2vsw
From Proteopedia
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| - | '''Unreleased structure''' | ||
| - | The | + | ==The structure of the rhodanese domain of the human dual specificity phosphatase 16== |
| + | <StructureSection load='2vsw' size='340' side='right'caption='[[2vsw]], [[Resolution|resolution]] 2.20Å' scene=''> | ||
| + | == Structural highlights == | ||
| + | <table><tr><td colspan='2'>[[2vsw]] is a 2 chain structure with sequence from [https://en.wikipedia.org/wiki/Homo_sapiens Homo sapiens]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=2VSW OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=2VSW FirstGlance]. <br> | ||
| + | </td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models|Method:]]</b></td><td class="sblockDat" id="methodDat">X-ray diffraction, [[Resolution|Resolution]] 2.2Å</td></tr> | ||
| + | <tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=2vsw FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=2vsw OCA], [https://pdbe.org/2vsw PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=2vsw RCSB], [https://www.ebi.ac.uk/pdbsum/2vsw PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=2vsw ProSAT]</span></td></tr> | ||
| + | </table> | ||
| + | == Function == | ||
| + | [https://www.uniprot.org/uniprot/DUS16_HUMAN DUS16_HUMAN] Dual specificity protein phosphatase involved in the inactivation of MAP kinases. Dephosphorylates MAPK10 bound to ARRB2.<ref>PMID:11489891</ref> <ref>PMID:15888437</ref> | ||
| + | == Evolutionary Conservation == | ||
| + | [[Image:Consurf_key_small.gif|200px|right]] | ||
| + | Check<jmol> | ||
| + | <jmolCheckbox> | ||
| + | <scriptWhenChecked>; select protein; define ~consurf_to_do selected; consurf_initial_scene = true; script "/wiki/ConSurf/vs/2vsw_consurf.spt"</scriptWhenChecked> | ||
| + | <scriptWhenUnchecked>script /wiki/extensions/Proteopedia/spt/initialview01.spt</scriptWhenUnchecked> | ||
| + | <text>to colour the structure by Evolutionary Conservation</text> | ||
| + | </jmolCheckbox> | ||
| + | </jmol>, as determined by [http://consurfdb.tau.ac.il/ ConSurfDB]. You may read the [[Conservation%2C_Evolutionary|explanation]] of the method and the full data available from [http://bental.tau.ac.il/new_ConSurfDB/main_output.php?pdb_ID=2vsw ConSurf]. | ||
| + | <div style="clear:both"></div> | ||
| - | + | ==See Also== | |
| - | + | *[[Dual specificity phosphatase 3D structures|Dual specificity phosphatase 3D structures]] | |
| - | + | *[[MAP kinase phosphatase|MAP kinase phosphatase]] | |
| - | + | == References == | |
| - | + | <references/> | |
| + | __TOC__ | ||
| + | </StructureSection> | ||
| + | [[Category: Homo sapiens]] | ||
| + | [[Category: Large Structures]] | ||
| + | [[Category: Arrowsmith CH]] | ||
| + | [[Category: Barr A]] | ||
| + | [[Category: Bishop S]] | ||
| + | [[Category: Bountra C]] | ||
| + | [[Category: Bray J]] | ||
| + | [[Category: Burgess-Brown N]] | ||
| + | [[Category: Edwards AM]] | ||
| + | [[Category: Elkins J]] | ||
| + | [[Category: Gileadi O]] | ||
| + | [[Category: Knapp S]] | ||
| + | [[Category: Murray JW]] | ||
| + | [[Category: Pantic N]] | ||
| + | [[Category: Phillips C]] | ||
| + | [[Category: Pike ACW]] | ||
| + | [[Category: Roos A]] | ||
| + | [[Category: Savitsky P]] | ||
| + | [[Category: Wang J]] | ||
| + | [[Category: Wickstroem M]] | ||
| + | [[Category: Von Delft F]] | ||
Current revision
The structure of the rhodanese domain of the human dual specificity phosphatase 16
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Categories: Homo sapiens | Large Structures | Arrowsmith CH | Barr A | Bishop S | Bountra C | Bray J | Burgess-Brown N | Edwards AM | Elkins J | Gileadi O | Knapp S | Murray JW | Pantic N | Phillips C | Pike ACW | Roos A | Savitsky P | Wang J | Wickstroem M | Von Delft F
