439d
From Proteopedia
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| - | {{Seed}} | ||
| - | [[Image:439d.png|left|200px]] | ||
| - | + | ==5'-R(*CP*UP*GP*GP*GP*CP*GP*G)-3', 5'-R(*CP*CP*GP*CP*CP*UP*GP*G)-3'== | |
| - | + | <StructureSection load='439d' size='340' side='right'caption='[[439d]], [[Resolution|resolution]] 1.60Å' scene=''> | |
| - | + | == Structural highlights == | |
| - | + | <table><tr><td colspan='2'>[[439d]] is a 2 chain structure. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=439D OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=439D FirstGlance]. <br> | |
| - | + | </td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models|Method:]]</b></td><td class="sblockDat" id="methodDat">X-ray diffraction, [[Resolution|Resolution]] 1.6Å</td></tr> | |
| - | -- | + | <tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=BA:BARIUM+ION'>BA</scene></td></tr> |
| - | + | <tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=439d FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=439d OCA], [https://pdbe.org/439d PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=439d RCSB], [https://www.ebi.ac.uk/pdbsum/439d PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=439d ProSAT]</span></td></tr> | |
| + | </table> | ||
| + | <div style="background-color:#fffaf0;"> | ||
| + | == Publication Abstract from PubMed == | ||
| + | The structure of the RNA duplex r(CUGGGCGG).r(CCGCCUGG) has been determined at 1.6 A resolution and refined to a final R factor of 18.3% (R(free) = 24.1%). The sequence of the RNA fragment resembles domain E of Thermus flavus 5S rRNA. A previously undescribed wobble-like G.C base-pair formation is found. Owing to the observed hydrogen-bond network, it is proposed that the cytosine is protonated at position N3. The unusual base-pair formation is presumably strained by intermolecular interactions. In this context, crystal packing and particular intermolecular contacts may have direct influence on the three-dimensional structure. Furthermore, this structure includes two G.U wobble base pairs in tandem conformation, with the purines forming a so-called 'cross-strand G stack'. | ||
| - | + | Structure of an RNA duplex with an unusual G.C pair in wobble-like conformation at 1.6 A resolution.,Perbandt M, Vallazza M, Lippmann C, Betzel C, Erdmann VA Acta Crystallogr D Biol Crystallogr. 2001 Feb;57(Pt 2):219-24. PMID:11173467<ref>PMID:11173467</ref> | |
| - | + | From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine.<br> | |
| - | + | </div> | |
| - | + | <div class="pdbe-citations 439d" style="background-color:#fffaf0;"></div> | |
| - | + | == References == | |
| - | --> | + | <references/> |
| - | + | __TOC__ | |
| - | + | </StructureSection> | |
| - | == | + | [[Category: Large Structures]] |
| - | + | [[Category: Betzel C]] | |
| - | + | [[Category: Erdmann VA]] | |
| - | + | [[Category: Lorenz S]] | |
| - | + | [[Category: Perbandt M]] | |
| - | [[Category: Betzel | + | [[Category: Vallazza M]] |
| - | [[Category: Erdmann | + | |
| - | [[Category: Lorenz | + | |
| - | [[Category: Perbandt | + | |
| - | [[Category: Vallazza | + | |
| - | + | ||
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Current revision
5'-R(*CP*UP*GP*GP*GP*CP*GP*G)-3', 5'-R(*CP*CP*GP*CP*CP*UP*GP*G)-3'
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