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1qw1

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{{Seed}}
 
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[[Image:1qw1.png|left|200px]]
 
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==Solution Structure of the C-Terminal Domain of DtxR residues 110-226==
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The line below this paragraph, containing "STRUCTURE_1qw1", creates the "Structure Box" on the page.
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<StructureSection load='1qw1' size='340' side='right'caption='[[1qw1]]' scene=''>
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You may change the PDB parameter (which sets the PDB file loaded into the applet)
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== Structural highlights ==
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or the SCENE parameter (which sets the initial scene displayed when the page is loaded),
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<table><tr><td colspan='2'>[[1qw1]] is a 1 chain structure with sequence from [https://en.wikipedia.org/wiki/Corynebacterium_diphtheriae Corynebacterium diphtheriae]. Full experimental information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=1QW1 OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=1QW1 FirstGlance]. <br>
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or leave the SCENE parameter empty for the default display.
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</td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models|Method:]]</b></td><td class="sblockDat" id="methodDat">Solution NMR</td></tr>
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<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=1qw1 FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=1qw1 OCA], [https://pdbe.org/1qw1 PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=1qw1 RCSB], [https://www.ebi.ac.uk/pdbsum/1qw1 PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=1qw1 ProSAT]</span></td></tr>
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{{STRUCTURE_1qw1| PDB=1qw1 | SCENE= }}
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</table>
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== Function ==
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[https://www.uniprot.org/uniprot/DTXR_CORDI DTXR_CORDI] Iron-binding repressor of the dipheteria toxin gene expression. May serve as a global regulator of gene expression. Represses ripA under iron excess.
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== Evolutionary Conservation ==
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[[Image:Consurf_key_small.gif|200px|right]]
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Check<jmol>
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<jmolCheckbox>
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<scriptWhenChecked>; select protein; define ~consurf_to_do selected; consurf_initial_scene = true; script "/wiki/ConSurf/qw/1qw1_consurf.spt"</scriptWhenChecked>
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<scriptWhenUnchecked>script /wiki/extensions/Proteopedia/spt/initialview01.spt</scriptWhenUnchecked>
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<text>to colour the structure by Evolutionary Conservation</text>
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</jmolCheckbox>
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</jmol>, as determined by [http://consurfdb.tau.ac.il/ ConSurfDB]. You may read the [[Conservation%2C_Evolutionary|explanation]] of the method and the full data available from [http://bental.tau.ac.il/new_ConSurfDB/main_output.php?pdb_ID=1qw1 ConSurf].
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<div style="clear:both"></div>
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===Solution Structure of the C-Terminal Domain of DtxR residues 110-226===
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==See Also==
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*[[Diphtheria toxin repressor|Diphtheria toxin repressor]]
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__TOC__
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<!--
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</StructureSection>
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The line below this paragraph, {{ABSTRACT_PUBMED_15628844}}, adds the Publication Abstract to the page
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(as it appears on PubMed at http://www.pubmed.gov), where 15628844 is the PubMed ID number.
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{{ABSTRACT_PUBMED_15628844}}
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==About this Structure==
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1QW1 is a [[Single protein]] structure of sequence from [http://en.wikipedia.org/wiki/Corynebacterium_diphtheriae Corynebacterium diphtheriae]. Full experimental information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=1QW1 OCA].
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==Reference==
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Prolylpeptide binding by the prokaryotic SH3-like domain of the diphtheria toxin repressor: a regulatory switch., Wylie GP, Rangachari V, Bienkiewicz EA, Marin V, Bhattacharya N, Love JF, Murphy JR, Logan TM, Biochemistry. 2005 Jan 11;44(1):40-51. PMID:[http://www.ncbi.nlm.nih.gov/pubmed/15628844 15628844]
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[[Category: Corynebacterium diphtheriae]]
[[Category: Corynebacterium diphtheriae]]
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[[Category: Single protein]]
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[[Category: Large Structures]]
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[[Category: Bienkiewicz, E A.]]
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[[Category: Bienkiewicz EA]]
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[[Category: Logan, T M.]]
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[[Category: Logan TM]]
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[[Category: Love, J F.]]
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[[Category: Love JF]]
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[[Category: Murphy, J R.]]
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[[Category: Murphy JR]]
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[[Category: Rangachari, V.]]
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[[Category: Rangachari V]]
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[[Category: Wylie, G P.]]
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[[Category: Wylie GP]]
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[[Category: C-terminal domain]]
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[[Category: Dtxr]]
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[[Category: Gene regulation]]
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[[Category: Peptide-binding]]
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[[Category: Prokaryotic sh3 domain]]
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[[Category: Repressor]]
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[[Category: Transcription regulation]]
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''Page seeded by [http://oca.weizmann.ac.il/oca OCA ] on Sun Jul 27 12:18:42 2008''
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Current revision

Solution Structure of the C-Terminal Domain of DtxR residues 110-226

PDB ID 1qw1

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