC__
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</StructureSection>
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The line below this paragraph, {{ABSTRACT_PUBMED_12832762}}, adds the Publication Abstract to the page
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(as it appears on PubMed at http://www.pubmed.gov), where 12832762 is the PubMed ID number.
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{{ABSTRACT_PUBMED_12832762}}
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==About this Structure==
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1MMI is a [[Single protein]] structure of sequence from [http://en.wikipedia.org/wiki/Escherichia_coli Escherichia coli]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=1MMI OCA].
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==Reference==
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Flexibility revealed by the 1.85 A crystal structure of the beta sliding-clamp subunit of Escherichia coli DNA polymerase III., Oakley AJ, Prosselkov P, Wijffels G, Beck JL, Wilce MC, Dixon NE, Acta Crystallogr D Biol Crystallogr. 2003 Jul;59(Pt 7):1192-9. Epub 2003, Jun 27. PMID:[http://www.ncbi.nlm.nih.gov/pubmed/12832762 12832762]
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[[Category: DNA-directed DNA polymerase]]
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[[Category: Escherichia coli]]
[[Category: Escherichia coli]]
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[[Category: Single protein]]
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[[Category: Large Structures]]
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[[Category: Beck, J L.]]
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[[Category: Beck JL]]
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[[Category: Dixon, N E.]]
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[[Category: Dixon NE]]
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[[Category: Oakley, A J.]]
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[[Category: Oakley AJ]]
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[[Category: Prosselkov, P.]]
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[[Category: Prosselkov P]]
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[[Category: Wijffels, G.]]
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[[Category: Wijffels G]]
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[[Category: Wilce, M C.J.]]
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[[Category: Wilce MCJ]]
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[[Category: Dna polymerase beta subunit]]
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[[Category: Dna replication]]
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[[Category: E. coli]]
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[[Category: Processivity factor]]
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[[Category: Sliding clamp]]
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''Page seeded by [http://oca.weizmann.ac.il/oca OCA ] on Thu Jul 3 00:22:46 2008''
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Current revision

E. COLI DNA POLYMERASE BETA SUBUNIT

PDB ID 1mmi

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OCA

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