3bx3

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{{Seed}}
 
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[[Image:3bx3.png|left|200px]]
 
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==Puf4 T650C/C724R Mutant bound to Cox17 RNA 3' UTR recognition sequence==
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The line below this paragraph, containing "STRUCTURE_3bx3", creates the "Structure Box" on the page.
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<StructureSection load='3bx3' size='340' side='right'caption='[[3bx3]], [[Resolution|resolution]] 3.00&Aring;' scene=''>
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You may change the PDB parameter (which sets the PDB file loaded into the applet)
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== Structural highlights ==
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or the SCENE parameter (which sets the initial scene displayed when the page is loaded),
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<table><tr><td colspan='2'>[[3bx3]] is a 4 chain structure with sequence from [https://en.wikipedia.org/wiki/Saccharomyces_cerevisiae Saccharomyces cerevisiae]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=3BX3 OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=3BX3 FirstGlance]. <br>
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or leave the SCENE parameter empty for the default display.
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</td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models|Method:]]</b></td><td class="sblockDat" id="methodDat">X-ray diffraction, [[Resolution|Resolution]] 3&#8491;</td></tr>
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<tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=SO4:SULFATE+ION'>SO4</scene></td></tr>
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{{STRUCTURE_3bx3| PDB=3bx3 | SCENE= }}
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<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=3bx3 FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=3bx3 OCA], [https://pdbe.org/3bx3 PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=3bx3 RCSB], [https://www.ebi.ac.uk/pdbsum/3bx3 PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=3bx3 ProSAT]</span></td></tr>
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</table>
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===Puf4 T650C/C724R Mutant bound to Cox17 RNA 3' UTR recognition sequence===
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== Function ==
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[https://www.uniprot.org/uniprot/PUF4_YEAST PUF4_YEAST] Is not essential for haploid growth, but may affect diploid formation.
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== Evolutionary Conservation ==
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[[Image:Consurf_key_small.gif|200px|right]]
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The line below this paragraph, {{ABSTRACT_PUBMED_18327269}}, adds the Publication Abstract to the page
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Check<jmol>
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(as it appears on PubMed at http://www.pubmed.gov), where 18327269 is the PubMed ID number.
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<jmolCheckbox>
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<scriptWhenChecked>; select protein; define ~consurf_to_do selected; consurf_initial_scene = true; script "/wiki/ConSurf/bx/3bx3_consurf.spt"</scriptWhenChecked>
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{{ABSTRACT_PUBMED_18327269}}
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<scriptWhenUnchecked>script /wiki/extensions/Proteopedia/spt/initialview01.spt</scriptWhenUnchecked>
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<text>to colour the structure by Evolutionary Conservation</text>
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==About this Structure==
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</jmolCheckbox>
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3BX3 is a [[Single protein]] structure of sequence from [http://en.wikipedia.org/wiki/Saccharomyces_cerevisiae Saccharomyces cerevisiae]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=3BX3 OCA].
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</jmol>, as determined by [http://consurfdb.tau.ac.il/ ConSurfDB]. You may read the [[Conservation%2C_Evolutionary|explanation]] of the method and the full data available from [http://bental.tau.ac.il/new_ConSurfDB/main_output.php?pdb_ID=3bx3 ConSurf].
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<div style="clear:both"></div>
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==Reference==
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__TOC__
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Basis of altered RNA-binding specificity by PUF proteins revealed by crystal structures of yeast Puf4p., Miller MT, Higgin JJ, Hall TM, Nat Struct Mol Biol. 2008 Apr;15(4):397-402. Epub 2008 Mar 9. PMID:[http://www.ncbi.nlm.nih.gov/pubmed/18327269 18327269]
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</StructureSection>
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[[Category: Large Structures]]
[[Category: Saccharomyces cerevisiae]]
[[Category: Saccharomyces cerevisiae]]
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[[Category: Single protein]]
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[[Category: Hall TMT]]
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[[Category: Hall, T M.T.]]
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[[Category: Higgin JJ]]
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[[Category: Higgin, J J.]]
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[[Category: Miller MT]]
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[[Category: Miller, M T.]]
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[[Category: Ho endonuclease]]
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[[Category: Puf4]]
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[[Category: Puf4 t650c c724r mutant]]
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[[Category: Pumilio]]
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[[Category: Rna binding]]
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[[Category: Rna binding protein/rna complex]]
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[[Category: Transcription]]
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''Page seeded by [http://oca.weizmann.ac.il/oca OCA ] on Wed Jul 23 10:02:33 2008''
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Current revision

Puf4 T650C/C724R Mutant bound to Cox17 RNA 3' UTR recognition sequence

PDB ID 3bx3

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