1nbj

From Proteopedia

(Difference between revisions)
Jump to: navigation, search
Current revision (07:31, 23 October 2024) (edit) (undo)
 
(10 intermediate revisions not shown.)
Line 1: Line 1:
-
{{Seed}}
 
-
[[Image:1nbj.png|left|200px]]
 
-
<!--
+
==High-resolution solution structure of cycloviolacin O1==
-
The line below this paragraph, containing "STRUCTURE_1nbj", creates the "Structure Box" on the page.
+
<StructureSection load='1nbj' size='340' side='right'caption='[[1nbj]]' scene=''>
-
You may change the PDB parameter (which sets the PDB file loaded into the applet)
+
== Structural highlights ==
-
or the SCENE parameter (which sets the initial scene displayed when the page is loaded),
+
<table><tr><td colspan='2'>[[1nbj]] is a 1 chain structure with sequence from [https://en.wikipedia.org/wiki/Viola_odorata Viola odorata]. Full experimental information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=1NBJ OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=1NBJ FirstGlance]. <br>
-
or leave the SCENE parameter empty for the default display.
+
</td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models|Method:]]</b></td><td class="sblockDat" id="methodDat">Solution NMR, 20 models</td></tr>
-
-->
+
<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=1nbj FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=1nbj OCA], [https://pdbe.org/1nbj PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=1nbj RCSB], [https://www.ebi.ac.uk/pdbsum/1nbj PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=1nbj ProSAT]</span></td></tr>
-
{{STRUCTURE_1nbj| PDB=1nbj | SCENE= }}
+
</table>
 +
== Function ==
 +
[https://www.uniprot.org/uniprot/CYO1_VIOOD CYO1_VIOOD] Probably participates in a plant defense mechanism.
 +
<div style="background-color:#fffaf0;">
 +
== Publication Abstract from PubMed ==
 +
In recent years an increasing number of miniproteins containing an amide-cyclized backbone have been discovered. The cyclotide family is the largest group of such proteins and is characterized by a circular protein backbone and six conserved cysteine residues linked by disulfide bonds in a tight core of the molecule. These form a cystine knot in which an embedded ring formed by two of the disulfide bonds and the connecting backbone segment is threaded by a third disulfide bond. In the current study we have undertaken high resolution structural analysis of two prototypic cyclotides, kalata B1 and cycloviolacin O1, to define the role of the conserved residues in the sequence. We provide the first comprehensive analysis of the topological features in this unique family of proteins, namely rings (a circular backbone), twists (a cis-peptide bond in the Mobius cyclotides) and knots (a knotted arrangement of the disulfide bonds).
-
===High-resolution solution structure of cycloviolacin O1===
+
Twists, knots, and rings in proteins. Structural definition of the cyclotide framework.,Rosengren KJ, Daly NL, Plan MR, Waine C, Craik DJ J Biol Chem. 2003 Mar 7;278(10):8606-16. Epub 2002 Dec 12. PMID:12482868<ref>PMID:12482868</ref>
-
 
+
From MEDLINE&reg;/PubMed&reg;, a database of the U.S. National Library of Medicine.<br>
-
<!--
+
</div>
-
The line below this paragraph, {{ABSTRACT_PUBMED_12482868}}, adds the Publication Abstract to the page
+
<div class="pdbe-citations 1nbj" style="background-color:#fffaf0;"></div>
-
(as it appears on PubMed at http://www.pubmed.gov), where 12482868 is the PubMed ID number.
+
== References ==
-
-->
+
<references/>
-
{{ABSTRACT_PUBMED_12482868}}
+
__TOC__
-
 
+
</StructureSection>
-
==About this Structure==
+
[[Category: Large Structures]]
-
1NBJ is a [[Single protein]] structure of sequence from [http://en.wikipedia.org/wiki/Viola_odorata Viola odorata]. Full experimental information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=1NBJ OCA].
+
-
 
+
-
==Reference==
+
-
Twists, knots, and rings in proteins. Structural definition of the cyclotide framework., Rosengren KJ, Daly NL, Plan MR, Waine C, Craik DJ, J Biol Chem. 2003 Mar 7;278(10):8606-16. Epub 2002 Dec 12. PMID:[http://www.ncbi.nlm.nih.gov/pubmed/12482868 12482868]
+
-
[[Category: Single protein]]
+
[[Category: Viola odorata]]
[[Category: Viola odorata]]
-
[[Category: Craik, D J.]]
+
[[Category: Craik DJ]]
-
[[Category: Daly, N L.]]
+
[[Category: Daly NL]]
-
[[Category: Plan, M R.]]
+
[[Category: Plan MR]]
-
[[Category: Rosengren, K J.]]
+
[[Category: Rosengren KJ]]
-
[[Category: Waine, C.]]
+
[[Category: Waine C]]
-
[[Category: Cck]]
+
-
[[Category: Cyclic backbone]]
+
-
[[Category: Cyclotide]]
+
-
[[Category: Cystine knot]]
+
-
 
+
-
''Page seeded by [http://oca.weizmann.ac.il/oca OCA ] on Sun Jul 27 12:31:19 2008''
+

Current revision

High-resolution solution structure of cycloviolacin O1

PDB ID 1nbj

Drag the structure with the mouse to rotate

Proteopedia Page Contributors and Editors (what is this?)

OCA

Retrieved from "http://52.214.119.220/wiki/index.php/1nbj"
Personal tools