2a12
From Proteopedia
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(New page: '''Theoretical Model''' The entry 2A12 is a Theoretical Model titled 'Theoretical model of the ai5g group II intron'. Category:Theoretical Model ''Page seeded by [http://oca.weizma...) |
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| - | + | {{Theoretical_model}} | |
| - | + | ==THEORETICAL MODEL OF THE AI5G GROUP II INTRON== | |
| + | <StructureSection load='2a12' size='340' side='right'caption='[[2a12]]' scene=''> | ||
| + | == Structural highlights == | ||
| + | <table><tr><td colspan='2'>For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=2A12 FirstGlance]. <br> | ||
| + | </td></tr><tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=2a12 FirstGlance], [https://www.ebi.ac.uk/pdbsum/2a12 PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=2a12 ProSAT]</span></td></tr> | ||
| + | </table> | ||
| + | <div style="background-color:#fffaf0;"> | ||
| + | == Publication Abstract from PubMed == | ||
| + | Despite the biological importance of self-splicing group II introns, little is known about their structural organization. Synthetic incorporation of site-specific photo-cross-linkers within catalytic domains resulted in functional distance constraints that, when combined with known tertiary interactions, provide a three-dimensional view of the active intron architecture. All functionalities important for both steps of splicing are proximal before the first step, suggestive of a single active-site region for group II intron catalysis. | ||
| - | + | A single active-site region for a group II intron.,de Lencastre A, Hamill S, Pyle AM Nat Struct Mol Biol. 2005 Jul;12(7):626-7. Epub 2005 Jun 26. PMID:15980867<ref>PMID:15980867</ref> | |
| - | + | From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine.<br> | |
| - | + | </div> | |
| + | <div class="pdbe-citations 2a12" style="background-color:#fffaf0;"></div> | ||
| + | == References == | ||
| + | <references/> | ||
| + | __TOC__ | ||
| + | </StructureSection> | ||
| + | [[Category: Theoretical Model]] | ||
| + | [[Category: Large Structures]] | ||
| + | [[Category: De Lencastre, A]] | ||
| + | [[Category: Hamill, S]] | ||
| + | [[Category: Pyle, A M]] | ||
Current revision
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THEORETICAL MODEL OF THE AI5G GROUP II INTRON
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