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3dbo

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{{Seed}}
 
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[[Image:3dbo.jpg|left|200px]]
 
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==Crystal structure of a member of the VapBC family of toxin-antitoxin systems, VapBC-5, from Mycobacterium tuberculosis==
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The line below this paragraph, containing "STRUCTURE_3dbo", creates the "Structure Box" on the page.
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<StructureSection load='3dbo' size='340' side='right'caption='[[3dbo]], [[Resolution|resolution]] 1.76&Aring;' scene=''>
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You may change the PDB parameter (which sets the PDB file loaded into the applet)
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== Structural highlights ==
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or the SCENE parameter (which sets the initial scene displayed when the page is loaded),
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<table><tr><td colspan='2'>[[3dbo]] is a 2 chain structure with sequence from [https://en.wikipedia.org/wiki/Mycobacterium_tuberculosis_H37Rv Mycobacterium tuberculosis H37Rv]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=3DBO OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=3DBO FirstGlance]. <br>
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or leave the SCENE parameter empty for the default display.
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</td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models|Method:]]</b></td><td class="sblockDat" id="methodDat">X-ray diffraction, [[Resolution|Resolution]] 1.76&#8491;</td></tr>
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<tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=ACT:ACETATE+ION'>ACT</scene>, <scene name='pdbligand=BME:BETA-MERCAPTOETHANOL'>BME</scene>, <scene name='pdbligand=NA:SODIUM+ION'>NA</scene></td></tr>
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{{STRUCTURE_3dbo| PDB=3dbo | SCENE= }}
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<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=3dbo FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=3dbo OCA], [https://pdbe.org/3dbo PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=3dbo RCSB], [https://www.ebi.ac.uk/pdbsum/3dbo PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=3dbo ProSAT], [https://www.topsan.org/Proteins/ISFI/3dbo TOPSAN]</span></td></tr>
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</table>
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===Crystal structure of a member of the VapBC family of toxin-antitoxin systems, VapBC-5, from Mycobacterium tuberculosis===
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== Function ==
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[https://www.uniprot.org/uniprot/VAPB5_MYCTU VAPB5_MYCTU] Probable antitoxin component of a type II toxin-antitoxin (TA) system. The cognate toxin is VapC5.<ref>PMID:18952600</ref>
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== Evolutionary Conservation ==
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==About this Structure==
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[[Image:Consurf_key_small.gif|200px|right]]
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3DBO is a [[Protein complex]] structure of sequences from [http://en.wikipedia.org/wiki/Mycobacterium_tuberculosis_h37rv Mycobacterium tuberculosis h37rv]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=3DBO OCA].
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Check<jmol>
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[[Category: Mycobacterium tuberculosis h37rv]]
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<jmolCheckbox>
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[[Category: Protein complex]]
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<scriptWhenChecked>; select protein; define ~consurf_to_do selected; consurf_initial_scene = true; script "/wiki/ConSurf/db/3dbo_consurf.spt"</scriptWhenChecked>
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[[Category: Cascio, D.]]
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<scriptWhenUnchecked>script /wiki/extensions/Proteopedia/spt/initialview01.spt</scriptWhenUnchecked>
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[[Category: Eisenberg, D.]]
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<text>to colour the structure by Evolutionary Conservation</text>
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[[Category: ISFI, Integrated Center for Structure and Function Innovation.]]
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</jmolCheckbox>
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[[Category: Miallau, L.]]
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</jmol>, as determined by [http://consurfdb.tau.ac.il/ ConSurfDB]. You may read the [[Conservation%2C_Evolutionary|explanation]] of the method and the full data available from [http://bental.tau.ac.il/new_ConSurfDB/main_output.php?pdb_ID=3dbo ConSurf].
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[[Category: TBSGC, TB Structural Genomics Consortium.]]
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<div style="clear:both"></div>
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[[Category: Integrated center for structure and function innovation]]
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== References ==
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[[Category: Isfi]]
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<references/>
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[[Category: Mycobacterium tuberculosis]]
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__TOC__
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[[Category: Protein structure initiative]]
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</StructureSection>
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[[Category: Psi-2]]
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[[Category: Large Structures]]
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[[Category: Structural genomic]]
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[[Category: Mycobacterium tuberculosis H37Rv]]
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[[Category: Tb structural genomics consortium]]
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[[Category: Cascio D]]
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[[Category: Tbsgc]]
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[[Category: Eisenberg D]]
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[[Category: Toxin antitoxin complex]]
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[[Category: Miallau L]]
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[[Category: Toxin/antitoxin complex]]
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[[Category: Vapbc]]
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''Page seeded by [http://oca.weizmann.ac.il/oca OCA ] on Wed Jul 16 10:51:45 2008''
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Current revision

Crystal structure of a member of the VapBC family of toxin-antitoxin systems, VapBC-5, from Mycobacterium tuberculosis

PDB ID 3dbo

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