2jsm

From Proteopedia

(Difference between revisions)
Jump to: navigation, search
Current revision (12:48, 20 December 2023) (edit) (undo)
 
(9 intermediate revisions not shown.)
Line 1: Line 1:
-
{{Seed}}
 
-
[[Image:2jsm.jpg|left|200px]]
 
-
<!--
+
==MONOMERIC HUMAN TELOMERE DNA TETRAPLEX WITH 3+1 STRAND FOLD TOPOLOGY, TWO EDGEWISE LOOPS AND DOUBLE-CHAIN REVERSAL LOOP, NMR, 10 STRUCTURES, Form 1 Natural==
-
The line below this paragraph, containing "STRUCTURE_2jsm", creates the "Structure Box" on the page.
+
<StructureSection load='2jsm' size='340' side='right'caption='[[2jsm]]' scene=''>
-
You may change the PDB parameter (which sets the PDB file loaded into the applet)
+
== Structural highlights ==
-
or the SCENE parameter (which sets the initial scene displayed when the page is loaded),
+
<table><tr><td colspan='2'>[[2jsm]] is a 1 chain structure. Full experimental information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=2JSM OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=2JSM FirstGlance]. <br>
-
or leave the SCENE parameter empty for the default display.
+
</td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models|Method:]]</b></td><td class="sblockDat" id="methodDat">Solution NMR</td></tr>
-
-->
+
<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=2jsm FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=2jsm OCA], [https://pdbe.org/2jsm PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=2jsm RCSB], [https://www.ebi.ac.uk/pdbsum/2jsm PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=2jsm ProSAT]</span></td></tr>
-
{{STRUCTURE_2jsm| PDB=2jsm | SCENE= }}
+
</table>
 +
<div style="background-color:#fffaf0;">
 +
== Publication Abstract from PubMed ==
 +
Intramolecular G-quadruplexes formed by human telomere sequences are attractive anticancer targets. Recently, four-repeat human telomere sequences have been shown to form two different intramolecular (3 + 1) G-quadruplexes in K(+) solution (Form 1 and Form 2). Here we report on the solution structures of both Form 1 and Form 2 adopted by natural human telomere sequences. Both structures contain the (3 + 1) G-tetrad core with one double-chain-reversal and two edgewise loops, but differ in the successive order of loop arrangements within the G-quadruplex scaffold. Our results provide the structural details at the two ends of the G-tetrad core in the context of natural sequences and information on different loop conformations. This structural information might be important for our understanding of telomere G-quadruplex structures and for anticancer drug design targeted to such scaffolds.
-
===MONOMERIC HUMAN TELOMERE DNA TETRAPLEX WITH 3+1 STRAND FOLD TOPOLOGY, TWO EDGEWISE LOOPS AND DOUBLE-CHAIN REVERSAL LOOP, NMR, 10 STRUCTURES, Form 1 Natural===
+
Structure of two intramolecular G-quadruplexes formed by natural human telomere sequences in K+ solution.,Phan AT, Kuryavyi V, Luu KN, Patel DJ Nucleic Acids Res. 2007;35(19):6517-25. Epub 2007 Sep 25. PMID:17895279<ref>PMID:17895279</ref>
-
 
+
From MEDLINE&reg;/PubMed&reg;, a database of the U.S. National Library of Medicine.<br>
-
<!--
+
</div>
-
The line below this paragraph, {{ABSTRACT_PUBMED_17895279}}, adds the Publication Abstract to the page
+
<div class="pdbe-citations 2jsm" style="background-color:#fffaf0;"></div>
-
(as it appears on PubMed at http://www.pubmed.gov), where 17895279 is the PubMed ID number.
+
== References ==
-
-->
+
<references/>
-
{{ABSTRACT_PUBMED_17895279}}
+
__TOC__
-
 
+
</StructureSection>
-
==About this Structure==
+
[[Category: Large Structures]]
-
Full experimental information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=2JSM OCA].
+
[[Category: Kuryavyi VV]]
-
 
+
[[Category: Luu KN]]
-
==Reference==
+
[[Category: Patel DJ]]
-
Structure of two intramolecular G-quadruplexes formed by natural human telomere sequences in K+ solution., Phan AT, Kuryavyi V, Luu KN, Patel DJ, Nucleic Acids Res. 2007;35(19):6517-25. Epub 2007 Sep 25. PMID:[http://www.ncbi.nlm.nih.gov/pubmed/17895279 17895279]
+
[[Category: Phan AT]]
-
[[Category: Kuryavyi, V V.]]
+
-
[[Category: Luu, K N.]]
+
-
[[Category: Patel, D J.]]
+
-
[[Category: Phan, A T.]]
+
-
[[Category: 10 structure]]
+
-
[[Category: 3+1 strand folding]]
+
-
[[Category: Dna]]
+
-
[[Category: Double-chain reversal loop]]
+
-
[[Category: Edgewise]]
+
-
[[Category: G-tetrad]]
+
-
[[Category: Natural form 1]]
+
-
[[Category: Nmr]]
+
-
 
+
-
''Page seeded by [http://oca.weizmann.ac.il/oca OCA ] on Wed Jul 9 10:34:15 2008''
+

Current revision

MONOMERIC HUMAN TELOMERE DNA TETRAPLEX WITH 3+1 STRAND FOLD TOPOLOGY, TWO EDGEWISE LOOPS AND DOUBLE-CHAIN REVERSAL LOOP, NMR, 10 STRUCTURES, Form 1 Natural

PDB ID 2jsm

Drag the structure with the mouse to rotate

Proteopedia Page Contributors and Editors (what is this?)

OCA

Retrieved from "http://52.214.119.220/wiki/index.php/2jsm"
Personal tools