4ame

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{{Seed}}
 
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[[Image:4ame.png|left|200px]]
 
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==TYPE III ANTIFREEZE PROTEIN ISOFORM HPLC 12 T18A==
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The line below this paragraph, containing "STRUCTURE_4ame", creates the "Structure Box" on the page.
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<StructureSection load='4ame' size='340' side='right'caption='[[4ame]], [[Resolution|resolution]] 2.05&Aring;' scene=''>
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You may change the PDB parameter (which sets the PDB file loaded into the applet)
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== Structural highlights ==
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or the SCENE parameter (which sets the initial scene displayed when the page is loaded),
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<table><tr><td colspan='2'>[[4ame]] is a 1 chain structure with sequence from [https://en.wikipedia.org/wiki/Zoarces_americanus Zoarces americanus]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=4AME OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=4AME FirstGlance]. <br>
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or leave the SCENE parameter empty for the default display.
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</td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models|Method:]]</b></td><td class="sblockDat" id="methodDat">X-ray diffraction, [[Resolution|Resolution]] 2.05&#8491;</td></tr>
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<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=4ame FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=4ame OCA], [https://pdbe.org/4ame PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=4ame RCSB], [https://www.ebi.ac.uk/pdbsum/4ame PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=4ame ProSAT]</span></td></tr>
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{{STRUCTURE_4ame| PDB=4ame | SCENE= }}
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</table>
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== Function ==
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[https://www.uniprot.org/uniprot/ANP12_ZOAAM ANP12_ZOAAM] Contributes to protect fish blood from freezing at subzero sea water temperatures. Lowers the blood freezing point. Binds to nascent ice crystals and prevents further growth.
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== Evolutionary Conservation ==
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[[Image:Consurf_key_small.gif|200px|right]]
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Check<jmol>
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<jmolCheckbox>
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<scriptWhenChecked>; select protein; define ~consurf_to_do selected; consurf_initial_scene = true; script "/wiki/ConSurf/am/4ame_consurf.spt"</scriptWhenChecked>
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<scriptWhenUnchecked>script /wiki/extensions/Proteopedia/spt/initialview01.spt</scriptWhenUnchecked>
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<text>to colour the structure by Evolutionary Conservation</text>
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</jmolCheckbox>
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</jmol>, as determined by [http://consurfdb.tau.ac.il/ ConSurfDB]. You may read the [[Conservation%2C_Evolutionary|explanation]] of the method and the full data available from [http://bental.tau.ac.il/new_ConSurfDB/main_output.php?pdb_ID=4ame ConSurf].
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<div style="clear:both"></div>
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===TYPE III ANTIFREEZE PROTEIN ISOFORM HPLC 12 T18A===
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==See Also==
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*[[Antifreeze protein 3D structures|Antifreeze protein 3D structures]]
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__TOC__
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</StructureSection>
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The line below this paragraph, {{ABSTRACT_PUBMED_10207002}}, adds the Publication Abstract to the page
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[[Category: Large Structures]]
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(as it appears on PubMed at http://www.pubmed.gov), where 10207002 is the PubMed ID number.
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[[Category: Zoarces americanus]]
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[[Category: Baardsnes J]]
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{{ABSTRACT_PUBMED_10207002}}
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[[Category: Davies PL]]
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[[Category: Deluca CI]]
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==About this Structure==
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[[Category: Graether SP]]
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4AME is a [[Single protein]] structure of sequence from [http://en.wikipedia.org/wiki/Macrozoarces_americanus Macrozoarces americanus]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=4AME OCA].
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[[Category: Hill GA]]
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[[Category: Jia Z]]
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==Reference==
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Quantitative and qualitative analysis of type III antifreeze protein structure and function., Graether SP, DeLuca CI, Baardsnes J, Hill GA, Davies PL, Jia Z, J Biol Chem. 1999 Apr 23;274(17):11842-7. PMID:[http://www.ncbi.nlm.nih.gov/pubmed/10207002 10207002]
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[[Category: Macrozoarces americanus]]
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[[Category: Single protein]]
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[[Category: Baardsnes, J.]]
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[[Category: Davies, P L.]]
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[[Category: Deluca, C I.]]
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[[Category: Graether, S P.]]
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[[Category: Hill, G A.]]
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[[Category: Jia, Z.]]
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[[Category: Antifreeze protein]]
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[[Category: Ice binding protein]]
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[[Category: Mutant]]
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[[Category: Thermal hysteresis protein]]
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''Page seeded by [http://oca.weizmann.ac.il/oca OCA ] on Thu Jul 3 13:28:10 2008''
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TYPE III ANTIFREEZE PROTEIN ISOFORM HPLC 12 T18A

PDB ID 4ame

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