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2pnf

From Proteopedia

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{{Seed}}
 
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[[Image:2pnf.png|left|200px]]
 
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==Structure of Aquifex Aeolicus FabG 3-oxoacyl-(acyl-carrier protein) reductase==
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The line below this paragraph, containing "STRUCTURE_2pnf", creates the "Structure Box" on the page.
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<StructureSection load='2pnf' size='340' side='right'caption='[[2pnf]], [[Resolution|resolution]] 1.80&Aring;' scene=''>
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You may change the PDB parameter (which sets the PDB file loaded into the applet)
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== Structural highlights ==
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or the SCENE parameter (which sets the initial scene displayed when the page is loaded),
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<table><tr><td colspan='2'>[[2pnf]] is a 2 chain structure with sequence from [https://en.wikipedia.org/wiki/Aquifex_aeolicus_VF5 Aquifex aeolicus VF5]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=2PNF OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=2PNF FirstGlance]. <br>
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or leave the SCENE parameter empty for the default display.
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</td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models|Method:]]</b></td><td class="sblockDat" id="methodDat">X-ray diffraction, [[Resolution|Resolution]] 1.8&#8491;</td></tr>
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<tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=1PE:PENTAETHYLENE+GLYCOL'>1PE</scene>, <scene name='pdbligand=MES:2-(N-MORPHOLINO)-ETHANESULFONIC+ACID'>MES</scene></td></tr>
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{{STRUCTURE_2pnf| PDB=2pnf | SCENE= }}
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<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=2pnf FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=2pnf OCA], [https://pdbe.org/2pnf PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=2pnf RCSB], [https://www.ebi.ac.uk/pdbsum/2pnf PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=2pnf ProSAT]</span></td></tr>
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</table>
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== Function ==
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[https://www.uniprot.org/uniprot/FABG_AQUAE FABG_AQUAE] Catalyzes the NADPH-dependent reduction of beta-ketoacyl-ACP substrates to beta-hydroxyacyl-ACP products, the first reductive step in the elongation cycle of fatty acid biosynthesis (By similarity).
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== Evolutionary Conservation ==
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[[Image:Consurf_key_small.gif|200px|right]]
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Check<jmol>
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<jmolCheckbox>
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<scriptWhenChecked>; select protein; define ~consurf_to_do selected; consurf_initial_scene = true; script "/wiki/ConSurf/pn/2pnf_consurf.spt"</scriptWhenChecked>
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<scriptWhenUnchecked>script /wiki/extensions/Proteopedia/spt/initialview01.spt</scriptWhenUnchecked>
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<text>to colour the structure by Evolutionary Conservation</text>
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</jmolCheckbox>
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</jmol>, as determined by [http://consurfdb.tau.ac.il/ ConSurfDB]. You may read the [[Conservation%2C_Evolutionary|explanation]] of the method and the full data available from [http://bental.tau.ac.il/new_ConSurfDB/main_output.php?pdb_ID=2pnf ConSurf].
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<div style="clear:both"></div>
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===Structure of Aquifex Aeolicus FabG 3-oxoacyl-(acyl-carrier protein) reductase===
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==See Also==
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*[[Beta-ketoacyl carrier protein reductase 3D structures|Beta-ketoacyl carrier protein reductase 3D structures]]
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__TOC__
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</StructureSection>
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The line below this paragraph, {{ABSTRACT_PUBMED_17277451}}, adds the Publication Abstract to the page
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[[Category: Aquifex aeolicus VF5]]
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(as it appears on PubMed at http://www.pubmed.gov), where 17277451 is the PubMed ID number.
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[[Category: Large Structures]]
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[[Category: Mao Q]]
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{{ABSTRACT_PUBMED_17277451}}
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[[Category: Umland TC]]
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==About this Structure==
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2PNF is a [[Single protein]] structure of sequence from [http://en.wikipedia.org/wiki/Aquifex_aeolicus Aquifex aeolicus]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=2PNF OCA].
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==Reference==
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Crystallization and X-ray diffraction analysis of the beta-ketoacyl-acyl carrier protein reductase FabG from Aquifex aeolicus VF5., Mao Q, Duax WL, Umland TC, Acta Crystallogr Sect F Struct Biol Cryst Commun. 2007 Feb 1;63(Pt, 2):106-9. Epub 2007 Jan 17. PMID:[http://www.ncbi.nlm.nih.gov/pubmed/17277451 17277451]
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[[Category: Aquifex aeolicus]]
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[[Category: Single protein]]
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[[Category: Mao, Q.]]
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[[Category: Umland, T C.]]
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[[Category: Rossmann fold]]
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[[Category: Short chain oxidoreductase]]
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''Page seeded by [http://oca.weizmann.ac.il/oca OCA ] on Sat Jul 5 16:25:11 2008''
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Current revision

Structure of Aquifex Aeolicus FabG 3-oxoacyl-(acyl-carrier protein) reductase

PDB ID 2pnf

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