This old version of Proteopedia is provided for student assignments while the new version is undergoing repairs. Content and edits done in this old version of Proteopedia after March 1, 2026 will eventually be lost when it is retired in about June of 2026.
Apply for new accounts at the new Proteopedia. Your logins will work in both the old and new versions.
3db5
From Proteopedia
(Difference between revisions)
(New page: '''Unreleased structure''' The entry 3db5 is ON HOLD until May 30 2010 Authors: Amaya, M.F., Zeng, H., Loppnau, P., Bountra, C., Weigelt, J., Arrowsmith, C.H., Edwards, A.M., Bochkarev,...) |
|||
| (7 intermediate revisions not shown.) | |||
| Line 1: | Line 1: | ||
| - | '''Unreleased structure''' | ||
| - | + | ==Crystal structure of methyltransferase domain of human PR domain-containing protein 4== | |
| - | + | <StructureSection load='3db5' size='340' side='right'caption='[[3db5]], [[Resolution|resolution]] 2.15Å' scene=''> | |
| - | + | == Structural highlights == | |
| - | + | <table><tr><td colspan='2'>[[3db5]] is a 2 chain structure with sequence from [https://en.wikipedia.org/wiki/Human Human]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=3DB5 OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=3DB5 FirstGlance]. <br> | |
| - | + | </td></tr><tr id='NonStdRes'><td class="sblockLbl"><b>[[Non-Standard_Residue|NonStd Res:]]</b></td><td class="sblockDat"><scene name='pdbligand=MSE:SELENOMETHIONINE'>MSE</scene></td></tr> | |
| - | + | <tr id='gene'><td class="sblockLbl"><b>[[Gene|Gene:]]</b></td><td class="sblockDat">PRDM4, PFM1 ([https://www.ncbi.nlm.nih.gov/Taxonomy/Browser/wwwtax.cgi?mode=Info&srchmode=5&id=9606 HUMAN])</td></tr> | |
| - | + | <tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=3db5 FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=3db5 OCA], [https://pdbe.org/3db5 PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=3db5 RCSB], [https://www.ebi.ac.uk/pdbsum/3db5 PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=3db5 ProSAT]</span></td></tr> | |
| + | </table> | ||
| + | == Function == | ||
| + | [[https://www.uniprot.org/uniprot/PRDM4_HUMAN PRDM4_HUMAN]] May function as a transcription factor involved in cell differentiation. | ||
| + | == Evolutionary Conservation == | ||
| + | [[Image:Consurf_key_small.gif|200px|right]] | ||
| + | Check<jmol> | ||
| + | <jmolCheckbox> | ||
| + | <scriptWhenChecked>; select protein; define ~consurf_to_do selected; consurf_initial_scene = true; script "/wiki/ConSurf/db/3db5_consurf.spt"</scriptWhenChecked> | ||
| + | <scriptWhenUnchecked>script /wiki/extensions/Proteopedia/spt/initialview01.spt</scriptWhenUnchecked> | ||
| + | <text>to colour the structure by Evolutionary Conservation</text> | ||
| + | </jmolCheckbox> | ||
| + | </jmol>, as determined by [http://consurfdb.tau.ac.il/ ConSurfDB]. You may read the [[Conservation%2C_Evolutionary|explanation]] of the method and the full data available from [http://bental.tau.ac.il/new_ConSurfDB/main_output.php?pdb_ID=3db5 ConSurf]. | ||
| + | <div style="clear:both"></div> | ||
| + | __TOC__ | ||
| + | </StructureSection> | ||
| + | [[Category: Human]] | ||
| + | [[Category: Large Structures]] | ||
| + | [[Category: Amaya, M F]] | ||
| + | [[Category: Arrowsmith, C H]] | ||
| + | [[Category: Bochkarev, A]] | ||
| + | [[Category: Bountra, C]] | ||
| + | [[Category: Edwards, A M]] | ||
| + | [[Category: Loppnau, P]] | ||
| + | [[Category: Min, J]] | ||
| + | [[Category: Plotnikov, A N]] | ||
| + | [[Category: Structural genomic]] | ||
| + | [[Category: Weigelt, J]] | ||
| + | [[Category: Wu, H]] | ||
| + | [[Category: Zeng, H]] | ||
| + | [[Category: Dna-binding]] | ||
| + | [[Category: Metal-binding]] | ||
| + | [[Category: Methyltransferase]] | ||
| + | [[Category: Nucleus]] | ||
| + | [[Category: Prdm4]] | ||
| + | [[Category: Sgc]] | ||
| + | [[Category: Transcription]] | ||
| + | [[Category: Transcription regulation]] | ||
| + | [[Category: Transferase]] | ||
| + | [[Category: Zinc-finger]] | ||
Current revision
Crystal structure of methyltransferase domain of human PR domain-containing protein 4
| |||||||||||
Categories: Human | Large Structures | Amaya, M F | Arrowsmith, C H | Bochkarev, A | Bountra, C | Edwards, A M | Loppnau, P | Min, J | Plotnikov, A N | Structural genomic | Weigelt, J | Wu, H | Zeng, H | Dna-binding | Metal-binding | Methyltransferase | Nucleus | Prdm4 | Sgc | Transcription | Transcription regulation | Transferase | Zinc-finger

