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2p0m

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{{Seed}}
 
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[[Image:2p0m.png|left|200px]]
 
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<!--
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==Revised structure of rabbit reticulocyte 15S-lipoxygenase==
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The line below this paragraph, containing "STRUCTURE_2p0m", creates the "Structure Box" on the page.
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<StructureSection load='2p0m' size='340' side='right'caption='[[2p0m]], [[Resolution|resolution]] 2.40&Aring;' scene=''>
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You may change the PDB parameter (which sets the PDB file loaded into the applet)
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== Structural highlights ==
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or the SCENE parameter (which sets the initial scene displayed when the page is loaded),
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<table><tr><td colspan='2'>[[2p0m]] is a 2 chain structure with sequence from [https://en.wikipedia.org/wiki/Oryctolagus_cuniculus Oryctolagus cuniculus]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=2P0M OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=2P0M FirstGlance]. <br>
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or leave the SCENE parameter empty for the default display.
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</td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models|Method:]]</b></td><td class="sblockDat" id="methodDat">X-ray diffraction, [[Resolution|Resolution]] 2.4&#8491;</td></tr>
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<tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=FE2:FE+(II)+ION'>FE2</scene>, <scene name='pdbligand=RS7:(2E)-3-(2-OCT-1-YN-1-YLPHENYL)ACRYLIC+ACID'>RS7</scene></td></tr>
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{{STRUCTURE_2p0m| PDB=2p0m | SCENE= }}
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<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=2p0m FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=2p0m OCA], [https://pdbe.org/2p0m PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=2p0m RCSB], [https://www.ebi.ac.uk/pdbsum/2p0m PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=2p0m ProSAT]</span></td></tr>
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</table>
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===Revised structure of rabbit reticulocyte 15S-lipoxygenase===
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== Function ==
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[https://www.uniprot.org/uniprot/LOX15_RABIT LOX15_RABIT]
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== Evolutionary Conservation ==
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<!--
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[[Image:Consurf_key_small.gif|200px|right]]
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The line below this paragraph, {{ABSTRACT_PUBMED_17847087}}, adds the Publication Abstract to the page
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Check<jmol>
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(as it appears on PubMed at http://www.pubmed.gov), where 17847087 is the PubMed ID number.
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<jmolCheckbox>
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<scriptWhenChecked>; select protein; define ~consurf_to_do selected; consurf_initial_scene = true; script "/wiki/ConSurf/p0/2p0m_consurf.spt"</scriptWhenChecked>
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{{ABSTRACT_PUBMED_17847087}}
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<scriptWhenUnchecked>script /wiki/extensions/Proteopedia/spt/initialview01.spt</scriptWhenUnchecked>
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<text>to colour the structure by Evolutionary Conservation</text>
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==About this Structure==
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</jmolCheckbox>
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2P0M is a [[Single protein]] structure of sequence from [http://en.wikipedia.org/wiki/Oryctolagus_cuniculus Oryctolagus cuniculus]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=2P0M OCA].
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</jmol>, as determined by [http://consurfdb.tau.ac.il/ ConSurfDB]. You may read the [[Conservation%2C_Evolutionary|explanation]] of the method and the full data available from [http://bental.tau.ac.il/new_ConSurfDB/main_output.php?pdb_ID=2p0m ConSurf].
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<div style="clear:both"></div>
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==Reference==
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__TOC__
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Conformational flexibility in mammalian 15S-lipoxygenase: Reinterpretation of the crystallographic data., Choi J, Chon JK, Kim S, Shin W, Proteins. 2008 Feb 15;70(3):1023-32. PMID:[http://www.ncbi.nlm.nih.gov/pubmed/17847087 17847087]
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</StructureSection>
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[[Category: Large Structures]]
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The structure of mammalian 15-lipoxygenase reveals similarity to the lipases and the determinants of substrate specificity., Gillmor SA, Villasenor A, Fletterick R, Sigal E, Browner MF, Nat Struct Biol. 1997 Dec;4(12):1003-9. PMID:[http://www.ncbi.nlm.nih.gov/pubmed/9406550 9406550]
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[[Category: Arachidonate 15-lipoxygenase]]
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[[Category: Oryctolagus cuniculus]]
[[Category: Oryctolagus cuniculus]]
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[[Category: Single protein]]
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[[Category: Choi J]]
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[[Category: Choi, J.]]
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[[Category: Chon JK]]
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[[Category: Chon, J K.]]
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[[Category: Kim S]]
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[[Category: Kim, S.]]
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[[Category: Shin W]]
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[[Category: Shin, W.]]
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[[Category: 15s-lipoxygenase]]
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[[Category: Arachidonate]]
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[[Category: Conformational change]]
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[[Category: Iron]]
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[[Category: Oxidoreductase]]
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[[Category: Pseudo symmetry]]
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[[Category: Rabbit]]
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[[Category: Twin]]
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''Page seeded by [http://oca.weizmann.ac.il/oca OCA ] on Sun Jul 27 13:20:34 2008''
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Current revision

Revised structure of rabbit reticulocyte 15S-lipoxygenase

PDB ID 2p0m

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