1j8a

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(New page: 200px<br /><applet load="1j8a" size="450" color="white" frame="true" align="right" spinBox="true" caption="1j8a, resolution 1.21&Aring;" /> '''CRYSTAL STRUCTURE OF...)
Current revision (04:37, 17 October 2024) (edit) (undo)
 
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[[Image:1j8a.gif|left|200px]]<br /><applet load="1j8a" size="450" color="white" frame="true" align="right" spinBox="true"
 
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caption="1j8a, resolution 1.21&Aring;" />
 
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'''CRYSTAL STRUCTURE OF BENZAMIDINE INHIBITED BOVINE PANCREATIC TRYPSIN AT 105K TO 1.21A RESOLUTION FROM LABORATORY SOURCE WITH HIGH NUMBER OF WATERS MODELLED'''<br />
 
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==About this Structure==
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==CRYSTAL STRUCTURE OF BENZAMIDINE INHIBITED BOVINE PANCREATIC TRYPSIN AT 105K TO 1.21A RESOLUTION FROM LABORATORY SOURCE WITH HIGH NUMBER OF WATERS MODELLED==
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1J8A is a [http://en.wikipedia.org/wiki/Single_protein Single protein] structure of sequence from [http://en.wikipedia.org/wiki/Bos_taurus Bos taurus] with CA, SO4, BEN, TRS and GOL as [http://en.wikipedia.org/wiki/ligands ligands]. Active as [http://en.wikipedia.org/wiki/Trypsin Trypsin], with EC number [http://www.brenda-enzymes.info/php/result_flat.php4?ecno=3.4.21.4 3.4.21.4] Full crystallographic information is available from [http://ispc.weizmann.ac.il/oca-bin/ocashort?id=1J8A OCA].
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<StructureSection load='1j8a' size='340' side='right'caption='[[1j8a]], [[Resolution|resolution]] 1.21&Aring;' scene=''>
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[[Category: Bos taurus]]
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== Structural highlights ==
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[[Category: Single protein]]
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<table><tr><td colspan='2'>[[1j8a]] is a 1 chain structure with sequence from [https://en.wikipedia.org/wiki/Bos_taurus Bos taurus]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=1J8A OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=1J8A FirstGlance]. <br>
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[[Category: Trypsin]]
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</td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models|Method:]]</b></td><td class="sblockDat" id="methodDat">X-ray diffraction, [[Resolution|Resolution]] 1.21&#8491;</td></tr>
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[[Category: Cuesta-Seijo, J.A.]]
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<tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=BEN:BENZAMIDINE'>BEN</scene>, <scene name='pdbligand=CA:CALCIUM+ION'>CA</scene>, <scene name='pdbligand=GOL:GLYCEROL'>GOL</scene>, <scene name='pdbligand=SO4:SULFATE+ION'>SO4</scene>, <scene name='pdbligand=TRS:2-AMINO-2-HYDROXYMETHYL-PROPANE-1,3-DIOL'>TRS</scene></td></tr>
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[[Category: Garcia-Granda, S.]]
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<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=1j8a FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=1j8a OCA], [https://pdbe.org/1j8a PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=1j8a RCSB], [https://www.ebi.ac.uk/pdbsum/1j8a PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=1j8a ProSAT]</span></td></tr>
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[[Category: BEN]]
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</table>
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[[Category: CA]]
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== Function ==
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[[Category: GOL]]
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[https://www.uniprot.org/uniprot/TRY1_BOVIN TRY1_BOVIN]
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[[Category: SO4]]
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== Evolutionary Conservation ==
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[[Category: TRS]]
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[[Image:Consurf_key_small.gif|200px|right]]
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[[Category: atomic resolution]]
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Check<jmol>
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[[Category: high number of waters]]
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<jmolCheckbox>
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[[Category: protein-inhibitor complex]]
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<scriptWhenChecked>; select protein; define ~consurf_to_do selected; consurf_initial_scene = true; script "/wiki/ConSurf/j8/1j8a_consurf.spt"</scriptWhenChecked>
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<scriptWhenUnchecked>script /wiki/extensions/Proteopedia/spt/initialview03.spt</scriptWhenUnchecked>
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<text>to colour the structure by Evolutionary Conservation</text>
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</jmolCheckbox>
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</jmol>, as determined by [http://consurfdb.tau.ac.il/ ConSurfDB]. You may read the [[Conservation%2C_Evolutionary|explanation]] of the method and the full data available from [http://bental.tau.ac.il/new_ConSurfDB/main_output.php?pdb_ID=1j8a ConSurf].
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<div style="clear:both"></div>
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''Page seeded by [http://ispc.weizmann.ac.il/oca OCA ] on Tue Nov 20 18:00:26 2007''
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==See Also==
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*[[Trypsin 3D structures|Trypsin 3D structures]]
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__TOC__
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</StructureSection>
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[[Category: Bos taurus]]
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[[Category: Large Structures]]
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[[Category: Cuesta-Seijo JA]]
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[[Category: Garcia-Granda S]]

Current revision

CRYSTAL STRUCTURE OF BENZAMIDINE INHIBITED BOVINE PANCREATIC TRYPSIN AT 105K TO 1.21A RESOLUTION FROM LABORATORY SOURCE WITH HIGH NUMBER OF WATERS MODELLED

PDB ID 1j8a

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