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5tgl

From Proteopedia

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{{Seed}}
 
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[[Image:5tgl.png|left|200px]]
 
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==A MODEL FOR INTERFACIAL ACTIVATION IN LIPASES FROM THE STRUCTURE OF A FUNGAL LIPASE-INHIBITOR COMPLEX==
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The line below this paragraph, containing "STRUCTURE_5tgl", creates the "Structure Box" on the page.
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<StructureSection load='5tgl' size='340' side='right'caption='[[5tgl]], [[Resolution|resolution]] 3.00&Aring;' scene=''>
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You may change the PDB parameter (which sets the PDB file loaded into the applet)
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== Structural highlights ==
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or the SCENE parameter (which sets the initial scene displayed when the page is loaded),
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<table><tr><td colspan='2'>[[5tgl]] is a 1 chain structure with sequence from [https://en.wikipedia.org/wiki/Rhizomucor_miehei Rhizomucor miehei]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=5TGL OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=5TGL FirstGlance]. <br>
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or leave the SCENE parameter empty for the default display.
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</td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models|Method:]]</b></td><td class="sblockDat" id="methodDat">X-ray diffraction, [[Resolution|Resolution]] 3&#8491;</td></tr>
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<tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=HEE:N-HEXYLPHOSPHONATE+ETHYL+ESTER'>HEE</scene></td></tr>
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{{STRUCTURE_5tgl| PDB=5tgl | SCENE= }}
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<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=5tgl FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=5tgl OCA], [https://pdbe.org/5tgl PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=5tgl RCSB], [https://www.ebi.ac.uk/pdbsum/5tgl PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=5tgl ProSAT]</span></td></tr>
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</table>
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== Function ==
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[https://www.uniprot.org/uniprot/LIP_RHIMI LIP_RHIMI]
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== Evolutionary Conservation ==
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[[Image:Consurf_key_small.gif|200px|right]]
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Check<jmol>
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<jmolCheckbox>
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<scriptWhenChecked>; select protein; define ~consurf_to_do selected; consurf_initial_scene = true; script "/wiki/ConSurf/tg/5tgl_consurf.spt"</scriptWhenChecked>
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<scriptWhenUnchecked>script /wiki/extensions/Proteopedia/spt/initialview01.spt</scriptWhenUnchecked>
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<text>to colour the structure by Evolutionary Conservation</text>
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</jmolCheckbox>
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</jmol>, as determined by [http://consurfdb.tau.ac.il/ ConSurfDB]. You may read the [[Conservation%2C_Evolutionary|explanation]] of the method and the full data available from [http://bental.tau.ac.il/new_ConSurfDB/main_output.php?pdb_ID=5tgl ConSurf].
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<div style="clear:both"></div>
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===A MODEL FOR INTERFACIAL ACTIVATION IN LIPASES FROM THE STRUCTURE OF A FUNGAL LIPASE-INHIBITOR COMPLEX===
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==See Also==
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*[[Lipase 3D Structures|Lipase 3D Structures]]
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__TOC__
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</StructureSection>
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The line below this paragraph, {{ABSTRACT_PUBMED_2046751}}, adds the Publication Abstract to the page
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[[Category: Large Structures]]
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(as it appears on PubMed at http://www.pubmed.gov), where 2046751 is the PubMed ID number.
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{{ABSTRACT_PUBMED_2046751}}
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==About this Structure==
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5TGL is a [[Single protein]] structure of sequence from [http://en.wikipedia.org/wiki/Rhizomucor_miehei Rhizomucor miehei]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=5TGL OCA].
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==Reference==
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A model for interfacial activation in lipases from the structure of a fungal lipase-inhibitor complex., Brzozowski AM, Derewenda U, Derewenda ZS, Dodson GG, Lawson DM, Turkenburg JP, Bjorkling F, Huge-Jensen B, Patkar SA, Thim L, Nature. 1991 Jun 6;351(6326):491-4. PMID:[http://www.ncbi.nlm.nih.gov/pubmed/2046751 2046751]
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[[Category: Rhizomucor miehei]]
[[Category: Rhizomucor miehei]]
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[[Category: Single protein]]
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[[Category: Bjorkling F]]
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[[Category: Triacylglycerol lipase]]
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[[Category: Brzozowski AM]]
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[[Category: Bjorkling, F.]]
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[[Category: Derewenda U]]
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[[Category: Brzozowski, A M.]]
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[[Category: Derewenda ZS]]
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[[Category: Derewenda, U.]]
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[[Category: Dodson GG]]
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[[Category: Derewenda, Z S.]]
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[[Category: Huge-Jensen B]]
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[[Category: Dodson, G G.]]
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[[Category: Lawson D]]
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[[Category: Huge-Jensen, B.]]
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[[Category: Patkar SR]]
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[[Category: Lawson, D.]]
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[[Category: Thim L]]
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[[Category: Patkar, S R.]]
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[[Category: Turkenburg JP]]
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[[Category: Thim, L.]]
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[[Category: Turkenburg, J P.]]
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''Page seeded by [http://oca.weizmann.ac.il/oca OCA ] on Thu Jul 3 14:11:29 2008''
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Current revision

A MODEL FOR INTERFACIAL ACTIVATION IN LIPASES FROM THE STRUCTURE OF A FUNGAL LIPASE-INHIBITOR COMPLEX

PDB ID 5tgl

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