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1noy

From Proteopedia

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{{Seed}}
 
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[[Image:1noy.png|left|200px]]
 
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<!--
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==DNA POLYMERASE (E.C.2.7.7.7)/DNA COMPLEX==
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The line below this paragraph, containing "STRUCTURE_1noy", creates the "Structure Box" on the page.
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<StructureSection load='1noy' size='340' side='right'caption='[[1noy]], [[Resolution|resolution]] 2.20&Aring;' scene=''>
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You may change the PDB parameter (which sets the PDB file loaded into the applet)
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== Structural highlights ==
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or the SCENE parameter (which sets the initial scene displayed when the page is loaded),
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<table><tr><td colspan='2'>[[1noy]] is a 3 chain structure with sequence from [https://en.wikipedia.org/wiki/Escherichia_virus_T4 Escherichia virus T4]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=1NOY OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=1NOY FirstGlance]. <br>
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or leave the SCENE parameter empty for the default display.
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</td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models|Method:]]</b></td><td class="sblockDat" id="methodDat">X-ray diffraction, [[Resolution|Resolution]] 2.2&#8491;</td></tr>
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<tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=MN:MANGANESE+(II)+ION'>MN</scene>, <scene name='pdbligand=ZN:ZINC+ION'>ZN</scene></td></tr>
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{{STRUCTURE_1noy| PDB=1noy | SCENE= }}
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<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=1noy FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=1noy OCA], [https://pdbe.org/1noy PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=1noy RCSB], [https://www.ebi.ac.uk/pdbsum/1noy PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=1noy ProSAT]</span></td></tr>
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</table>
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== Function ==
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[https://www.uniprot.org/uniprot/DPOL_BPT4 DPOL_BPT4] This polymerase possesses two enzymatic activities: DNA synthesis (polymerase) and an exonucleolytic activity that degrades single-stranded DNA in the 3'- to 5'-direction.
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== Evolutionary Conservation ==
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[[Image:Consurf_key_small.gif|200px|right]]
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Check<jmol>
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<jmolCheckbox>
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<scriptWhenChecked>; select protein; define ~consurf_to_do selected; consurf_initial_scene = true; script "/wiki/ConSurf/no/1noy_consurf.spt"</scriptWhenChecked>
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<scriptWhenUnchecked>script /wiki/extensions/Proteopedia/spt/initialview01.spt</scriptWhenUnchecked>
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<text>to colour the structure by Evolutionary Conservation</text>
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</jmolCheckbox>
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</jmol>, as determined by [http://consurfdb.tau.ac.il/ ConSurfDB]. You may read the [[Conservation%2C_Evolutionary|explanation]] of the method and the full data available from [http://bental.tau.ac.il/new_ConSurfDB/main_output.php?pdb_ID=1noy ConSurf].
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<div style="clear:both"></div>
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===DNA POLYMERASE (E.C.2.7.7.7)/DNA COMPLEX===
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==See Also==
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*[[DNA polymerase 3D structures|DNA polymerase 3D structures]]
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__TOC__
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<!--
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</StructureSection>
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The line below this paragraph, {{ABSTRACT_PUBMED_8679562}}, adds the Publication Abstract to the page
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[[Category: Escherichia virus T4]]
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(as it appears on PubMed at http://www.pubmed.gov), where 8679562 is the PubMed ID number.
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[[Category: Large Structures]]
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[[Category: Konigsberg WH]]
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{{ABSTRACT_PUBMED_8679562}}
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[[Category: Lin TC]]
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[[Category: Steitz TA]]
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==About this Structure==
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[[Category: Wang J]]
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1NOY is a [[Single protein]] structure of sequence from [http://en.wikipedia.org/wiki/Enterobacteria_phage_t4 Enterobacteria phage t4]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=1NOY OCA].
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[[Category: Yu P]]
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==Reference==
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Crystal structures of an NH2-terminal fragment of T4 DNA polymerase and its complexes with single-stranded DNA and with divalent metal ions., Wang J, Yu P, Lin TC, Konigsberg WH, Steitz TA, Biochemistry. 1996 Jun 25;35(25):8110-9. PMID:[http://www.ncbi.nlm.nih.gov/pubmed/8679562 8679562]
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[[Category: Enterobacteria phage t4]]
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[[Category: Single protein]]
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[[Category: Konigsberg, W H.]]
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[[Category: Lin, T C.]]
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[[Category: Steitz, T A.]]
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[[Category: Wang, J.]]
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[[Category: Yu, P.]]
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[[Category: Dna-binding]]
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[[Category: Exonuclease]]
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''Page seeded by [http://oca.weizmann.ac.il/oca OCA ] on Sun Jul 27 12:58:38 2008''
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Current revision

DNA POLYMERASE (E.C.2.7.7.7)/DNA COMPLEX

PDB ID 1noy

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