This old version of Proteopedia is provided for student assignments while the new version is undergoing repairs. Content and edits done in this old version of Proteopedia after March 1, 2026 will eventually be lost when it is retired in about June of 2026.

Apply for new accounts at the new Proteopedia. Your logins will work in both the old and new versions.


3dcy

From Proteopedia

(Difference between revisions)
Jump to: navigation, search
Current revision (08:01, 2 February 2022) (edit) (undo)
 
(6 intermediate revisions not shown.)
Line 1: Line 1:
-
{{Seed}}
 
-
[[Image:3dcy.jpg|left|200px]]
 
-
<!--
+
==Crystal Structure a TP53-induced glycolysis and apoptosis regulator protein from Homo sapiens.==
-
The line below this paragraph, containing "STRUCTURE_3dcy", creates the "Structure Box" on the page.
+
<StructureSection load='3dcy' size='340' side='right'caption='[[3dcy]], [[Resolution|resolution]] 1.75&Aring;' scene=''>
-
You may change the PDB parameter (which sets the PDB file loaded into the applet)
+
== Structural highlights ==
-
or the SCENE parameter (which sets the initial scene displayed when the page is loaded),
+
<table><tr><td colspan='2'>[[3dcy]] is a 1 chain structure with sequence from [https://en.wikipedia.org/wiki/Human Human]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=3DCY OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=3DCY FirstGlance]. <br>
-
or leave the SCENE parameter empty for the default display.
+
</td></tr><tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=PO4:PHOSPHATE+ION'>PO4</scene></td></tr>
-
-->
+
<tr id='NonStdRes'><td class="sblockLbl"><b>[[Non-Standard_Residue|NonStd Res:]]</b></td><td class="sblockDat"><scene name='pdbligand=MSE:SELENOMETHIONINE'>MSE</scene></td></tr>
-
{{STRUCTURE_3dcy| PDB=3dcy | SCENE= }}
+
<tr id='gene'><td class="sblockLbl"><b>[[Gene|Gene:]]</b></td><td class="sblockDat">C12orf5 ([https://www.ncbi.nlm.nih.gov/Taxonomy/Browser/wwwtax.cgi?mode=Info&srchmode=5&id=9606 HUMAN])</td></tr>
-
 
+
<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=3dcy FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=3dcy OCA], [https://pdbe.org/3dcy PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=3dcy RCSB], [https://www.ebi.ac.uk/pdbsum/3dcy PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=3dcy ProSAT], [https://www.topsan.org/Proteins/CESG/3dcy TOPSAN]</span></td></tr>
-
===Crystal Structure a TP53-induced glycolysis and apoptosis regulator protein from Homo sapiens.===
+
</table>
-
 
+
== Function ==
-
 
+
[[https://www.uniprot.org/uniprot/TIGAR_HUMAN TIGAR_HUMAN]] Fructose-bisphosphatase hydrolyzing fructose-2,6-bisphosphate as well as fructose-1,6-bisphosphate. Inhibits glycolysis by reducing cellular levels of fructose-2,6-bisphosphate. May protect cells against reactive oxygen species and against apoptosis induced by tp53.<ref>PMID:16839880</ref>
-
==About this Structure==
+
== Evolutionary Conservation ==
-
3DCY is a [[Single protein]] structure of sequence from [http://en.wikipedia.org/wiki/Homo_sapiens Homo sapiens]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=3DCY OCA].
+
[[Image:Consurf_key_small.gif|200px|right]]
-
[[Category: Homo sapiens]]
+
Check<jmol>
-
[[Category: Single protein]]
+
<jmolCheckbox>
-
[[Category: Bingman, C A.]]
+
<scriptWhenChecked>; select protein; define ~consurf_to_do selected; consurf_initial_scene = true; script "/wiki/ConSurf/dc/3dcy_consurf.spt"</scriptWhenChecked>
-
[[Category: CESG, Center for Eukaryotic Structural Genomics.]]
+
<scriptWhenUnchecked>script /wiki/extensions/Proteopedia/spt/initialview01.spt</scriptWhenUnchecked>
-
[[Category: Jr., G N.Phillips.]]
+
<text>to colour the structure by Evolutionary Conservation</text>
-
[[Category: McCoy, J G.]]
+
</jmolCheckbox>
-
[[Category: Wesenberg, G E.]]
+
</jmol>, as determined by [http://consurfdb.tau.ac.il/ ConSurfDB]. You may read the [[Conservation%2C_Evolutionary|explanation]] of the method and the full data available from [http://bental.tau.ac.il/new_ConSurfDB/main_output.php?pdb_ID=3dcy ConSurf].
 +
<div style="clear:both"></div>
 +
== References ==
 +
<references/>
 +
__TOC__
 +
</StructureSection>
 +
[[Category: Human]]
 +
[[Category: Large Structures]]
 +
[[Category: Bingman, C A]]
 +
[[Category: Structural genomic]]
 +
[[Category: McCoy, J G]]
 +
[[Category: Phillips, G N]]
 +
[[Category: Wesenberg, G E]]
 +
[[Category: Apoptosis regulator]]
[[Category: C12orf5]]
[[Category: C12orf5]]
[[Category: Casp target]]
[[Category: Casp target]]
-
[[Category: Center for eukaryotic structural genomic]]
 
[[Category: Cesg]]
[[Category: Cesg]]
[[Category: Isomerase]]
[[Category: Isomerase]]
[[Category: Omim 610775]]
[[Category: Omim 610775]]
[[Category: Phosphoprotein]]
[[Category: Phosphoprotein]]
-
[[Category: Protein structure initiative]]
+
[[Category: PSI, Protein structure initiative]]
-
[[Category: Psi]]
+
-
[[Category: Structural genomics medical relevance]]
+
[[Category: Tigar]]
[[Category: Tigar]]
[[Category: Tp53-induced glycolysis and apoptosis regulator]]
[[Category: Tp53-induced glycolysis and apoptosis regulator]]
- 
-
''Page seeded by [http://oca.weizmann.ac.il/oca OCA ] on Wed Jul 16 10:52:12 2008''
 

Current revision

Crystal Structure a TP53-induced glycolysis and apoptosis regulator protein from Homo sapiens.

PDB ID 3dcy

Drag the structure with the mouse to rotate

Proteopedia Page Contributors and Editors (what is this?)

OCA

Retrieved from "http://52.214.119.220/wiki/index.php/3dcy"
Personal tools