1r5p

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{{Seed}}
 
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[[Image:1r5p.png|left|200px]]
 
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==Crystal Structure Analysis of KaiB from PCC7120==
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The line below this paragraph, containing "STRUCTURE_1r5p", creates the "Structure Box" on the page.
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<StructureSection load='1r5p' size='340' side='right'caption='[[1r5p]], [[Resolution|resolution]] 2.20&Aring;' scene=''>
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== Structural highlights ==
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or the SCENE parameter (which sets the initial scene displayed when the page is loaded),
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<table><tr><td colspan='2'>[[1r5p]] is a 2 chain structure with sequence from [https://en.wikipedia.org/wiki/Nostoc_sp._PCC_7120_=_FACHB-418 Nostoc sp. PCC 7120 = FACHB-418]. The January 2008 RCSB PDB [https://pdb.rcsb.org/pdb/static.do?p=education_discussion/molecule_of_the_month/index.html Molecule of the Month] feature on ''Circadian Clock Proteins'' by David S. Goodsell is [https://dx.doi.org/10.2210/rcsb_pdb/mom_2008_1 10.2210/rcsb_pdb/mom_2008_1]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=1R5P OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=1R5P FirstGlance]. <br>
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</td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models|Method:]]</b></td><td class="sblockDat" id="methodDat">X-ray diffraction, [[Resolution|Resolution]] 2.2&#8491;</td></tr>
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<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=1r5p FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=1r5p OCA], [https://pdbe.org/1r5p PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=1r5p RCSB], [https://www.ebi.ac.uk/pdbsum/1r5p PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=1r5p ProSAT]</span></td></tr>
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{{STRUCTURE_1r5p| PDB=1r5p | SCENE= }}
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</table>
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== Function ==
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[https://www.uniprot.org/uniprot/KAIB_NOSS1 KAIB_NOSS1] Component of the KaiABC clock protein complex, which constitutes the main circadian regulator in cyanobacteria. The KaiABC complex may act as a promoter-non-specific transcription regulator that represses transcription, possibly by acting on the state of chromosome compaction. In the complex, it decreases the phosphorylation status of KaiC. It has no effect on KaiC by itself, but instead needs the presence of both KaiA and KaiC, suggesting that it acts by antagonizing the interaction between KaiA and KaiC (By similarity).
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== Evolutionary Conservation ==
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[[Image:Consurf_key_small.gif|200px|right]]
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Check<jmol>
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<jmolCheckbox>
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<scriptWhenChecked>; select protein; define ~consurf_to_do selected; consurf_initial_scene = true; script "/wiki/ConSurf/r5/1r5p_consurf.spt"</scriptWhenChecked>
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<scriptWhenUnchecked>script /wiki/extensions/Proteopedia/spt/initialview01.spt</scriptWhenUnchecked>
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<text>to colour the structure by Evolutionary Conservation</text>
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</jmolCheckbox>
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</jmol>, as determined by [http://consurfdb.tau.ac.il/ ConSurfDB]. You may read the [[Conservation%2C_Evolutionary|explanation]] of the method and the full data available from [http://bental.tau.ac.il/new_ConSurfDB/main_output.php?pdb_ID=1r5p ConSurf].
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<div style="clear:both"></div>
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===Crystal Structure Analysis of KaiB from PCC7120===
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==See Also==
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*[[Circadian clock protein 3D structures|Circadian clock protein 3D structures]]
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__TOC__
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</StructureSection>
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(as it appears on PubMed at http://www.pubmed.gov), where 15071498 is the PubMed ID number.
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{{ABSTRACT_PUBMED_15071498}}
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==About this Structure==
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1R5P is a [[Single protein]] structure of sequence from [http://en.wikipedia.org/wiki/Anabaena_sp. Anabaena sp.]. Additional information on 1R5P is available in a page on [http://pdb.rcsb.org/pdb/static.do?p=education_discussion/molecule_of_the_month/pdb97_1.html Circadian Clock Proteins] at the RCSB PDB [http://pdb.rcsb.org/pdb/static.do?p=education_discussion/molecule_of_the_month/index.html Molecule of the Month]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=1R5P OCA].
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==Reference==
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Anabaena circadian clock proteins KaiA and KaiB reveal a potential common binding site to their partner KaiC., Garces RG, Wu N, Gillon W, Pai EF, EMBO J. 2004 Apr 21;23(8):1688-98. Epub 2004 Apr 8. PMID:[http://www.ncbi.nlm.nih.gov/pubmed/15071498 15071498]
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[[Category: Anabaena sp.]]
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[[Category: Circadian Clock Proteins]]
[[Category: Circadian Clock Proteins]]
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[[Category: Single protein]]
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[[Category: Large Structures]]
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[[Category: Garces, R G.]]
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[[Category: Nostoc sp. PCC 7120 = FACHB-418]]
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[[Category: Gillon, W.]]
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[[Category: RCSB PDB Molecule of the Month]]
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[[Category: Pai, E F.]]
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[[Category: Garces RG]]
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[[Category: Wu, N.]]
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[[Category: Gillon W]]
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[[Category: Alpha-beta meander]]
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[[Category: Pai EF]]
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[[Category: Protein dimer]]
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[[Category: Wu N]]
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''Page seeded by [http://oca.weizmann.ac.il/oca OCA ] on Wed Jul 23 10:55:30 2008''
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Current revision

Crystal Structure Analysis of KaiB from PCC7120

PDB ID 1r5p

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