4mon

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{{Seed}}
 
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[[Image:4mon.png|left|200px]]
 
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==ORTHORHOMBIC MONELLIN==
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The line below this paragraph, containing "STRUCTURE_4mon", creates the "Structure Box" on the page.
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<StructureSection load='4mon' size='340' side='right'caption='[[4mon]], [[Resolution|resolution]] 2.30&Aring;' scene=''>
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== Structural highlights ==
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or the SCENE parameter (which sets the initial scene displayed when the page is loaded),
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<table><tr><td colspan='2'>[[4mon]] is a 4 chain structure with sequence from [https://en.wikipedia.org/wiki/Dioscoreophyllum_cumminsii Dioscoreophyllum cumminsii]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=4MON OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=4MON FirstGlance]. <br>
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</td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models|Method:]]</b></td><td class="sblockDat" id="methodDat">X-ray diffraction, [[Resolution|Resolution]] 2.3&#8491;</td></tr>
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<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=4mon FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=4mon OCA], [https://pdbe.org/4mon PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=4mon RCSB], [https://www.ebi.ac.uk/pdbsum/4mon PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=4mon ProSAT]</span></td></tr>
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{{STRUCTURE_4mon| PDB=4mon | SCENE= }}
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</table>
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== Function ==
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[https://www.uniprot.org/uniprot/MONA_DIOCU MONA_DIOCU] Taste-modifying protein; intensely sweet-tasting protein.
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<div style="background-color:#fffaf0;">
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== Publication Abstract from PubMed ==
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The structure of orthorhombic crystals of monellin, a sweet protein extracted from African serendipity berries, has been solved by molecular replacement and refined to 2.3 A resolution. The final R factor was 0.150 for a model with excellent geometry. A monellin molecule consists of two peptides that are non-covalently bound, with chain A composed of three beta-strands interconnected by loop regions and chain B composed of two beta-strands interconnected by an alpha-helix. The N terminus of chain A is in close proximity to the C terminus of chain B. The two molecules in the asymmetric unit are related by a non-crystallographic twofold axis and form a dimer, similar to those previously observed in other crystal forms of both natural and single-chain monellin. The r.m.s, deviation between the Calpha atoms in the two independent molecules is 0.60 A, while the deviations from the individual molecules in the previously reported monoclinic crystals are 0.50-0.57 A. This result proves that the structure of monellin is not significantly influenced by crystal packing forces.
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===ORTHORHOMBIC MONELLIN===
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Structure of monellin refined to 2.3 a resolution in the orthorhombic crystal form.,Bujacz G, Miller M, Harrison R, Thanki N, Gilliland GL, Ogata CM, Kim SH, Wlodawer A Acta Crystallogr D Biol Crystallogr. 1997 Nov 1;53(Pt 6):713-9. PMID:15299859<ref>PMID:15299859</ref>
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From MEDLINE&reg;/PubMed&reg;, a database of the U.S. National Library of Medicine.<br>
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<div class="pdbe-citations 4mon" style="background-color:#fffaf0;"></div>
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(as it appears on PubMed at http://www.pubmed.gov), where 15299859 is the PubMed ID number.
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== References ==
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<references/>
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{{ABSTRACT_PUBMED_15299859}}
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__TOC__
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</StructureSection>
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==About this Structure==
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4MON is a [[Protein complex]] structure of sequences from [http://en.wikipedia.org/wiki/Dioscoreophyllum_cumminsii Dioscoreophyllum cumminsii]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=4MON OCA].
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==Reference==
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Structure of monellin refined to 2.3 a resolution in the orthorhombic crystal form., Bujacz G, Miller M, Harrison R, Thanki N, Gilliland GL, Ogata CM, Kim SH, Wlodawer A, Acta Crystallogr D Biol Crystallogr. 1997 Nov 1;53(Pt 6):713-9. PMID:[http://www.ncbi.nlm.nih.gov/pubmed/15299859 15299859]
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[[Category: Dioscoreophyllum cumminsii]]
[[Category: Dioscoreophyllum cumminsii]]
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[[Category: Protein complex]]
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[[Category: Large Structures]]
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[[Category: Bujacz, G.]]
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[[Category: Bujacz G]]
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[[Category: Wlodawer, A.]]
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[[Category: Wlodawer A]]
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[[Category: Orthorhombic crystal]]
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[[Category: Sweet-tasting protein]]
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''Page seeded by [http://oca.weizmann.ac.il/oca OCA ] on Thu Jul 3 13:44:31 2008''
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ORTHORHOMBIC MONELLIN

PDB ID 4mon

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