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Template:STRUCTURE 3ddq

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{{Structure
{{Structure
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|PDB= {{{PDB}}}|SCENE={{{SCENE}}}|SIZE={{{SIZE|350}}}|CAPTION={{{CAPTION|3ddq, resolution 1.80&Aring; (<scene name='initialview01'>initial scene</scene>)}}}
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|PDB= {{{PDB}}}|SCENE={{{SCENE|}}}|SIZE={{{SIZE|350}}}|CAPTION={{{CAPTION|[[3ddq]], [[Resolution|resolution]] 1.80&Aring; (<scene name='initialview01'>default scene</scene>)}}}
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|SITE= <scene name='pdbsite=AC1:Rrc+Binding+Site+For+Residue+A+299'>AC1</scene>, <scene name='pdbsite=AC2:Rrc+Binding+Site+For+Residue+C+299'>AC2</scene>, <scene name='pdbsite=AC3:Sgm+Binding+Site+For+Residue+B+1'>AC3</scene>, <scene name='pdbsite=AC4:Sgm+Binding+Site+For+Residue+D+1'>AC4</scene> and <scene name='pdbsite=AC5:Sgm+Binding+Site+For+Residue+B+440'>AC5</scene>
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|LIGAND= <scene name='pdbligand=RRC:R-ROSCOVITINE'>RRC</scene>, <scene name='pdbligand=SGM:MONOTHIOGLYCEROL'>SGM</scene>
|LIGAND= <scene name='pdbligand=RRC:R-ROSCOVITINE'>RRC</scene>, <scene name='pdbligand=SGM:MONOTHIOGLYCEROL'>SGM</scene>
|ACTIVITY= <span class='plainlinks'>[http://en.wikipedia.org/wiki/Cyclin-dependent_kinase Cyclin-dependent kinase], with EC number [http://www.brenda-enzymes.info/php/result_flat.php4?ecno=2.7.11.22 2.7.11.22] </span>
|ACTIVITY= <span class='plainlinks'>[http://en.wikipedia.org/wiki/Cyclin-dependent_kinase Cyclin-dependent kinase], with EC number [http://www.brenda-enzymes.info/php/result_flat.php4?ecno=2.7.11.22 2.7.11.22] </span>
|GENE= CDK2 ([http://www.ncbi.nlm.nih.gov/Taxonomy/Browser/wwwtax.cgi?mode=Info&srchmode=5&id=9606 Homo sapiens]), CCNA2, CCNA ([http://www.ncbi.nlm.nih.gov/Taxonomy/Browser/wwwtax.cgi?mode=Info&srchmode=5&id=9913 Bos taurus])
|GENE= CDK2 ([http://www.ncbi.nlm.nih.gov/Taxonomy/Browser/wwwtax.cgi?mode=Info&srchmode=5&id=9606 Homo sapiens]), CCNA2, CCNA ([http://www.ncbi.nlm.nih.gov/Taxonomy/Browser/wwwtax.cgi?mode=Info&srchmode=5&id=9913 Bos taurus])
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|DOMAIN=<span class='plainlinks'>[http://www.ncbi.nlm.nih.gov/Structure/cdd/cddsrv.cgi?uid=cd00180 S_TKc], [http://www.ncbi.nlm.nih.gov/Structure/cdd/cddsrv.cgi?uid=smart00220 S_TKc]</span>
 
|RELATEDENTRY=[[3ddp|3ddp]]
|RELATEDENTRY=[[3ddp|3ddp]]
|NONSTDRES=<scene name='pdbligand=TPO:PHOSPHOTHREONINE'>TPO</scene>
|NONSTDRES=<scene name='pdbligand=TPO:PHOSPHOTHREONINE'>TPO</scene>
|RESOURCES=<span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=3ddq FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=3ddq OCA], [http://www.ebi.ac.uk/pdbsum/3ddq PDBsum], [http://www.rcsb.org/pdb/explore.do?structureId=3ddq RCSB]</span>
|RESOURCES=<span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=3ddq FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=3ddq OCA], [http://www.ebi.ac.uk/pdbsum/3ddq PDBsum], [http://www.rcsb.org/pdb/explore.do?structureId=3ddq RCSB]</span>
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|FUNCTION={{GO|id=GO:0016301 | text = kinase activity}}{{GO|id=GO:0035173 | text = histone kinase activity}}{{GO|id=GO:0005515 | text = protein binding}}{{GO|id=GO:0004672 | text = protein kinase activity}}{{GO|id=GO:0042802 | text = identical protein binding}}{{GO|id=GO:0005524 | text = ATP binding}}{{GO|id=GO:0016740 | text = transferase activity}}{{GO|id=GO:0000166 | text = nucleotide binding}}{{GO|id=GO:0004674 | text = protein serine/threonine kinase activity}}{{GO|id=GO:0004693 | text = cyclin-dependent protein kinase activity}}
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|PROCESS={{GO|id=GO:0000086 | text = G2/M transition of mitotic cell cycle}}{{GO|id=GO:0007089 | text = traversing start control point of mitotic cell cycle}}{{GO|id=GO:0008284 | text = positive regulation of cell proliferation}}{{GO|id=GO:0007067 | text = mitosis}}{{GO|id=GO:0006275 | text = regulation of DNA replication}}{{GO|id=GO:0007049 | text = cell cycle}}{{GO|id=GO:0006468 | text = protein amino acid phosphorylation}}{{GO|id=GO:0006260 | text = DNA replication}}{{GO|id=GO:0051301 | text = cell division}}{{GO|id=GO:0045941 | text = positive regulation of transcription}}
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|COMPONENT={{GO|id=GO:0000307 | text = cyclin-dependent protein kinase holoenzyme complex}}{{GO|id=GO:0005829 | text = cytosol}}{{GO|id=GO:0005737 | text = cytoplasm}}{{GO|id=GO:0005654 | text = nucleoplasm}}{{GO|id=GO:0005634 | text = nucleus}}{{GO|id=GO:0001939 | text = female pronucleus}}{{GO|id=GO:0001940 | text = male pronucleus}}
 +
|SARESOURCES=<span class='plainlinks'>InterPro : [http://www.ebi.ac.uk/interpro/ISearch?query=IPR000719 Ipr000719], [http://www.ebi.ac.uk/interpro/ISearch?query=IPR002290 Ipr002290], [http://www.ebi.ac.uk/interpro/ISearch?query=IPR008271 Ipr008271], [http://www.ebi.ac.uk/interpro/ISearch?query=IPR011009 Ipr011009], [http://www.ebi.ac.uk/interpro/ISearch?query=IPR017441 Ipr017441], [http://www.ebi.ac.uk/interpro/ISearch?query=IPR017442 Ipr017442], [http://www.ebi.ac.uk/interpro/ISearch?query=IPR004367 Ipr004367], [http://www.ebi.ac.uk/interpro/ISearch?query=IPR006670 Ipr006670], [http://www.ebi.ac.uk/interpro/ISearch?query=IPR006671 Ipr006671], [http://www.ebi.ac.uk/interpro/ISearch?query=IPR011028 Ipr011028], [http://www.ebi.ac.uk/interpro/ISearch?query=IPR013763 Ipr013763], [http://www.ebi.ac.uk/interpro/ISearch?query=IPR014400 Ipr014400], [http://www.ebi.ac.uk/interpro/ISearch?query=IPR015453 Ipr015453]<br>Pfam : [http://pfam.sanger.ac.uk/family?acc=PF00069 PF00069], [http://pfam.sanger.ac.uk/family?acc=PF00134 PF00134], [http://pfam.sanger.ac.uk/family?acc=PF02984 PF02984]</span>
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|uPDB=3DDQ|CONSURF={{!}}-
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{{!}} colspan="2" style="background-color:#bac9f7;color:#040d44;vertical-align:top;text-align:left;" {{!}} [[Image:Consurf_key_small.gif|center]]
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{{!}}-{{!}} style="background-color:#bac9f7;color:#040d44;vertical-align:top;text-align:left;"
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{{!}} '''Toggle Conservation Colors:'''
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{{!}} align="left" style="background-color:#acfaac;border-top:2px solid #dddddd; border-right:2px solid #dddddd" {{!}}
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Rows = identical sequences:
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<jmol>
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<jmolButton>
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<script></script>
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<text>A [x]</text>
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<name>jmb_3ddq_A</name>
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<title>toggle chain A</title>
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<jsscript>ConsurfChainButton(elementClicked)</jsscript>
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<appendtargetsuffixtoid>true</appendtargetsuffixtoid>
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</jmolButton>
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</jmol>
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<jmol>
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<jmolButton>
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<script></script>
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<text>C [x]</text>
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<name>jmb_3ddq_C</name>
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<title>toggle chain C</title>
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<jsscript>ConsurfChainButton(elementClicked)</jsscript>
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<appendtargetsuffixtoid>true</appendtargetsuffixtoid>
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</jmolButton>
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</jmol>
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 +
<jmol>
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<jmolButton>
 +
<script></script>
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<text>B [x]</text>
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<name>jmb_3ddq_B</name>
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<title>toggle chain B</title>
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<jsscript>ConsurfChainButton(elementClicked)</jsscript>
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<appendtargetsuffixtoid>true</appendtargetsuffixtoid>
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</jmolButton>
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</jmol>
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<jmol>
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<jmolButton>
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<script></script>
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<text>D [x]</text>
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<name>jmb_3ddq_D</name>
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<title>toggle chain D</title>
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<jsscript>ConsurfChainButton(elementClicked)</jsscript>
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<appendtargetsuffixtoid>true</appendtargetsuffixtoid>
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</jmolButton>
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</jmol>
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}}
}}

Current revision

Drag the structure with the mouse to rotate
3ddq, resolution 1.80Å ()
Ligands: ,
Non-Standard Residues:
Gene: CDK2 (Homo sapiens), CCNA2, CCNA (Bos taurus)
Activity: Cyclin-dependent kinase, with EC number 2.7.11.22
Related: 3ddp
Resources: FirstGlance, OCA, PDBsum, RCSB
Coordinates: save as pdb, mmCIF, xml


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