1x7h

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{{Seed}}
 
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[[Image:1x7h.png|left|200px]]
 
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==Actinorhodin Polyketide Ketoreductase, with NADPH bound==
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The line below this paragraph, containing "STRUCTURE_1x7h", creates the "Structure Box" on the page.
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<StructureSection load='1x7h' size='340' side='right'caption='[[1x7h]], [[Resolution|resolution]] 2.30&Aring;' scene=''>
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You may change the PDB parameter (which sets the PDB file loaded into the applet)
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== Structural highlights ==
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or the SCENE parameter (which sets the initial scene displayed when the page is loaded),
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<table><tr><td colspan='2'>[[1x7h]] is a 2 chain structure with sequence from [https://en.wikipedia.org/wiki/Streptomyces_coelicolor Streptomyces coelicolor]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=1X7H OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=1X7H FirstGlance]. <br>
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or leave the SCENE parameter empty for the default display.
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</td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models|Method:]]</b></td><td class="sblockDat" id="methodDat">X-ray diffraction, [[Resolution|Resolution]] 2.3&#8491;</td></tr>
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<tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=NDP:NADPH+DIHYDRO-NICOTINAMIDE-ADENINE-DINUCLEOTIDE+PHOSPHATE'>NDP</scene></td></tr>
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{{STRUCTURE_1x7h| PDB=1x7h | SCENE= }}
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<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=1x7h FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=1x7h OCA], [https://pdbe.org/1x7h PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=1x7h RCSB], [https://www.ebi.ac.uk/pdbsum/1x7h PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=1x7h ProSAT]</span></td></tr>
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</table>
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===Actinorhodin Polyketide Ketoreductase, with NADPH bound===
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== Function ==
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[https://www.uniprot.org/uniprot/ACT3_STRCO ACT3_STRCO]
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== Evolutionary Conservation ==
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[[Image:Consurf_key_small.gif|200px|right]]
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The line below this paragraph, {{ABSTRACT_PUBMED_15544323}}, adds the Publication Abstract to the page
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Check<jmol>
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(as it appears on PubMed at http://www.pubmed.gov), where 15544323 is the PubMed ID number.
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<jmolCheckbox>
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<scriptWhenChecked>; select protein; define ~consurf_to_do selected; consurf_initial_scene = true; script "/wiki/ConSurf/x7/1x7h_consurf.spt"</scriptWhenChecked>
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{{ABSTRACT_PUBMED_15544323}}
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<scriptWhenUnchecked>script /wiki/extensions/Proteopedia/spt/initialview01.spt</scriptWhenUnchecked>
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<text>to colour the structure by Evolutionary Conservation</text>
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==About this Structure==
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</jmolCheckbox>
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1X7H is a [[Single protein]] structure of sequence from [http://en.wikipedia.org/wiki/Streptomyces_coelicolor Streptomyces coelicolor]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=1X7H OCA].
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</jmol>, as determined by [http://consurfdb.tau.ac.il/ ConSurfDB]. You may read the [[Conservation%2C_Evolutionary|explanation]] of the method and the full data available from [http://bental.tau.ac.il/new_ConSurfDB/main_output.php?pdb_ID=1x7h ConSurf].
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<div style="clear:both"></div>
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==Reference==
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__TOC__
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Structural analysis of actinorhodin polyketide ketoreductase: cofactor binding and substrate specificity., Korman TP, Hill JA, Vu TN, Tsai SC, Biochemistry. 2004 Nov 23;43(46):14529-38. PMID:[http://www.ncbi.nlm.nih.gov/pubmed/15544323 15544323]
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</StructureSection>
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[[Category: Single protein]]
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[[Category: Large Structures]]
[[Category: Streptomyces coelicolor]]
[[Category: Streptomyces coelicolor]]
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[[Category: Hill, J A.]]
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[[Category: Hill JA]]
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[[Category: Korman, T P.]]
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[[Category: Korman TP]]
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[[Category: Vu, T N.]]
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[[Category: Vu TN]]
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[[Category: Actinorhodin]]
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[[Category: Combinatorial biosynthesis]]
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[[Category: Ketoreductase]]
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[[Category: Polyketide]]
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[[Category: Short chain dehydrogenase/reductase]]
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''Page seeded by [http://oca.weizmann.ac.il/oca OCA ] on Sun Jul 27 13:09:23 2008''
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Current revision

Actinorhodin Polyketide Ketoreductase, with NADPH bound

PDB ID 1x7h

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