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SelB

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{{STRUCTURE_1wsu | PDB=1wsu | SCENE=Goodsell_Sandbox/1wsu-recognition0/1 }}
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<StructureSection load='1wsu' size='350' side='right' scene=''' caption='Elongation factor SelB C terminal tetramer complex with RNA [[1wsu]]'>
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'''Elongation factor SelB''' uses several methods to recognize the selenocysteine insertion sequence found in messenger RNA. The insertion sequence forms a hairpin loop with an unstacked guanine base in the loop. This guanine forms
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Elongation factor SelB uses several methods to recognize the selenocysteine insertion sequence found in messenger RNA. The insertion sequence forms a hairpin loop with an unstacked guanine base in the loop. This guanine forms
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<scene name='SelB_Recognition/1wsu-recognition1/3'>specific hydrogen bonds with the protein and with two bridging water molecules (shown in cyan in the jmol).</scene>
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<scene name='SelB_Recognition/1wsu-recognition1/1'>specific hydrogen bonds with the protein and with two bridging water molecules (shown in cyan in the jmol).</scene>
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The planar base is also sandwiched between
The planar base is also sandwiched between
<scene name='Sandbox_14/1wsu-recognition2/2'>three amino acids</scene> in the protein, which form a tight hydrophobic pocket. This is best seen using a
<scene name='Sandbox_14/1wsu-recognition2/2'>three amino acids</scene> in the protein, which form a tight hydrophobic pocket. This is best seen using a
<scene name='Sandbox_14/1wsu-recognition3/1'>spacefilling diagram.</scene>
<scene name='Sandbox_14/1wsu-recognition3/1'>spacefilling diagram.</scene>
The overall shape of the hairpin is recognized by contacts with several
The overall shape of the hairpin is recognized by contacts with several
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<scene name='Sandbox_14/1wsu-recognition4/1'>arginine and lysine amino acids.</scene>
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<scene name='SelB_Recognition/1wsu-recognition4/1'>arginine and lysine amino acids.</scene>
In particular, notice the intimate contact formed by both the charged nitrogen and hydrophobic carbon chain of
In particular, notice the intimate contact formed by both the charged nitrogen and hydrophobic carbon chain of
<scene name='Sandbox_14/1wsu-recognition5/1'>arginine 606.</scene>
<scene name='Sandbox_14/1wsu-recognition5/1'>arginine 606.</scene>
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This page complements the article on [http://www.rcsb.org/pdb/static.do?p=education_discussion/molecule_of_the_month/pdb104_1.html Selenocysteine Synthase] in the
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[http://www.rcsb.org/pdb/static.do?p=education_discussion/molecule_of_the_month/index.html Molecule of the Month] Series. See also [[Teaching Scenes, Tutorials, and Educators' Pages]].
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{{Clear}}
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</StructureSection>
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==3D structures of SelB==
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[[1lva]] – MtSelB C terminal – ''Moorella thermoacetica''<br />
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[[2v9v]] - MtSelB winged-helix domains<br />
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[[4aca]] – MmSelB – ''Methanococcus maripaludis''
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===SelB complex with nucleotides===
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[[4ac9]] – MmSelB + GDP <br />
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[[4acb]] – MmSelB + GPPNHP<br />
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[[1wsu]], [[2uwm]] - MtSelB C terminal + RNA<br />
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[[2pjp]] – EcSelB mRNA-binding domain + RNA – ''Eschrichia coli''<br />
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[[2ply]] - EcSelB mRNA-binding domain (mutant) + RNA
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==Additional Resources==
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For additional information, see: [[Translation]]
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<br />
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[[Category:Topic Page]]

Current revision

Elongation factor SelB C terminal tetramer complex with RNA 1wsu

Drag the structure with the mouse to rotate

3D structures of SelB

1lva – MtSelB C terminal – Moorella thermoacetica
2v9v - MtSelB winged-helix domains
4aca – MmSelB – Methanococcus maripaludis

SelB complex with nucleotides

4ac9 – MmSelB + GDP
4acb – MmSelB + GPPNHP
1wsu, 2uwm - MtSelB C terminal + RNA
2pjp – EcSelB mRNA-binding domain + RNA – Eschrichia coli
2ply - EcSelB mRNA-binding domain (mutant) + RNA

Additional Resources

For additional information, see: Translation

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