2vor

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{{Seed}}
 
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[[Image:2vor.jpg|left|200px]]
 
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==Crystal Structures of Mycobacterium tuberculosis Folylpolyglutamate Synthase Complexed with ADP and AMPPCP==
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The line below this paragraph, containing "STRUCTURE_2vor", creates the "Structure Box" on the page.
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<StructureSection load='2vor' size='340' side='right'caption='[[2vor]], [[Resolution|resolution]] 2.30&Aring;' scene=''>
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You may change the PDB parameter (which sets the PDB file loaded into the applet)
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== Structural highlights ==
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or the SCENE parameter (which sets the initial scene displayed when the page is loaded),
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<table><tr><td colspan='2'>[[2vor]] is a 1 chain structure with sequence from [https://en.wikipedia.org/wiki/Mycobacterium_tuberculosis_H37Rv Mycobacterium tuberculosis H37Rv]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=2VOR OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=2VOR FirstGlance]. <br>
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or leave the SCENE parameter empty for the default display.
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</td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models|Method:]]</b></td><td class="sblockDat" id="methodDat">X-ray diffraction, [[Resolution|Resolution]] 2.3&#8491;</td></tr>
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<tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=ACP:PHOSPHOMETHYLPHOSPHONIC+ACID+ADENYLATE+ESTER'>ACP</scene>, <scene name='pdbligand=CO:COBALT+(II)+ION'>CO</scene>, <scene name='pdbligand=GOL:GLYCEROL'>GOL</scene></td></tr>
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{{STRUCTURE_2vor| PDB=2vor | SCENE= }}
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<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=2vor FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=2vor OCA], [https://pdbe.org/2vor PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=2vor RCSB], [https://www.ebi.ac.uk/pdbsum/2vor PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=2vor ProSAT]</span></td></tr>
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</table>
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== Function ==
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[https://www.uniprot.org/uniprot/O53174_MYCTO O53174_MYCTO]
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== Evolutionary Conservation ==
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[[Image:Consurf_key_small.gif|200px|right]]
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Check<jmol>
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<jmolCheckbox>
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<scriptWhenChecked>; select protein; define ~consurf_to_do selected; consurf_initial_scene = true; script "/wiki/ConSurf/vo/2vor_consurf.spt"</scriptWhenChecked>
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<scriptWhenUnchecked>script /wiki/extensions/Proteopedia/spt/initialview01.spt</scriptWhenUnchecked>
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<text>to colour the structure by Evolutionary Conservation</text>
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</jmolCheckbox>
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</jmol>, as determined by [http://consurfdb.tau.ac.il/ ConSurfDB]. You may read the [[Conservation%2C_Evolutionary|explanation]] of the method and the full data available from [http://bental.tau.ac.il/new_ConSurfDB/main_output.php?pdb_ID=2vor ConSurf].
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<div style="clear:both"></div>
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===CRYSTAL STRUCTURES OF MYCOBACTERIUM TUBERCULOSIS FOLYLPOLYGLUTAMATE SYNTHASE COMPLEXED WITH ADP AND AMPPCP===
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==See Also==
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*[[Folylpolyglutamate synthase|Folylpolyglutamate synthase]]
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__TOC__
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</StructureSection>
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The line below this paragraph, {{ABSTRACT_PUBMED_18566510}}, adds the Publication Abstract to the page
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[[Category: Large Structures]]
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(as it appears on PubMed at http://www.pubmed.gov), where 18566510 is the PubMed ID number.
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[[Category: Mycobacterium tuberculosis H37Rv]]
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[[Category: Baker EN]]
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{{ABSTRACT_PUBMED_18566510}}
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[[Category: Metcalf P]]
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[[Category: Smith CA]]
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==About this Structure==
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[[Category: Young PG]]
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2VOR is a [[Single protein]] structure of sequence from [http://en.wikipedia.org/wiki/Mycobacterium_tuberculosis Mycobacterium tuberculosis]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=2VOR OCA].
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==Reference==
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Structures of Mycobacterium tuberculosisfolylpolyglutamate synthase complexed with ADP and AMPPCP., Young PG, Smith CA, Metcalf P, Baker EN, Acta Crystallogr D Biol Crystallogr. 2008 Jul;64(Pt 7):745-53. Epub 2008, Jun 18. PMID:[http://www.ncbi.nlm.nih.gov/pubmed/18566510 18566510]
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[[Category: Mycobacterium tuberculosis]]
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[[Category: Single protein]]
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[[Category: Tetrahydrofolate synthase]]
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[[Category: Baker, E N.]]
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[[Category: Metcalf, P.]]
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[[Category: Smith, C A.]]
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[[Category: Young, P G.]]
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[[Category: Atp-binding]]
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[[Category: Cell cycle]]
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[[Category: Cell division]]
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[[Category: Cell shape]]
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[[Category: Cell wall biogenesis/degradation]]
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[[Category: Cobalt binding]]
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[[Category: Conformational change]]
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[[Category: Folate metabolism]]
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[[Category: Ligase]]
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[[Category: Nucleotide binding]]
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[[Category: Nucleotide-binding]]
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[[Category: Peptidoglycan synthesis]]
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''Page seeded by [http://oca.weizmann.ac.il/oca OCA ] on Thu Jul 3 11:23:23 2008''
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Current revision

Crystal Structures of Mycobacterium tuberculosis Folylpolyglutamate Synthase Complexed with ADP and AMPPCP

PDB ID 2vor

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