This old version of Proteopedia is provided for student assignments while the new version is undergoing repairs. Content and edits done in this old version of Proteopedia after March 1, 2026 will eventually be lost when it is retired in about June of 2026.


Apply for new accounts at the new Proteopedia. Your logins will work in both the old and new versions.


1mo9

From Proteopedia

(Difference between revisions)
Jump to: navigation, search
Current revision (08:38, 10 April 2024) (edit) (undo)
 
(11 intermediate revisions not shown.)
Line 1: Line 1:
-
{{Seed}}
 
-
[[Image:1mo9.png|left|200px]]
 
-
<!--
+
==NADPH DEPENDENT 2-KETOPROPYL COENZYME M OXIDOREDUCTASE/CARBOXYLASE COMPLEXED WITH 2-KETOPROPYL COENZYME M==
-
The line below this paragraph, containing "STRUCTURE_1mo9", creates the "Structure Box" on the page.
+
<StructureSection load='1mo9' size='340' side='right'caption='[[1mo9]], [[Resolution|resolution]] 1.65&Aring;' scene=''>
-
You may change the PDB parameter (which sets the PDB file loaded into the applet)
+
== Structural highlights ==
-
or the SCENE parameter (which sets the initial scene displayed when the page is loaded),
+
<table><tr><td colspan='2'>[[1mo9]] is a 2 chain structure with sequence from [https://en.wikipedia.org/wiki/Xanthobacter_autotrophicus_Py2 Xanthobacter autotrophicus Py2]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=1MO9 OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=1MO9 FirstGlance]. <br>
-
or leave the SCENE parameter empty for the default display.
+
</td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models|Method:]]</b></td><td class="sblockDat" id="methodDat">X-ray diffraction, [[Resolution|Resolution]] 1.65&#8491;</td></tr>
-
-->
+
<tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=FAD:FLAVIN-ADENINE+DINUCLEOTIDE'>FAD</scene>, <scene name='pdbligand=KPC:(2-[2-KETOPROPYLTHIO]ETHANESULFONATE'>KPC</scene></td></tr>
-
{{STRUCTURE_1mo9| PDB=1mo9 | SCENE= }}
+
<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=1mo9 FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=1mo9 OCA], [https://pdbe.org/1mo9 PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=1mo9 RCSB], [https://www.ebi.ac.uk/pdbsum/1mo9 PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=1mo9 ProSAT]</span></td></tr>
-
 
+
</table>
-
===NADPH DEPENDENT 2-KETOPROPYL COENZYME M OXIDOREDUCTASE/CARBOXYLASE COMPLEXED WITH 2-KETOPROPYL COENZYME M===
+
== Function ==
-
 
+
[https://www.uniprot.org/uniprot/XECC_XANP2 XECC_XANP2] Catalyzes the reductive cleavage of the thioether linkage of 2-ketopropyl-coenzyme M, and the subsequent carboxylation of the ketopropyl cleavage product, yielding the products acetoacetate and free coenzyme M.
-
 
+
== Evolutionary Conservation ==
-
<!--
+
[[Image:Consurf_key_small.gif|200px|right]]
-
The line below this paragraph, {{ABSTRACT_PUBMED_12390015}}, adds the Publication Abstract to the page
+
Check<jmol>
-
(as it appears on PubMed at http://www.pubmed.gov), where 12390015 is the PubMed ID number.
+
<jmolCheckbox>
-
-->
+
<scriptWhenChecked>; select protein; define ~consurf_to_do selected; consurf_initial_scene = true; script "/wiki/ConSurf/mo/1mo9_consurf.spt"</scriptWhenChecked>
-
{{ABSTRACT_PUBMED_12390015}}
+
<scriptWhenUnchecked>script /wiki/extensions/Proteopedia/spt/initialview01.spt</scriptWhenUnchecked>
-
 
+
<text>to colour the structure by Evolutionary Conservation</text>
-
==About this Structure==
+
</jmolCheckbox>
-
1MO9 is a [[Single protein]] structure of sequence from [http://en.wikipedia.org/wiki/Xanthobacter_sp. Xanthobacter sp.]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=1MO9 OCA].
+
</jmol>, as determined by [http://consurfdb.tau.ac.il/ ConSurfDB]. You may read the [[Conservation%2C_Evolutionary|explanation]] of the method and the full data available from [http://bental.tau.ac.il/new_ConSurfDB/main_output.php?pdb_ID=1mo9 ConSurf].
-
 
+
<div style="clear:both"></div>
-
==Reference==
+
__TOC__
-
Structural basis for CO2 fixation by a novel member of the disulfide oxidoreductase family of enzymes, 2-ketopropyl-coenzyme M oxidoreductase/carboxylase., Nocek B, Jang SB, Jeong MS, Clark DD, Ensign SA, Peters JW, Biochemistry. 2002 Oct 29;41(43):12907-13. PMID:[http://www.ncbi.nlm.nih.gov/pubmed/12390015 12390015]
+
</StructureSection>
-
[[Category: Single protein]]
+
[[Category: Large Structures]]
-
[[Category: Xanthobacter sp.]]
+
[[Category: Xanthobacter autotrophicus Py2]]
-
[[Category: Clark, D D.]]
+
[[Category: Clark DD]]
-
[[Category: Ensign, S A.]]
+
[[Category: Ensign SA]]
-
[[Category: Jang, S B.]]
+
[[Category: Jang SB]]
-
[[Category: Jeong, M S.]]
+
[[Category: Jeong MS]]
-
[[Category: Nocek, B.]]
+
[[Category: Nocek B]]
-
[[Category: Peters, J W.]]
+
[[Category: Peters JW]]
-
[[Category: Disulphide bond]]
+
-
[[Category: Nucleotide binding domain]]
+
-
[[Category: Nucleotide binding motif]]
+
-
 
+
-
''Page seeded by [http://oca.weizmann.ac.il/oca OCA ] on Thu Jul 3 00:32:40 2008''
+

Current revision

NADPH DEPENDENT 2-KETOPROPYL COENZYME M OXIDOREDUCTASE/CARBOXYLASE COMPLEXED WITH 2-KETOPROPYL COENZYME M

PDB ID 1mo9

Drag the structure with the mouse to rotate

Proteopedia Page Contributors and Editors (what is this?)

OCA

Personal tools